The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Exopolyphosphatase. Domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Ectonucleoside triphosphate diphosphohydrolase 5

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Nucleoside diphosphate phosphatase. [EC: 3.6.1.6]
A nucleoside diphosphate + H(2)O = a nucleoside phosphate + phosphate.
  • The enzyme, which appears to be limited to metazoa, acts on multiple nucleoside diphosphates as well as on D-ribose 5-diphosphate.
  • Specificity depends on species and isoform.
12 A0A024R6D3 A0A024R6D3 D2GZV9 E1BPW0 E1C1L6 O75354 O75356 O75356 Q6P6S9 Q9ER31
(2 more...)
Guanosine-diphosphatase. [EC: 3.6.1.42]
GDP + H(2)O = GMP + phosphate.
  • Also acts on UDP but not on other nucleoside diphosphates and triphosphates.
10 A0A024R6D3 A0A024R6D3 D2GZV9 E1BPW0 E1C1L6 O75356 O75356 Q6P6S9 Q9QYC8 Q9WUZ9
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