The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Ribonuclease H-like superfamily/Ribonuclease H
".
FunFam 11: PAN2-PAN3 deadenylation complex catalytic subunit ...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Poly(A)-specific ribonuclease activity GO:0004535
Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.
|
4 | Q55DD5 (/ISS) Q5F450 (/ISS) Q6IE70 (/ISS) Q8BGF7 (/ISS) |
3'-5'-exoribonuclease activity GO:0000175
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
|
3 | Q5F450 (/ISS) Q6IE70 (/ISS) Q8BGF7 (/ISS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | A1Z7K9 (/IPI) Q504Q3 (/IPI) Q8BGF7 (/IPI) |
3'-5'-exoribonuclease activity GO:0000175
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
|
1 | Q504Q3 (/IDA) |
3'-5'-exoribonuclease activity GO:0000175
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
|
1 | Q8BGF7 (/ISO) |
Poly(A)-specific ribonuclease activity GO:0004535
Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.
|
1 | Q504Q3 (/IDA) |
Poly(A)-specific ribonuclease activity GO:0004535
Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.
|
1 | Q8BGF7 (/ISO) |
Poly(A)-specific ribonuclease activity GO:0004535
Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.
|
1 | Q504Q3 (/TAS) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nuclear-transcribed mRNA poly(A) tail shortening GO:0000289
Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
|
2 | A0A0B4LEY4 (/IGI) A1Z7K9 (/IGI) |
Nuclear-transcribed mRNA poly(A) tail shortening GO:0000289
Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
|
2 | A0A0B4LEY4 (/ISS) A1Z7K9 (/ISS) |
Nuclear-transcribed mRNA poly(A) tail shortening GO:0000289
Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
|
1 | Q8BGF7 (/ISO) |
Nuclear-transcribed mRNA poly(A) tail shortening GO:0000289
Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
|
1 | Q504Q3 (/TAS) |
Nuclear-transcribed mRNA catabolic process, exonucleolytic GO:0000291
The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap or the 3'-poly(A) tail.
|
1 | Q8BGF7 (/ISO) |
Postreplication repair GO:0006301
The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. Includes pathways that remove replication-blocking lesions in conjunction with DNA replication.
|
1 | Q55DD5 (/ISS) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
PAN complex GO:0031251
A complex that possesses poly(A)-specific ribonuclease activity; catalyzes the message-specific shortening of mRNA poly(A) tails. Contains at least two subunits, known as Pan2p and Pan3p in Saccharomyces.
|
6 | A0A0B4LEY4 (/ISS) A1Z7K9 (/ISS) Q55DD5 (/ISS) Q5F450 (/ISS) Q6IE70 (/ISS) Q8BGF7 (/ISS) |
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
1 | Q8BGF7 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q8BGF7 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q504Q3 (/TAS) |
PAN complex GO:0031251
A complex that possesses poly(A)-specific ribonuclease activity; catalyzes the message-specific shortening of mRNA poly(A) tails. Contains at least two subunits, known as Pan2p and Pan3p in Saccharomyces.
|
1 | Q504Q3 (/IDA) |
PAN complex GO:0031251
A complex that possesses poly(A)-specific ribonuclease activity; catalyzes the message-specific shortening of mRNA poly(A) tails. Contains at least two subunits, known as Pan2p and Pan3p in Saccharomyces.
|
1 | Q8BGF7 (/ISO) |