The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Sulfite Reductase Hemoprotein, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate syntha...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin). [EC: 1.17.7.3]
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H(2)O + oxidized flavodoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + reduced flavodoxin.
  • Forms part of an alternative non-mevalonate pathway for isoprenoid biosynthesis that is found in most bacteria.
  • Plants and cyanobacteria have a similar enzyme that utilizes ferredoxin rather than flavodoxin (cf. EC 1.17.7.1).
92 A0A0F6HE82 A0A0F6HE82 A0A0F6HE82 A0A0F6HE82 A0A0F6HE82 A0A0F6HY49 A0A0F6HY49 A0A0F6HY49 A0A0F6HY49 A0A0F6HY49
(82 more...)
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin). [EC: 1.17.7.1]
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H(2)O + 2 oxidized ferredoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + 2 reduced ferredoxin.
  • Forms part of an alternative non-mevalonate pathway for isoprenoid biosynthesis.
  • Bacteria have a similar enzyme that uses flavodoxin rather than ferredoxin (cf. EC 1.17.7.3).
  • The enzyme from the plant Arabidopsis thaliana is active with photoreduced 5-deazaflavin but not with flavodoxin.
  • Formerly EC 1.17.4.3.
32 A0A0D3F7B7 A0A0D3F7B7 A0A0D3F7B7 A0A0D3F7B7 A0A178UN53 A0A178UN53 A0A3E0LES3 A0A3E0LES3 A0A3E0LES3 B0JJJ8
(22 more...)
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