The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Zinc/RING finger domain, C3HC4 (zinc finger)
".
FunFam 16: Inhibitor of growth protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Methylated histone binding GO:0035064
Interacting selectively and non-covalently with a histone in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes.
|
24 |
P50947 (/IDA)
P50947 (/IDA)
P50947 (/IDA)
P50947 (/IDA)
P50947 (/IDA)
P50947 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
(14 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
20 |
Q8C0D7 (/IPI)
Q8C0D7 (/IPI)
Q8WYH8 (/IPI)
Q8WYH8 (/IPI)
Q8WYH8 (/IPI)
Q8WYH8 (/IPI)
Q8WYH8 (/IPI)
Q8WYH8 (/IPI)
Q8WYH8 (/IPI)
Q9UNL4 (/IPI)
(10 more) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
11 |
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
(1 more) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
3 | Q3T095 (/ISS) Q8C0D7 (/ISS) Q8C0D7 (/ISS) |
|
Methylated histone binding GO:0035064
Interacting selectively and non-covalently with a histone in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes.
|
3 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) Q9D8Y8 (/ISO) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
2 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
1 | Q9D8Y8 (/IDA) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
1 | Q9D8Y8 (/IGI) |
There are 57 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
|
20 |
Q8IP71 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
(10 more) |
|
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
|
18 |
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
(8 more) |
|
Protein acetylation GO:0006473
The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic
|
18 |
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
(8 more) |
|
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
18 |
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
(8 more) |
|
Negative regulation of growth GO:0045926
Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
|
18 |
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
(8 more) |
|
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
13 |
Q8C0D7 (/IDA)
Q8C0D7 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
(3 more) |
|
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
|
11 |
Q5ZKY4 (/ISS)
Q5ZKY4 (/ISS)
Q5ZKY4 (/ISS)
Q5ZKY4 (/ISS)
Q5ZKY4 (/ISS)
Q5ZKY4 (/ISS)
Q5ZKY4 (/ISS)
Q5ZKY4 (/ISS)
Q8C0D7 (/ISS)
Q8C0D7 (/ISS)
(1 more) |
|
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
|
11 |
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
(1 more) |
|
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage.
|
11 |
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
(1 more) |
|
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
|
11 |
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
(1 more) |
|
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
11 |
Q3T095 (/ISS)
Q5ZKY4 (/ISS)
Q5ZKY4 (/ISS)
Q5ZKY4 (/ISS)
Q5ZKY4 (/ISS)
Q5ZKY4 (/ISS)
Q5ZKY4 (/ISS)
Q5ZKY4 (/ISS)
Q5ZKY4 (/ISS)
Q8C0D7 (/ISS)
(1 more) |
|
Histone H4-K5 acetylation GO:0043981
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone.
|
11 |
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
(1 more) |
|
Histone H4-K8 acetylation GO:0043982
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone.
|
11 |
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
(1 more) |
|
Histone H4-K12 acetylation GO:0043983
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone.
|
11 |
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
(1 more) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
11 |
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
(1 more) |
|
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
8 | Q8WYH8 (/IGI) Q8WYH8 (/IGI) Q8WYH8 (/IGI) Q8WYH8 (/IGI) Q8WYH8 (/IGI) Q8WYH8 (/IGI) Q8WYH8 (/IGI) Q9D8Y8 (/IGI) |
|
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
7 | Q8WYH8 (/IGI) Q8WYH8 (/IGI) Q8WYH8 (/IGI) Q8WYH8 (/IGI) Q8WYH8 (/IGI) Q8WYH8 (/IGI) Q8WYH8 (/IGI) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
7 | Q8WYH8 (/IDA) Q8WYH8 (/IDA) Q8WYH8 (/IDA) Q8WYH8 (/IDA) Q8WYH8 (/IDA) Q8WYH8 (/IDA) Q8WYH8 (/IDA) |
|
Regulation of signal transduction by p53 class mediator GO:1901796
Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.
|
7 | Q8WYH8 (/TAS) Q8WYH8 (/TAS) Q8WYH8 (/TAS) Q8WYH8 (/TAS) Q8WYH8 (/TAS) Q8WYH8 (/TAS) Q8WYH8 (/TAS) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
6 | P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) |
|
Chromatin organization GO:0006325
Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.
|
6 | P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) |
|
Negative regulation of autophagy GO:0010507
Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
6 | P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) |
|
Negative regulation of transcription by RNA polymerase I GO:0016479
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase I.
|
6 | P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) |
|
Negative regulation of chromatin silencing at telomere GO:0031939
Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing at telomeres.
|
6 | P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
6 | P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) |
|
Negative regulation of chromatin silencing at silent mating-type cassette GO:0061186
Any process that decreases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin.
|
6 | P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) |
|
Negative regulation of chromatin silencing at rDNA GO:0061188
Any process that decreases the rate, frequency, or extent of the repression of transcription of ribosomal DNA by altering the structure of chromatin.
|
6 | P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) |
|
Positive regulation of transcription from RNA polymerase II promoter in response to heat stress GO:0061408
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
6 | P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) |
|
Positive regulation of invasive growth in response to glucose limitation GO:2000219
Any process that activates or increases the frequency, rate or extent of invasive growth in response to glucose limitation.
|
6 | P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) |
|
Regulation of protein localization by the Cvt pathway GO:2001159
Any process that modulates the frequency, rate or extent of protein localization by the Cvt pathway.
|
6 | P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) P50947 (/IMP) |
|
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
|
4 | Q3T095 (/ISS) Q8C0D7 (/ISS) Q8C0D7 (/ISS) Q9D8Y8 (/ISS) |
|
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
|
3 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) Q9D8Y8 (/ISO) |
|
Protein acetylation GO:0006473
The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic
|
3 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) Q9D8Y8 (/ISO) |
|
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage.
|
3 | Q3T095 (/ISS) Q8C0D7 (/ISS) Q8C0D7 (/ISS) |
|
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
3 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) Q9D8Y8 (/ISO) |
|
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
3 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) Q9D8Y8 (/ISO) |
|
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
|
3 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) Q9D8Y8 (/ISO) |
|
Histone H4-K5 acetylation GO:0043981
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone.
|
3 | Q3T095 (/ISS) Q8C0D7 (/ISS) Q8C0D7 (/ISS) |
|
Histone H4-K8 acetylation GO:0043982
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone.
|
3 | Q3T095 (/ISS) Q8C0D7 (/ISS) Q8C0D7 (/ISS) |
|
Histone H4-K12 acetylation GO:0043983
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone.
|
3 | Q3T095 (/ISS) Q8C0D7 (/ISS) Q8C0D7 (/ISS) |
|
Negative regulation of growth GO:0045926
Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
|
3 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) Q9D8Y8 (/ISO) |
|
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
|
2 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) |
|
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage.
|
2 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) |
|
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
|
2 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) |
|
Histone H4-K5 acetylation GO:0043981
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone.
|
2 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) |
|
Histone H4-K8 acetylation GO:0043982
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone.
|
2 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) |
|
Histone H4-K12 acetylation GO:0043983
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone.
|
2 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) |
|
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
|
2 | Q8IP71 (/IDA) Q9VJY8 (/IDA) |
|
Hematopoietic progenitor cell differentiation GO:0002244
The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
|
1 | Q4VBS0 (/IMP) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q54PN9 (/IMP) |
|
Histone modification GO:0016570
The covalent alteration of one or more amino acid residues within a histone protein.
|
1 | Q54PN9 (/IMP) |
|
Aggregation involved in sorocarp development GO:0031152
The process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.
|
1 | Q54PN9 (/IMP) |
|
Phenotypic switching GO:0036166
A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues.
|
1 | A0A1D8PIP3 (/IMP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q9D8Y8 (/ISO) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q9D8Y8 (/ISS) |
|
Positive regulation of apoptotic signaling pathway GO:2001235
Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.
|
1 | Q9D8Y8 (/IGI) |
There are 20 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
21 |
Q54PN9 (/IDA)
Q8C0D7 (/IDA)
Q8C0D7 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
Q8WYH8 (/IDA)
(11 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
18 |
Q8WYH8 (/TAS)
Q8WYH8 (/TAS)
Q8WYH8 (/TAS)
Q8WYH8 (/TAS)
Q8WYH8 (/TAS)
Q8WYH8 (/TAS)
Q8WYH8 (/TAS)
Q9UNL4 (/TAS)
Q9UNL4 (/TAS)
Q9UNL4 (/TAS)
(8 more) |
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Histone acetyltransferase complex GO:0000123
A protein complex that possesses histone acetyltransferase activity.
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11 |
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
(1 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
11 |
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
(1 more) |
|
Intermediate filament cytoskeleton GO:0045111
Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.
|
11 |
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
Q9UNL4 (/IDA)
(1 more) |
|
MOZ/MORF histone acetyltransferase complex GO:0070776
A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.
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9 | Q8IP71 (/IDA) Q8WYH8 (/IDA) Q8WYH8 (/IDA) Q8WYH8 (/IDA) Q8WYH8 (/IDA) Q8WYH8 (/IDA) Q8WYH8 (/IDA) Q8WYH8 (/IDA) Q9VJY8 (/IDA) |
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Histone deacetylase complex GO:0000118
A protein complex that possesses histone deacetylase activity.
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6 | P50947 (/IDA) P50947 (/IDA) P50947 (/IDA) P50947 (/IDA) P50947 (/IDA) P50947 (/IDA) |
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Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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6 | P50947 (/HDA) P50947 (/HDA) P50947 (/HDA) P50947 (/HDA) P50947 (/HDA) P50947 (/HDA) |
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Rpd3L complex GO:0033698
A histone deacetylase complex which deacetylates histones across gene coding regions. Composed of a catalytic histone deacetylase subunit, an Sds-3 family protein, a SIN3 family co-repressor, a WD repeat protein, and a zf- PHD finger (Clr6, Sds3, Pst1, Prw1, Png2 in Schizosaccharomyces pombe; Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p and Ash1p in Saccharomyces cerevisiae).
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6 | P50947 (/HDA) P50947 (/HDA) P50947 (/HDA) P50947 (/HDA) P50947 (/HDA) P50947 (/HDA) |
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Rpd3L complex GO:0033698
A histone deacetylase complex which deacetylates histones across gene coding regions. Composed of a catalytic histone deacetylase subunit, an Sds-3 family protein, a SIN3 family co-repressor, a WD repeat protein, and a zf- PHD finger (Clr6, Sds3, Pst1, Prw1, Png2 in Schizosaccharomyces pombe; Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p and Ash1p in Saccharomyces cerevisiae).
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6 | P50947 (/IDA) P50947 (/IDA) P50947 (/IDA) P50947 (/IDA) P50947 (/IDA) P50947 (/IDA) |
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Rpd3L-Expanded complex GO:0070210
A protein complex that contains a histone deacetylase and is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains the Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p, Ash1p, Dot6p, Snt1, Sif2p, Set3p, Hos2p, Tos4p and Tod6p proteins.
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6 | P50947 (/HDA) P50947 (/HDA) P50947 (/HDA) P50947 (/HDA) P50947 (/HDA) P50947 (/HDA) |
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Histone acetyltransferase complex GO:0000123
A protein complex that possesses histone acetyltransferase activity.
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3 | Q3T095 (/ISS) Q8C0D7 (/ISS) Q8C0D7 (/ISS) |
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Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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3 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) Q9D8Y8 (/ISO) |
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Histone acetyltransferase complex GO:0000123
A protein complex that possesses histone acetyltransferase activity.
|
2 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) |
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Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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2 | Q3T095 (/ISS) Q9D8Y8 (/ISS) |
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Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
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2 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) |
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Intermediate filament cytoskeleton GO:0045111
Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.
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2 | Q8C0D7 (/ISO) Q8C0D7 (/ISO) |
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Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
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1 | Q54PN9 (/IDA) |
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MOZ/MORF histone acetyltransferase complex GO:0070776
A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.
|
1 | Q9D8Y8 (/ISO) |
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MOZ/MORF histone acetyltransferase complex GO:0070776
A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.
|
1 | Q9D8Y8 (/ISS) |
