The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Zinc/RING finger domain, C3HC4 (zinc finger)
".
FunFam 152: E3 ubiquitin-protein ligase Praja-1 isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | O43164 (/IPI) O55176 (/IPI) O55176 (/IPI) Q80U04 (/IPI) Q8NG27 (/IPI) |
|
Protein kinase A catalytic subunit binding GO:0034236
Interacting selectively and non-covalently with one or both of the catalytic subunits of protein kinase A.
|
3 | Q5R4R1 (/ISS) Q63364 (/ISS) Q80U04 (/ISS) |
|
Protein kinase A regulatory subunit binding GO:0034237
Interacting selectively and non-covalently with one or both of the regulatory subunits of protein kinase A.
|
3 | Q5R4R1 (/ISS) Q63364 (/ISS) Q80U04 (/ISS) |
|
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
2 | O55176 (/IDA) O55176 (/IDA) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
1 | O43164 (/IDA) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
1 | Q80U04 (/ISO) |
|
Protein kinase A catalytic subunit binding GO:0034236
Interacting selectively and non-covalently with one or both of the catalytic subunits of protein kinase A.
|
1 | O43164 (/IMP) |
|
Protein kinase A catalytic subunit binding GO:0034236
Interacting selectively and non-covalently with one or both of the catalytic subunits of protein kinase A.
|
1 | Q80U04 (/ISO) |
|
Protein kinase A regulatory subunit binding GO:0034237
Interacting selectively and non-covalently with one or both of the regulatory subunits of protein kinase A.
|
1 | O43164 (/IMP) |
|
Protein kinase A regulatory subunit binding GO:0034237
Interacting selectively and non-covalently with one or both of the regulatory subunits of protein kinase A.
|
1 | Q80U04 (/ISO) |
There are 28 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
3 | Q5R4R1 (/ISS) Q63364 (/ISS) Q80U04 (/ISS) |
|
Long-term memory GO:0007616
The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.
|
3 | O43164 (/ISS) Q5R4R1 (/ISS) Q80U04 (/ISS) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
3 | Q5R4R1 (/ISS) Q63364 (/ISS) Q80U04 (/ISS) |
|
Positive regulation of toll-like receptor 2 signaling pathway GO:0034137
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway.
|
3 | Q5R4R1 (/ISS) Q63364 (/ISS) Q80U04 (/ISS) |
|
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
|
3 | Q5R4R1 (/ISS) Q63364 (/ISS) Q80U04 (/ISS) |
|
Positive regulation of JNK cascade GO:0046330
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade.
|
3 | Q5R4R1 (/ISS) Q63364 (/ISS) Q80U04 (/ISS) |
|
Positive regulation of p38MAPK cascade GO:1900745
Any process that activates or increases the frequency, rate or extent of p38MAPK cascade.
|
3 | Q5R4R1 (/ISS) Q63364 (/ISS) Q80U04 (/ISS) |
|
Regulation of protein kinase A signaling GO:0010738
Any process that modulates the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.
|
2 | O43164 (/IMP) Q63364 (/IMP) |
|
Regulation of protein kinase A signaling GO:0010738
Any process that modulates the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.
|
2 | Q5R4R1 (/ISS) Q80U04 (/ISS) |
|
Protein catabolic process GO:0030163
The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
2 | O55176 (/IDA) O55176 (/IDA) |
|
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
1 | O43164 (/IMP) |
|
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
1 | Q80U04 (/ISO) |
|
Long-term memory GO:0007616
The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.
|
1 | Q63364 (/IMP) |
|
Long-term memory GO:0007616
The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.
|
1 | Q80U04 (/ISO) |
|
Regulation of protein kinase A signaling GO:0010738
Any process that modulates the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.
|
1 | Q80U04 (/ISO) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
1 | O43164 (/IDA) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
1 | O43164 (/IMP) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
1 | Q80U04 (/ISO) |
|
Positive regulation of toll-like receptor 2 signaling pathway GO:0034137
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway.
|
1 | O43164 (/IMP) |
|
Positive regulation of toll-like receptor 2 signaling pathway GO:0034137
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway.
|
1 | Q80U04 (/ISO) |
|
Regulation of macrophage activation GO:0043030
Any process that modulates the frequency or rate of macrophage activation.
|
1 | O43164 (/IMP) |
|
Regulation of macrophage activation GO:0043030
Any process that modulates the frequency or rate of macrophage activation.
|
1 | Q80U04 (/ISO) |
|
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
|
1 | O43164 (/IMP) |
|
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
|
1 | Q80U04 (/ISO) |
|
Positive regulation of JNK cascade GO:0046330
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade.
|
1 | O43164 (/IMP) |
|
Positive regulation of JNK cascade GO:0046330
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade.
|
1 | Q80U04 (/ISO) |
|
Positive regulation of p38MAPK cascade GO:1900745
Any process that activates or increases the frequency, rate or extent of p38MAPK cascade.
|
1 | O43164 (/IMP) |
|
Positive regulation of p38MAPK cascade GO:1900745
Any process that activates or increases the frequency, rate or extent of p38MAPK cascade.
|
1 | Q80U04 (/ISO) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | O43164 (/IDA) O55176 (/IDA) O55176 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | Q5R4R1 (/ISS) Q63364 (/ISS) Q80U04 (/ISS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q5R4R1 (/ISS) Q80U04 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q80U04 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | O43164 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q80U04 (/ISO) |
|
Intermediate filament cytoskeleton GO:0045111
Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.
|
1 | O43164 (/IDA) |
|
Intermediate filament cytoskeleton GO:0045111
Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.
|
1 | Q80U04 (/ISO) |