The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Zinc/RING finger domain, C3HC4 (zinc finger)
".
FunFam 102: protrudin isoform X2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
|
5 | Q3TXX3 (/ISS) Q5BIM5 (/ISS) Q5R7K2 (/ISS) Q5ZL36 (/ISS) Q6P7B7 (/ISS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q3TXX3 (/IPI) Q5T4F4 (/IPI) |
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
|
1 | Q5T4F4 (/IDA) |
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
|
1 | Q3TXX3 (/ISO) |
There are 20 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Positive regulation of axon extension GO:0045773
Any process that activates or increases the frequency, rate or extent of axon extension.
|
5 | Q5BIM5 (/ISS) Q5R7K2 (/ISS) Q5T4F4 (/ISS) Q5ZL36 (/ISS) Q6P7B7 (/ISS) |
Neurotrophin TRK receptor signaling pathway GO:0048011
A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
|
5 | Q3TXX3 (/ISS) Q5BIM5 (/ISS) Q5R7K2 (/ISS) Q5T4F4 (/ISS) Q5ZL36 (/ISS) |
Endoplasmic reticulum tubular network formation GO:0071787
The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.
|
5 | Q3TXX3 (/ISS) Q5BIM5 (/ISS) Q5R7K2 (/ISS) Q5ZL36 (/ISS) Q6P7B7 (/ISS) |
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
|
5 | Q3TXX3 (/ISS) Q5BIM5 (/ISS) Q5R7K2 (/ISS) Q5T4F4 (/ISS) Q5ZL36 (/ISS) |
Vesicle-mediated transport GO:0016192
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
|
4 | Q5BIM5 (/ISS) Q5R7K2 (/ISS) Q5ZL36 (/ISS) Q6P7B7 (/ISS) |
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
4 | Q3TXX3 (/ISS) Q5BIM5 (/ISS) Q5R7K2 (/ISS) Q5ZL36 (/ISS) |
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
|
3 | F1QVN6 (/IGI) F1R9A8 (/IGI) Q08BM9 (/IGI) |
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
|
3 | F1QVN6 (/IMP) F1R9A8 (/IMP) Q08BM9 (/IMP) |
Vesicle-mediated transport GO:0016192
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
|
2 | Q3TXX3 (/IDA) Q5T4F4 (/IDA) |
Vesicle-mediated transport GO:0016192
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
|
1 | Q3TXX3 (/ISO) |
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
1 | Q5T4F4 (/IDA) |
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
1 | Q6P7B7 (/IMP) |
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
1 | Q3TXX3 (/ISO) |
Positive regulation of axon extension GO:0045773
Any process that activates or increases the frequency, rate or extent of axon extension.
|
1 | Q3TXX3 (/IMP) |
Neurotrophin TRK receptor signaling pathway GO:0048011
A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q6P7B7 (/IMP) |
Neurotrophin TRK receptor signaling pathway GO:0048011
A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q3TXX3 (/ISO) |
Endoplasmic reticulum tubular network formation GO:0071787
The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.
|
1 | Q5T4F4 (/IMP) |
Endoplasmic reticulum tubular network formation GO:0071787
The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.
|
1 | Q3TXX3 (/ISO) |
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
|
1 | Q6P7B7 (/IDA) |
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
|
1 | Q3TXX3 (/ISO) |
There are 26 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
5 | Q3TXX3 (/ISS) Q5BIM5 (/ISS) Q5R7K2 (/ISS) Q5ZL36 (/ISS) Q6P7B7 (/ISS) |
Integral component of endoplasmic reticulum membrane GO:0030176
The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
5 | Q3TXX3 (/ISS) Q5BIM5 (/ISS) Q5R7K2 (/ISS) Q5ZL36 (/ISS) Q6P7B7 (/ISS) |
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
|
5 | Q5BIM5 (/ISS) Q5R7K2 (/ISS) Q5T4F4 (/ISS) Q5ZL36 (/ISS) Q6P7B7 (/ISS) |
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
|
5 | Q5BIM5 (/ISS) Q5R7K2 (/ISS) Q5T4F4 (/ISS) Q5ZL36 (/ISS) Q6P7B7 (/ISS) |
Recycling endosome membrane GO:0055038
The lipid bilayer surrounding a recycling endosome.
|
5 | Q3TXX3 (/ISS) Q5BIM5 (/ISS) Q5R7K2 (/ISS) Q5T4F4 (/ISS) Q5ZL36 (/ISS) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
4 | Q5BIM5 (/ISS) Q5R7K2 (/ISS) Q5ZL36 (/ISS) Q6P7B7 (/ISS) |
Growth cone membrane GO:0032584
The portion of the plasma membrane surrounding a growth cone.
|
4 | Q5BIM5 (/ISS) Q5R7K2 (/ISS) Q5T4F4 (/ISS) Q5ZL36 (/ISS) |
Endoplasmic reticulum tubular network GO:0071782
A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section.
|
4 | Q5BIM5 (/ISS) Q5R7K2 (/ISS) Q5ZL36 (/ISS) Q6P7B7 (/ISS) |
Growth cone membrane GO:0032584
The portion of the plasma membrane surrounding a growth cone.
|
2 | Q3TXX3 (/IDA) Q6P7B7 (/IDA) |
Endoplasmic reticulum tubular network GO:0071782
A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section.
|
2 | Q3TXX3 (/IDA) Q5T4F4 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q5T4F4 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q3TXX3 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q3TXX3 (/IDA) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | Q5T4F4 (/IDA) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | Q3TXX3 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q5T4F4 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q3TXX3 (/ISO) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q3TXX3 (/IDA) |
Integral component of endoplasmic reticulum membrane GO:0030176
The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q5T4F4 (/IDA) |
Integral component of endoplasmic reticulum membrane GO:0030176
The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q3TXX3 (/ISO) |
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
|
1 | Q3TXX3 (/IDA) |
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
|
1 | Q3TXX3 (/IDA) |
Growth cone membrane GO:0032584
The portion of the plasma membrane surrounding a growth cone.
|
1 | Q3TXX3 (/ISO) |
Recycling endosome membrane GO:0055038
The lipid bilayer surrounding a recycling endosome.
|
1 | Q6P7B7 (/IDA) |
Recycling endosome membrane GO:0055038
The lipid bilayer surrounding a recycling endosome.
|
1 | Q3TXX3 (/ISO) |
Endoplasmic reticulum tubular network GO:0071782
A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section.
|
1 | Q3TXX3 (/ISO) |