The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"CO dehydrogenase flavoprotein, C-terminal domain
".
FunFam 3: Aldehyde oxidase1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 19 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Aldehyde oxidase activity GO:0004031
Catalysis of the reaction: an aldehyde + H2O + O2 = a carboxylic acid + hydrogen peroxide.
|
5 | Q7G191 (/IMP) Q7G191 (/IMP) Q8IND5 (/IMP) Q8SXA6 (/IMP) Q9VF51 (/IMP) |
|
Aldehyde oxidase activity GO:0004031
Catalysis of the reaction: an aldehyde + H2O + O2 = a carboxylic acid + hydrogen peroxide.
|
3 | Q7G192 (/IDA) Q7G193 (/IDA) Q7G9P4 (/IDA) |
|
Indole-3-acetaldehyde oxidase activity GO:0050302
Catalysis of the reaction: (indol-3-yl)acetaldehyde + H(2)O + O(2) = (indol-3-yl)acetate + H(2)O(2) + H(+).
|
3 | O23887 (/IDA) Q7G193 (/IDA) Q7G9P4 (/IDA) |
|
Benzaldehyde dehydrogenase (NAD+) activity GO:0018479
Catalysis of the reaction: benzaldehyde + NAD+ + H2O = benzoate + NADH + H+.
|
2 | Q7G191 (/IDA) Q7G191 (/IDA) |
|
Aryl-aldehyde oxidase activity GO:0018488
Catalysis of the reaction: an aromatic aldehyde + O2 + H2O = an aromatic acid + hydrogen peroxide.
|
2 | Q7G191 (/IDA) Q7G191 (/IDA) |
|
Molybdopterin cofactor binding GO:0043546
Interacting selectively and non-covalently with the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
|
2 | O23888 (/ISS) R4ZGN4 (/ISS) |
|
Aldehyde oxidase activity GO:0004031
Catalysis of the reaction: an aldehyde + H2O + O2 = a carboxylic acid + hydrogen peroxide.
|
1 | Q9VF50 (/ISS) |
|
Pyridoxal oxidase activity GO:0004732
Catalysis of the reaction: pyridoxal + H2O + O2 = 4-pyridoxate + hydrogen peroxide.
|
1 | Q9VF53 (/IDA) |
|
Pyridoxal oxidase activity GO:0004732
Catalysis of the reaction: pyridoxal + H2O + O2 = 4-pyridoxate + hydrogen peroxide.
|
1 | Q9VF53 (/IMP) |
|
Xanthine dehydrogenase activity GO:0004854
Catalysis of the reaction: xanthine + NAD+ + H2O = urate + NADH + H+.
|
1 | R4ZGN4 (/IDA) |
|
Abscisic aldehyde oxidase activity GO:0010293
Catalysis of the reaction: (+)-abscisic aldehyde + H(2)O + O(2) = abscisate + H(2)O(2) + H(+).
|
1 | Q7G9P4 (/IDA) |
|
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
1 | Q7G9P4 (/IPI) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | R4ZGN4 (/IDA) |
|
Molybdopterin cofactor binding GO:0043546
Interacting selectively and non-covalently with the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
|
1 | O23887 (/IDA) |
|
Indole-3-acetaldehyde oxidase activity GO:0050302
Catalysis of the reaction: (indol-3-yl)acetaldehyde + H(2)O + O(2) = (indol-3-yl)acetate + H(2)O(2) + H(+).
|
1 | O23888 (/ISS) |
|
Flavin adenine dinucleotide binding GO:0050660
Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
|
1 | R4ZGN4 (/ISS) |
|
2 iron, 2 sulfur cluster binding GO:0051537
Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
|
1 | R4ZGN4 (/ISS) |
|
FAD binding GO:0071949
Interacting selectively and non-covalently with the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
|
1 | O23887 (/IDA) |
|
FAD binding GO:0071949
Interacting selectively and non-covalently with the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
|
1 | O23888 (/ISS) |
There are 25 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Acetaldehyde metabolic process GO:0006117
The chemical reactions and pathways involving acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.
|
2 | Q8SXA6 (/IMP) Q9VF51 (/IMP) |
|
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
|
2 | Q7G191 (/IEP) Q7G191 (/IEP) |
|
Glucosinolate metabolic process GO:0019760
The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans.
|
2 | Q7G191 (/IMP) Q7G191 (/IMP) |
|
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
|
2 | Q7G191 (/IEP) Q7G191 (/IEP) |
|
Cellular response to aldehyde GO:0110096
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus.
|
2 | Q7G191 (/IEP) Q7G191 (/IEP) |
|
Cellular aldehyde metabolic process GO:0006081
The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.
|
1 | Q8IND5 (/IMP) |
|
Cellular aldehyde metabolic process GO:0006081
The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.
|
1 | Q9VF50 (/ISS) |
|
Purine nucleobase catabolic process GO:0006145
The chemical reactions and pathways resulting in the breakdown of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
|
1 | R4ZGN4 (/IDA) |
|
Guanine catabolic process GO:0006147
The chemical reactions and pathways resulting in the breakdown of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.
|
1 | R4ZGN4 (/IDA) |
|
Hypoxanthine oxidation GO:0006150
The chemical reactions and pathways resulting in the breakdown of hypoxanthine to xanthine and thence to uric acid.
|
1 | R4ZGN4 (/IDA) |
|
Xanthine oxidation GO:0006151
The oxidation of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.
|
1 | R4ZGN4 (/IDA) |
|
Abscisic acid biosynthetic process GO:0009688
The chemical reactions and pathways resulting in the formation of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.
|
1 | Q7G9P4 (/IMP) |
|
Auxin biosynthetic process GO:0009851
The chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.
|
1 | O23887 (/IDA) |
|
Auxin biosynthetic process GO:0009851
The chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.
|
1 | Q7G193 (/IMP) |
|
Auxin biosynthetic process GO:0009851
The chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.
|
1 | O23888 (/ISS) |
|
Pyridoxal metabolic process GO:0042817
The chemical reactions and pathways involving 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
|
1 | Q9VF53 (/IMP) |
|
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
|
1 | O23887 (/IDA) |
|
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
|
1 | Q8IND5 (/IMP) |
|
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
|
1 | O23888 (/ISS) |
|
Cellular response to ammonium ion GO:0071242
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium ion stimulus.
|
1 | R4ZGN4 (/IEP) |
|
Cellular response to nitrate GO:0071249
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus.
|
1 | R4ZGN4 (/IEP) |
|
Cellular response to cadmium ion GO:0071276
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
|
1 | R4ZGN4 (/IDA) |
|
Cellular response to copper ion GO:0071280
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
|
1 | R4ZGN4 (/IDA) |
|
Cellular response to iron ion GO:0071281
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
|
1 | R4ZGN4 (/IDA) |
|
Cellular response to zinc ion GO:0071294
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
|
1 | R4ZGN4 (/IDA) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q7G192 (/IDA) Q7G9P4 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q7G191 (/TAS) Q7G191 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | R4ZGN4 (/IDA) |
