The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Dihydrodipicolinate Reductase; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 6: Bifunctional aspartokinase/homoserine dehydrogenas...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Homoserine dehydrogenase activity GO:0004412
Catalysis of the reaction: L-homoserine + NADP+ = L-aspartate-4-semialdehyde + NADPH + H+.
104 O81852 (/IDA) O81852 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA)
(94 more)
Aspartate kinase activity GO:0004072
Catalysis of the reaction: L-aspartate + ATP = 4-phospho-L-aspartate + ADP + H(+).
96 O81852 (/IDA) O81852 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA)
(86 more)
Aspartate kinase activity GO:0004072
Catalysis of the reaction: L-aspartate + ATP = 4-phospho-L-aspartate + ADP + H(+).
11 Q9KNP7 (/ISS) Q9KNP7 (/ISS) Q9KNP7 (/ISS) Q9KNP7 (/ISS) Q9KNP7 (/ISS) Q9KNP7 (/ISS) Q9KNP7 (/ISS) Q9KPK3 (/ISS) Q9KPK3 (/ISS) Q9KPK3 (/ISS)
(1 more)
Homoserine dehydrogenase activity GO:0004412
Catalysis of the reaction: L-homoserine + NADP+ = L-aspartate-4-semialdehyde + NADPH + H+.
11 Q9KNP7 (/ISS) Q9KNP7 (/ISS) Q9KNP7 (/ISS) Q9KNP7 (/ISS) Q9KNP7 (/ISS) Q9KNP7 (/ISS) Q9KNP7 (/ISS) Q9KPK3 (/ISS) Q9KPK3 (/ISS) Q9KPK3 (/ISS)
(1 more)
Homoserine dehydrogenase activity GO:0004412
Catalysis of the reaction: L-homoserine + NADP+ = L-aspartate-4-semialdehyde + NADPH + H+.
1 O94671 (/ISO)
Homoserine dehydrogenase activity GO:0004412
Catalysis of the reaction: L-homoserine + NADP+ = L-aspartate-4-semialdehyde + NADPH + H+.
1 Q5B998 (/RCA)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lysine biosynthetic process via diaminopimelate GO:0009089
The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.
93 P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA)
(83 more)
Homoserine biosynthetic process GO:0009090
The chemical reactions and pathways resulting in the formation of homoserine, alpha-amino-gamma-hydroxybutyric acid.
93 P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA) P00561 (/IDA)
(83 more)
Methionine biosynthetic process GO:0009086
The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
9 P31116 (/IMP) P31116 (/IMP) P31116 (/IMP) P31116 (/IMP) P31116 (/IMP) P31116 (/IMP) P31116 (/IMP) P31116 (/IMP) Q5AIA2 (/IMP)
Threonine biosynthetic process GO:0009088
The chemical reactions and pathways resulting in the formation of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.
9 P31116 (/IMP) P31116 (/IMP) P31116 (/IMP) P31116 (/IMP) P31116 (/IMP) P31116 (/IMP) P31116 (/IMP) P31116 (/IMP) Q5AIA2 (/IMP)
Homoserine biosynthetic process GO:0009090
The chemical reactions and pathways resulting in the formation of homoserine, alpha-amino-gamma-hydroxybutyric acid.
9 P31116 (/IMP) P31116 (/IMP) P31116 (/IMP) P31116 (/IMP) P31116 (/IMP) P31116 (/IMP) P31116 (/IMP) P31116 (/IMP) Q5AIA2 (/IMP)
Methionine biosynthetic process GO:0009086
The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
7 Q9KNP7 (/ISS) Q9KNP7 (/ISS) Q9KNP7 (/ISS) Q9KNP7 (/ISS) Q9KNP7 (/ISS) Q9KNP7 (/ISS) Q9KNP7 (/ISS)
Threonine biosynthetic process GO:0009088
The chemical reactions and pathways resulting in the formation of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.
4 Q9KPK3 (/ISS) Q9KPK3 (/ISS) Q9KPK3 (/ISS) Q9KPK3 (/ISS)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
1 Q5B998 (/RCA)
Methionine biosynthetic process GO:0009086
The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
1 O94671 (/ISO)
Threonine biosynthetic process GO:0009088
The chemical reactions and pathways resulting in the formation of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.
1 O94671 (/ISO)
Homoserine biosynthetic process GO:0009090
The chemical reactions and pathways resulting in the formation of homoserine, alpha-amino-gamma-hydroxybutyric acid.
1 O94671 (/ISO)
Cellular response to osmotic stress GO:0071470
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
1 Q5B998 (/IEP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
67 F4K6Y8 (/IDA) F4K6Y8 (/IDA) P00562 (/IDA) P00562 (/IDA) P00562 (/IDA) P00562 (/IDA) P00562 (/IDA) P00562 (/IDA) P00562 (/IDA) P00562 (/IDA)
(57 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
8 P31116 (/HDA) P31116 (/HDA) P31116 (/HDA) P31116 (/HDA) P31116 (/HDA) P31116 (/HDA) P31116 (/HDA) P31116 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
8 P31116 (/HDA) P31116 (/HDA) P31116 (/HDA) P31116 (/HDA) P31116 (/HDA) P31116 (/HDA) P31116 (/HDA) P31116 (/HDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
3 O81852 (/IDA) O81852 (/IDA) Q9SA18 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
3 O81852 (/IDA) O81852 (/IDA) Q9SA18 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...