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CATH Superfamily 3.30.360.10

Dihydrodipicolinate Reductase; domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Dihydrodipicolinate Reductase; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 35: Galactose 1-dehydrogenase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
D-galactose 1-dehydrogenase. [EC: 1.1.1.48]
D-galactose + NAD(+) = D-galactono-1,4-lactone + NADH.
  • This enzyme is part of the De Ley-Doudoroff pathway, which is used by some bacteria during growth on D-galactose.
 9 A0A0B2BUY2 A0A0B2BUY2 A0A0B2BUY2 A0A1E3FHU6 A0A1E3FHU6 A0A1E3FHU6 Q53TZ2 Q53TZ2 Q53TZ2
L-arabinose 1-dehydrogenase (NAD(P)(+)). [EC: 1.1.1.376]
L-arabinose + NAD(P)(+) = L-arabinono-1,4-lactone + NAD(P)H.
  • The enzymes from the bacterium Azospirillum brasilense and the archaeon Haloferax volcanii are part of the L-arabinose degradation pathway and prefer NADP(+) over NAD(+).
  • In vitro the enzyme from Azospirillum brasilense shows also high catalytic efficiency with D-galactose.
 9 A0A0B2BUY2 A0A0B2BUY2 A0A0B2BUY2 A0A1E3FHU6 A0A1E3FHU6 A0A1E3FHU6 Q53TZ2 Q53TZ2 Q53TZ2
Galactose 1-dehydrogenase (NADP(+)). [EC: 1.1.1.120]
D-galactose + NADP(+) = D-galactono-1,5-lactone + NADPH.
  • Also acts on L-arabinose, 6-deoxy- and 2-deoxy-D-galactose.
 9 A0A0B2BUY2 A0A0B2BUY2 A0A0B2BUY2 A0A1E3FHU6 A0A1E3FHU6 A0A1E3FHU6 Q53TZ2 Q53TZ2 Q53TZ2