The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Dihydrodipicolinate Reductase; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: Glucose-6-phosphate 1-dehydrogenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glucose-6-phosphate dehydrogenase activity GO:0004345
Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+.
110 P0AC53 (/IDA) P0AC53 (/IDA) P0AC53 (/IDA) P0AC53 (/IDA) P0AC53 (/IDA) P0AC53 (/IDA) P0AC53 (/IDA) P0AC53 (/IDA) P0AC53 (/IDA) P0AC53 (/IDA)
(100 more)
Glucose-6-phosphate dehydrogenase activity GO:0004345
Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+.
110 P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP)
(100 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
110 P0AC53 (/IPI) P0AC53 (/IPI) P0AC53 (/IPI) P0AC53 (/IPI) P0AC53 (/IPI) P0AC53 (/IPI) P0AC53 (/IPI) P0AC53 (/IPI) P0AC53 (/IPI) P0AC53 (/IPI)
(100 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
110 P0AC53 (/IPI) P0AC53 (/IPI) P0AC53 (/IPI) P0AC53 (/IPI) P0AC53 (/IPI) P0AC53 (/IPI) P0AC53 (/IPI) P0AC53 (/IPI) P0AC53 (/IPI) P0AC53 (/IPI)
(100 more)
Glucose-6-phosphate dehydrogenase activity GO:0004345
Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+.
1 O14137 (/ISS)
Glucose 1-dehydrogenase (NADP+) activity GO:0047935
Catalysis of the reaction: D-glucose + NADP+ = D-glucono-1,5-lactone + NADPH.
1 O59812 (/IDA)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glucose metabolic process GO:0006006
The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.
110 P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP)
(100 more)
Pentose-phosphate shunt GO:0006098
The glucose-6-phosphate catabolic process in which, coupled to NADPH synthesis, glucose-6-P is oxidized with the formation of carbon dioxide (CO2) and ribulose 5-phosphate; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses.
110 P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP)
(100 more)
Cell-cell signaling involved in quorum sensing GO:0010699
The cell-cell signaling process in which single-celled organisms monitor population density by detecting the concentration of small diffusible signal molecules.
110 P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP) P0AC53 (/IMP)
(100 more)
Pentose-phosphate shunt, oxidative branch GO:0009051
The branch of the pentose-phosphate shunt which involves the oxidation of glucose 6-P and produces ribulose 5-P, reduced NADP+ and carbon dioxide (CO2).
1 O14137 (/IC)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
110 P0AC53 (/IDA) P0AC53 (/IDA) P0AC53 (/IDA) P0AC53 (/IDA) P0AC53 (/IDA) P0AC53 (/IDA) P0AC53 (/IDA) P0AC53 (/IDA) P0AC53 (/IDA) P0AC53 (/IDA)
(100 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
11 P9WN73 (/HDA) P9WN73 (/HDA) P9WN73 (/HDA) P9WN73 (/HDA) P9WN73 (/HDA) P9WN73 (/HDA) P9WN73 (/HDA) P9WN73 (/HDA) P9WN73 (/HDA) P9WN73 (/HDA)
(1 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 O14137 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O59812 (/HDA)
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