The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
DNA Polymerase, chain B, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: DNA polymerase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-directed DNA polymerase activity GO:0003887
Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group.
17 Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS)
(7 more)
Single-stranded DNA 3'-5' exodeoxyribonuclease activity GO:0008310
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a single-stranded DNA molecule.
17 Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS)
(7 more)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
17 Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS)
(7 more)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Delta DNA polymerase complex GO:0043625
A multimeric DNA polymerase enzyme complex which differs in composition amongst species; in humans it is a heterotetramer of four subunits of approximately 125, 50, 68 and 12kDa, while in S. cerevisiae, it has three different subunits which form a heterotrimer, and the active enzyme is a dimer of this heterotrimer. Functions in DNA replication, mismatch repair and excision repair.
17 Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS) Q7KQL4 (/ISS)
(7 more)
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