The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Kinase associated domain 1, KA1
".
FunFam 17: Non-specific serine/threonine protein kinase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
|
6 | P06782 (/HDA) P06782 (/HDA) P06782 (/HDA) P06782 (/HDA) P06782 (/HDA) P06782 (/HDA) |
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
6 | P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) |
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
6 | P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) |
AMP-activated protein kinase activity GO:0004679
Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of AMP.
|
6 | P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) |
ARF guanyl-nucleotide exchange factor activity GO:0005086
Stimulates the exchange of guanyl nucleotides associated with the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
|
6 | P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | P06782 (/IPI) P06782 (/IPI) P06782 (/IPI) P06782 (/IPI) P06782 (/IPI) P06782 (/IPI) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
6 | P06782 (/IPI) P06782 (/IPI) P06782 (/IPI) P06782 (/IPI) P06782 (/IPI) P06782 (/IPI) |
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
2 | A0A1D8PN61 (/IGI) A0A1D8PN61 (/IGI) |
There are 26 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Establishment of mitotic spindle orientation GO:0000132
A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures.
|
6 | P06782 (/IGI) P06782 (/IGI) P06782 (/IGI) P06782 (/IGI) P06782 (/IGI) P06782 (/IGI) |
Establishment of mitotic spindle orientation GO:0000132
A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures.
|
6 | P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) |
Replicative cell aging GO:0001302
The process associated with progression of the cell from its inception to the end of its lifespan that occurs as the cell continues cycles of growth and division.
|
6 | P06782 (/IGI) P06782 (/IGI) P06782 (/IGI) P06782 (/IGI) P06782 (/IGI) P06782 (/IGI) |
Replicative cell aging GO:0001302
The process associated with progression of the cell from its inception to the end of its lifespan that occurs as the cell continues cycles of growth and division.
|
6 | P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) |
Invasive growth in response to glucose limitation GO:0001403
A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae.
|
6 | P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
6 | P06782 (/HDA) P06782 (/HDA) P06782 (/HDA) P06782 (/HDA) P06782 (/HDA) P06782 (/HDA) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
6 | P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
6 | P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) |
Response to unfolded protein GO:0006986
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
|
6 | P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) |
Cellular response to nitrogen starvation GO:0006995
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen.
|
6 | P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) |
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
|
6 | P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) |
Positive regulation of macroautophagy GO:0016239
Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation.
|
6 | P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) |
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
|
6 | P06782 (/IGI) P06782 (/IGI) P06782 (/IGI) P06782 (/IGI) P06782 (/IGI) P06782 (/IGI) |
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
|
6 | P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) |
Positive regulation of gluconeogenesis GO:0045722
Any process that activates or increases the frequency, rate or extent of gluconeogenesis.
|
6 | P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) |
Fungal-type cell wall assembly GO:0071940
The aggregation, arrangement and bonding together of a set of components to form a fungal-type cell wall.
|
6 | P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) |
Single-species surface biofilm formation GO:0090606
A process in which microorganisms produce an extracellular matrix and form multicellular aggregates at an air-liquid interface.
|
6 | P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) |
Positive regulation of filamentous growth of a population of unicellular organisms in response to starvation GO:1900436
Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.
|
6 | P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) |
Positive regulation of pseudohyphal growth GO:2000222
Any process that activates or increases the frequency, rate or extent of pseudohyphal growth.
|
6 | P06782 (/IGI) P06782 (/IGI) P06782 (/IGI) P06782 (/IGI) P06782 (/IGI) P06782 (/IGI) |
Positive regulation of pseudohyphal growth GO:2000222
Any process that activates or increases the frequency, rate or extent of pseudohyphal growth.
|
6 | P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) P06782 (/IMP) |
Trehalose catabolic process GO:0005993
The chemical reactions and pathways resulting in the breakdown of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.
|
2 | Q00372 (/IMP) Q00372 (/IMP) |
Regulation of carbohydrate metabolic process GO:0006109
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.
|
2 | A0A1D8PN61 (/IGI) A0A1D8PN61 (/IGI) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
2 | Q00372 (/IGI) Q00372 (/IGI) |
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
|
2 | A0A1D8PN61 (/IMP) A0A1D8PN61 (/IMP) |
Filamentous growth of a population of unicellular organisms GO:0044182
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.
|
2 | A0A1D8PN61 (/IMP) A0A1D8PN61 (/IMP) |
Negative regulation of filamentous growth of a population of unicellular organisms GO:1900429
Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms.
|
2 | A0A1D8PN61 (/IMP) A0A1D8PN61 (/IMP) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cellular bud neck septin ring GO:0000144
A ring-shaped structure that forms at the site of cytokinesis in the bud neck of a budding cell; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins. In S. cerevisiae, this structure forms at the time of bud emergence and the septins show a high rate of exchange.
|
6 | P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) |
Fungal-type vacuole GO:0000324
A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.
|
6 | P06782 (/IPI) P06782 (/IPI) P06782 (/IPI) P06782 (/IPI) P06782 (/IPI) P06782 (/IPI) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
6 | P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) |
Nuclear envelope lumen GO:0005641
The region between the two lipid bilayers of the nuclear envelope; 20-40 nm wide.
|
6 | P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
6 | P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
6 | P06782 (/HDA) P06782 (/HDA) P06782 (/HDA) P06782 (/HDA) P06782 (/HDA) P06782 (/HDA) |
Nucleotide-activated protein kinase complex GO:0031588
A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae).
|
6 | P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) P06782 (/IDA) |
Nucleotide-activated protein kinase complex GO:0031588
A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae).
|
6 | P06782 (/IPI) P06782 (/IPI) P06782 (/IPI) P06782 (/IPI) P06782 (/IPI) P06782 (/IPI) |