The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Kinase associated domain 1, KA1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 10: Non-specific serine/threonine protein kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 P13185 (/IPI) P13186 (/IPI) P13186 (/IPI) P13186 (/IPI) P13186 (/IPI) P13186 (/IPI) P13186 (/IPI) P22987 (/IPI)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
7 P13185 (/HDA) P13186 (/HDA) P13186 (/HDA) P13186 (/HDA) P13186 (/HDA) P13186 (/HDA) P13186 (/HDA)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
7 P13185 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
1 P22987 (/EXP)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 P22987 (/ISM)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
7 P13185 (/HDA) P13186 (/HDA) P13186 (/HDA) P13186 (/HDA) P13186 (/HDA) P13186 (/HDA) P13186 (/HDA)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
7 P13185 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA)
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
7 P13185 (/IGI) P13186 (/IGI) P13186 (/IGI) P13186 (/IGI) P13186 (/IGI) P13186 (/IGI) P13186 (/IGI)
Positive regulation of exocytosis GO:0045921
Any process that activates or increases the frequency, rate or extent of exocytosis.
7 P13185 (/IGI) P13186 (/IGI) P13186 (/IGI) P13186 (/IGI) P13186 (/IGI) P13186 (/IGI) P13186 (/IGI)
Positive regulation of exocytosis GO:0045921
Any process that activates or increases the frequency, rate or extent of exocytosis.
7 P13185 (/IPI) P13186 (/IPI) P13186 (/IPI) P13186 (/IPI) P13186 (/IPI) P13186 (/IPI) P13186 (/IPI)
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
7 P13185 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA)
Positive regulation of IRE1-mediated unfolded protein response GO:1903896
Any process that activates or increases the frequency, rate or extent of the IRE1-mediated unfolded protein response.
7 P13185 (/IGI) P13186 (/IGI) P13186 (/IGI) P13186 (/IGI) P13186 (/IGI) P13186 (/IGI) P13186 (/IGI)
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
6 P13186 (/IMP) P13186 (/IMP) P13186 (/IMP) P13186 (/IMP) P13186 (/IMP) P13186 (/IMP)
Plasma membrane organization GO:0007009
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane.
1 P22987 (/IMP)
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
1 P13185 (/IDA)
Establishment or maintenance of actin cytoskeleton polarity GO:0030950
Any cellular process that results in the specification, formation or maintenance of polarized actin-based cytoskeletal structures.
1 P22987 (/IMP)
Cell growth mode switching, monopolar to bipolar GO:0051523
The process in which a cell switches from monopolar cell growth to bipolar cell growth.
1 P22987 (/IMP)
Establishment or maintenance of cell polarity regulating cell shape GO:0071963
Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell.
1 P22987 (/IMP)
Mitotic cytokinesis, site selection GO:1902408
Any cytokinesis, site selection that is involved in mitotic cell cycle.
1 P22987 (/IMP)

There are 14 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
7 P13185 (/IPI) P13186 (/IPI) P13186 (/IPI) P13186 (/IPI) P13186 (/IPI) P13186 (/IPI) P13186 (/IPI)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
6 P13186 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA)
Cellular bud tip GO:0005934
The end of a cellular bud distal to the site of attachment to the mother cell.
6 P13186 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA)
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
6 P13186 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA) P13186 (/IDA)
Cytoplasmic side of plasma membrane GO:0009898
The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
1 P13185 (/IDA)
Microtubule cytoskeleton GO:0015630
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
1 P22987 (/TAS)
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
1 P22987 (/HDA)
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
1 P22987 (/IDA)
Medial membrane band GO:0032178
A sterol-rich region of the plasma membrane which forms at the cell surface overlying the contractile ring and spreads into the invaginating plasma membrane surrounding the septum.
1 P22987 (/IDA)
Non-growing cell tip GO:0035839
A cell tip at which no growth takes place. For example, in fission yeast the cell end newly formed by cell division does not grow immediately upon its formation, and lacks actin cytoskeletal structures.
1 P22987 (/IDA)
New growing cell tip GO:0035841
A cell tip that was newly formed at the last cell division, and that has started to grow after the cell has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). New end take-off is when monopolar cells initiate bipolar growth.
1 P22987 (/IDA)
Old cell tip after activation of bipolar cell growth GO:0035842
A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs, which is part of a cell that has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures.
1 P22987 (/IDA)
Cell tip GO:0051286
The region at the end of the longest axis of a cylindrical or elongated cell.
1 P22987 (/HDA)
Intrinsic component of plasma membrane of cell tip GO:1990873
The component of the plasma membrane surrounding the cell tip consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the plasma membrane surrounding the cell tip or some other covalently attached group such as a GPI anchor that is similarly embedded in the plasma membrane surrounding the cell tip.
1 P22987 (/IDA)
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