The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ubiquitin-related
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: Ubiquitin-like-specific protease 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
SUMO-specific isopeptidase activity GO:0070140
Catalysis of the hydrolysis of an isopeptide bond between the small conjugating protein SUMO and a protein to which SUMO has been conjugated.
2 A0A1D8PSK4 (/IDA) Q02724 (/IDA)
Cysteine-type peptidase activity GO:0008234
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
1 Q02724 (/IDA)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
1 Q02724 (/IDA)
SUMO-specific isopeptidase activity GO:0070140
Catalysis of the hydrolysis of an isopeptide bond between the small conjugating protein SUMO and a protein to which SUMO has been conjugated.
1 Q02724 (/IMP)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein desumoylation GO:0016926
The process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.
2 A0A1D8PSK4 (/IDA) Q02724 (/IDA)
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
1 Q02724 (/IMP)
Protein desumoylation GO:0016926
The process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.
1 Q02724 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
1 Q02724 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 Q02724 (/IDA)
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