The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Fe-S cluster assembly (FSCA)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: cytosolic iron-sulfur assembly component 2A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
13 O62252 (/IPI) Q9DCL2 (/IPI) Q9H5X1 (/IPI) Q9H5X1 (/IPI) Q9H5X1 (/IPI) Q9H5X1 (/IPI) Q9H5X1 (/IPI) Q9H5X1 (/IPI) Q9H5X1 (/IPI) Q9H5X1 (/IPI)
(3 more)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Iron-sulfur cluster assembly GO:0016226
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
11 Q9H5X1 (/IMP) Q9H5X1 (/IMP) Q9H5X1 (/IMP) Q9H5X1 (/IMP) Q9H5X1 (/IMP) Q9H5X1 (/IMP) Q9H5X1 (/IMP) Q9H5X1 (/IMP) Q9H5X1 (/IMP) Q9H5X1 (/IMP)
(1 more)
Protein maturation by iron-sulfur cluster transfer GO:0097428
The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.
11 Q9H5X1 (/IMP) Q9H5X1 (/IMP) Q9H5X1 (/IMP) Q9H5X1 (/IMP) Q9H5X1 (/IMP) Q9H5X1 (/IMP) Q9H5X1 (/IMP) Q9H5X1 (/IMP) Q9H5X1 (/IMP) Q9H5X1 (/IMP)
(1 more)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
3 G4N747 (/ISS) G4N747 (/ISS) G4N747 (/ISS)
Iron-sulfur cluster assembly GO:0016226
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
3 Q3T0U7 (/ISS) Q54QK1 (/ISS) Q9DCL2 (/ISS)
Protein maturation by iron-sulfur cluster transfer GO:0097428
The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.
3 Q3T0U7 (/ISS) Q54QK1 (/ISS) Q9DCL2 (/ISS)
Nuclear chromosome segregation GO:0098813
The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
2 Q9V968 (/IMP) Q9V968 (/IMP)
Iron-sulfur cluster assembly GO:0016226
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
1 Q9DCL2 (/ISO)
Cellular response to UV GO:0034644
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
1 Q6PBY9 (/IMP)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
1 Q6PBY9 (/IMP)
Protein maturation by iron-sulfur cluster transfer GO:0097428
The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.
1 Q9DCL2 (/ISO)
Protein maturation by [4Fe-4S] cluster transfer GO:0106035
The transfer of an assembled 4Fe-4S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.
1 Q9UTL0 (/ISO)
Positive regulation of response to DNA damage stimulus GO:2001022
Any process that activates or increases the frequency, rate or extent of response to DNA damage stimulus.
1 Q6PBY9 (/IMP)

There are 15 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
15 Q57YF8 (/IDA) Q57YF8 (/IDA) Q57YF8 (/IDA) Q57YF8 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA)
(5 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
15 Q57YF8 (/IDA) Q57YF8 (/IDA) Q57YF8 (/IDA) Q57YF8 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA)
(5 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
11 Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA)
(1 more)
CIA complex GO:0097361
The cytosolic iron-sulfur protein assembly (CIA) complex mediates the incorporation of iron-sulfur clusters into apoproteins involved in DNA metabolism and genomic integrity.
11 Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA) Q9H5X1 (/IDA)
(1 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q57YF8 (/IDA) Q57YF8 (/IDA) Q57YF8 (/IDA) Q57YF8 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 G4N747 (/ISS) G4N747 (/ISS) G4N747 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 G4N747 (/ISS) G4N747 (/ISS) G4N747 (/ISS)
CIA complex GO:0097361
The cytosolic iron-sulfur protein assembly (CIA) complex mediates the incorporation of iron-sulfur clusters into apoproteins involved in DNA metabolism and genomic integrity.
3 Q3T0U7 (/ISS) Q54QK1 (/ISS) Q9DCL2 (/ISS)
Spindle microtubule GO:0005876
Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.
2 Q9V968 (/IDA) Q9V968 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9UTL0 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9DCL2 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q9DCL2 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9UTL0 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9DCL2 (/ISO)
CIA complex GO:0097361
The cytosolic iron-sulfur protein assembly (CIA) complex mediates the incorporation of iron-sulfur clusters into apoproteins involved in DNA metabolism and genomic integrity.
1 Q9DCL2 (/ISO)
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