The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Fe-S cluster assembly (FSCA)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Fe/S biogenesis protein NfuA

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
194 P63020 (/IPI) P63020 (/IPI) P63020 (/IPI) P63020 (/IPI) P63020 (/IPI) P63020 (/IPI) P63020 (/IPI) P63020 (/IPI) P63020 (/IPI) P63020 (/IPI)
(184 more)
4 iron, 4 sulfur cluster binding GO:0051539
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
194 P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA)
(184 more)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
194 P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP)
(184 more)
Cellular response to iron ion starvation GO:0010106
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions.
194 P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP)
(184 more)
Carbon utilization GO:0015976
A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing substances, and ends when carbon is incorporated into the cell or organism's metabolism.
194 P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP)
(184 more)
Iron-sulfur cluster assembly GO:0016226
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
194 P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA)
(184 more)
Iron-sulfur cluster assembly GO:0016226
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
194 P63020 (/IGI) P63020 (/IGI) P63020 (/IGI) P63020 (/IGI) P63020 (/IGI) P63020 (/IGI) P63020 (/IGI) P63020 (/IGI) P63020 (/IGI) P63020 (/IGI)
(184 more)
Iron-sulfur cluster assembly GO:0016226
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
194 P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP) P63020 (/IMP)
(184 more)
Protein maturation by iron-sulfur cluster transfer GO:0097428
The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.
194 P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA)
(184 more)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
194 P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA) P63020 (/IDA)
(184 more)
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