The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: GMP synthase [glutamine-hydrolyzing]

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GMP synthase (glutamine-hydrolyzing) activity GO:0003922
Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H(+).
3 Q4V7C6 (/IDA) Q57V01 (/IDA) Q57V01 (/IDA)
GMP synthase activity GO:0003921
Catalysis of the reaction: ATP + XMP + NH4(+) = AMP + diphosphate + GMP + 2H(+).
2 Q3THK7 (/ISO) Q3THK7 (/ISO)
GMP synthase activity GO:0003921
Catalysis of the reaction: ATP + XMP + NH4(+) = AMP + diphosphate + GMP + 2H(+).
2 P49915 (/TAS) P49915 (/TAS)
GMP synthase (glutamine-hydrolyzing) activity GO:0003922
Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H(+).
2 P49915 (/EXP) P49915 (/EXP)
GMP synthase activity GO:0003921
Catalysis of the reaction: ATP + XMP + NH4(+) = AMP + diphosphate + GMP + 2H(+).
1 Q4V7C6 (/IDA)
GMP synthase (glutamine-hydrolyzing) activity GO:0003922
Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H(+).
1 Q4QBY3 (/ISO)
GMP synthase (glutamine-hydrolyzing) activity GO:0003922
Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H(+).
1 P32073 (/ISS)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 Q4V7C6 (/IDA)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GMP biosynthetic process GO:0006177
The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate.
2 Q3THK7 (/ISO) Q3THK7 (/ISO)
Purine nucleobase biosynthetic process GO:0009113
The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
2 P49915 (/TAS) P49915 (/TAS)
Purine ribonucleotide biosynthetic process GO:0009152
The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
2 Q57V01 (/TAS) Q57V01 (/TAS)
Purine ribonucleoside monophosphate biosynthetic process GO:0009168
The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.
2 P49915 (/TAS) P49915 (/TAS)
GMP salvage GO:0032263
Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis.
2 Q57V01 (/IDA) Q57V01 (/IDA)
GMP biosynthetic process GO:0006177
The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate.
1 Q4V7C6 (/IDA)
GMP biosynthetic process GO:0006177
The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate.
1 P32073 (/ISS)
GMP salvage GO:0032263
Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis.
1 Q4QBY3 (/ISO)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 Q4V7C6 (/IEP)
GMP metabolic process GO:0046037
The chemical reactions and pathways involving GMP, guanosine monophosphate.
1 P32073 (/ISS)
Response to L-cysteine GO:1901367
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus.
1 Q4V7C6 (/IDA)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 A0A140VJK6 (/IDA) A0A140VJK6 (/IDA) P49915 (/IDA) P49915 (/IDA) Q4V7C6 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q57V01 (/IDA) Q57V01 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q3THK7 (/ISO) Q3THK7 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P49915 (/TAS) P49915 (/TAS)
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
1 P32073 (/HDA)
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