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CATH Superfamily 3.30.30.120

Diapause-specific peptide

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Diapause-specific peptide
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Diapause-specific peptide

This superfamily includes the diapause-specific peptides (DSP). Diapause during periods of environmental adversity is an essential part of the life cycle of many organisms with the molecular basis being different among animals. Diapause-specific peptides function as anti-fungal peptides and block N-type voltage-gated calcium channels PMID:14706547. The overall structure of DSP is compact due to the three disulfide bridges that indicate a high similarity with insect- and plant-derived antifungal peptides.

The DSP structure includes two alpha-helices and a triple-stranded beta-sheet. The three disulfide bridges (Cys-7/Cys-21, Cys-11/Cys-33, and Cys-22/Cys-40) help the link between helices and the beta-sheets.

PFAM:PF08036, INTERPRO:IPR012525,DOI:10.1021/bi701319t

GO Diversity

Unique GO annotations
3 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
10 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 1
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 1
Function
Unique EC:
Unique GO: 3
Taxonomy
Unique Species: 10