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CATH Superfamily 3.30.2440.10

Secreted effector protein SifA

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Secreted effector protein SifA
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: SPI-2 type III secretion system effector SseJ

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 54 A0A0F6B1Q8 (/IPI) A0A0F6B1Q8 (/IPI) A0A0F6B1Q8 (/IPI) A0A0F6B1Q8 (/IPI) A0A0F6B1Q8 (/IPI) A0A0F6B1Q8 (/IPI) A0A0F6B1Q8 (/IPI) A0A0F6B1Q8 (/IPI) A0A0F6B1Q8 (/IPI) A0A0F6B1Q8 (/IPI)
(44 more)
Lipase activity GO:0016298
Catalysis of the hydrolysis of a lipid or phospholipid.
 27 Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA)
(17 more)
Rho GTPase binding GO:0017048
Interacting selectively and non-covalently with Rho protein, any member of the Rho subfamily of the Ras superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton.
 27 Q9FD10 (/IPI) Q9FD10 (/IPI) Q9FD10 (/IPI) Q9FD10 (/IPI) Q9FD10 (/IPI) Q9FD10 (/IPI) Q9FD10 (/IPI) Q9FD10 (/IPI) Q9FD10 (/IPI) Q9FD10 (/IPI)
(17 more)
Cholesterol O-acyltransferase activity GO:0034736
Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA.
 27 Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA)
(17 more)
Glycerophospholipid acyltransferase (CoA-dependent) activity GO:0047178
Catalysis of the reaction: 1-radyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-radyl-2-acyl-sn-glycero-3-phosphocholine = 1-radyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acyl-sn-glycero-3-phosphoethanolamine.
 27 Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA) Q9FD10 (/IDA)
(17 more)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of membrane tubulation GO:1903527
Any process that activates or increases the frequency, rate or extent of membrane tubulation.
 27 A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA)
(17 more)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Host cell plasma membrane GO:0020002
The plasma membrane surrounding a host cell.
 27 A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA)
(17 more)
Host cell membrane GO:0033644
Double layer of lipid molecules as it encloses host cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction.
 27 Q9FD10 (/IMP) Q9FD10 (/IMP) Q9FD10 (/IMP) Q9FD10 (/IMP) Q9FD10 (/IMP) Q9FD10 (/IMP) Q9FD10 (/IMP) Q9FD10 (/IMP) Q9FD10 (/IMP) Q9FD10 (/IMP)
(17 more)
Host cell endosome GO:0044174
A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to host cell lysosomes for degradation.
 27 Q9FD10 (/IMP) Q9FD10 (/IMP) Q9FD10 (/IMP) Q9FD10 (/IMP) Q9FD10 (/IMP) Q9FD10 (/IMP) Q9FD10 (/IMP) Q9FD10 (/IMP) Q9FD10 (/IMP) Q9FD10 (/IMP)
(17 more)
Host cell late endosome GO:0044184
A prelysosomal endocytic organelle differentiated from host early endosomes by lower lumenal pH and different protein composition. Host late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
 27 A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA) A0A0F6B1Q8 (/IDA)
(17 more)
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