The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
E6 early regulatory protein
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Protein E6

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
54 P03126 (/IPI) P03126 (/IPI) P03126 (/IPI) P03126 (/IPI) P03126 (/IPI) P03126 (/IPI) P03126 (/IPI) P06463 (/IPI) P06463 (/IPI) P06463 (/IPI)
(44 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
34 P06463 (/IDA) P06463 (/IDA) P06463 (/IDA) P06463 (/IDA) P06463 (/IDA) P06463 (/IDA) P06463 (/IDA) P06463 (/IDA) P06463 (/IDA) P06463 (/IDA)
(24 more)
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
7 P03126 (/IPI) P03126 (/IPI) P03126 (/IPI) P03126 (/IPI) P03126 (/IPI) P03126 (/IPI) P03126 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
7 P03126 (/IPI) P03126 (/IPI) P03126 (/IPI) P03126 (/IPI) P03126 (/IPI) P03126 (/IPI) P03126 (/IPI)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
34 P06463 (/IDA) P06463 (/IDA) P06463 (/IDA) P06463 (/IDA) P06463 (/IDA) P06463 (/IDA) P06463 (/IDA) P06463 (/IDA) P06463 (/IDA) P06463 (/IDA)
(24 more)
Suppression by virus of host transcription GO:0039653
Any process in which a virus stops, prevents, or reduces the activity of host DNA-dependent transcription; the cellular synthesis of RNA on a template of DNA. Viral proteins can interfere with either host RNA polymerase or with transcription factors.
7 P03126 (/IMP) P03126 (/IMP) P03126 (/IMP) P03126 (/IMP) P03126 (/IMP) P03126 (/IMP) P03126 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
7 P03126 (/IDA) P03126 (/IDA) P03126 (/IDA) P03126 (/IDA) P03126 (/IDA) P03126 (/IDA) P03126 (/IDA)
Activation of GTPase activity GO:0090630
Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
7 P03126 (/IDA) P03126 (/IDA) P03126 (/IDA) P03126 (/IDA) P03126 (/IDA) P03126 (/IDA) P03126 (/IDA)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Host cell nucleus GO:0042025
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
9 Q1AHS5 (/IDA) Q2VJD5 (/IDA) Q2VJD5 (/IDA) Q2VJD5 (/IDA) Q81964 (/IDA) Q81964 (/IDA) Q82005 (/IDA) Q9IR59 (/IDA) Q9WNN0 (/IDA)
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