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CATH Superfamily 3.30.2130.10

VC0802-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
VC0802-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Bifunctional aspartokinase/homoserine dehydrogenas...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Aspartate kinase. [EC: 2.7.2.4]
ATP + L-aspartate = ADP + 4-phospho-L-aspartate.
  • The enzyme from Escherichia coli is a multifunctional protein, which also catalyzes the reaction of EC 1.1.1.3.
  • This is also the case for two of the four isoenzymes in Arabidopsis thaliana.
  • The equilibrium constant strongly favors the reaction from right to left, i.e. the non-physiological direction of reaction.
 922 A0A0E0V055 A0A0E0V055 A0A0E0V055 A0A0E0V055 A0A0E0V055 A0A0E0V055 A0A0E0V055 A0A0E0V055 A0A0E0V055 A0A0E0V055
(912 more...)
Homoserine dehydrogenase. [EC: 1.1.1.3]
L-homoserine + NAD(P)(+) = L-aspartate 4-semialdehyde + NAD(P)H.
  • The enzyme from Saccharomyces cerevisiae acts most rapidly with NAD(+); the Neurospora enzyme with NADP(+).
  • The enzyme from Escherichia coli is a multifunctional protein, which also catalyzes the reaction of EC 2.7.2.4.
 826 A0A0E0V055 A0A0E0V055 A0A0E0V055 A0A0E0V055 A0A0E0V055 A0A0E0V055 A0A0E0V055 A0A0E0V055 A0A0E0V055 A0A0E0V055
(816 more...)