View in Gene3D

CATH Superfamily 3.30.2010.30

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 2: Putative aminopeptidase N

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Membrane alanyl aminopeptidase. [EC: 3.4.11.2]
Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.
  • Is not activated by heavy metal ions.
  • Belongs to peptidase family M1.
  • Formerly EC 3.4.1.2, EC 3.4.3.5 and EC 3.4.13.6.
 362 A0A024L4E3 A0A024L4E3 A0A024L4E3 A0A024L4E3 A0A024L4E3 A0A024L4E3 A0A024L4E3 A0A024L4E3 A0A024L4E3 A0A024L4E3
(352 more...)
Cytosol alanyl aminopeptidase. [EC: 3.4.11.14]
Release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides.
  • A puromycin-sensitive, cobalt-activated zinc-sialoglycoprotein that is generally cytosolic.
  • Multiple forms are widely distributed in mammalian tissues and body fluids.
 2 B7EA73 Q8H0S9
CATH-Gene3D is a Global Biodata Core Resource Learn more...