The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Metalloproteases ("zincins"), catalytic domain
".
FunFam 1: Protease HtpX
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Metalloendopeptidase activity GO:0004222
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
|
9 | P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
9 | P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
11 |
Q608V6 (/ISS)
Q8EDL5 (/ISS)
Q9KSY9 (/ISS)
Q9KSY9 (/ISS)
Q9KSY9 (/ISS)
Q9KSY9 (/ISS)
Q9KSY9 (/ISS)
Q9KSY9 (/ISS)
Q9KSY9 (/ISS)
Q9KSY9 (/ISS)
(1 more) |
|
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
|
9 | P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) |
|
Response to temperature stimulus GO:0009266
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.
|
9 | P23894 (/IEP) P23894 (/IEP) P23894 (/IEP) P23894 (/IEP) P23894 (/IEP) P23894 (/IEP) P23894 (/IEP) P23894 (/IEP) P23894 (/IEP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
9 | P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
9 | P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) P23894 (/IDA) |
