The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphorylase Kinase; domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 91: Serine/threonine-protein kinase PLK

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 19 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
16 P32562 (/IPI) P32562 (/IPI) P32562 (/IPI) P32562 (/IPI) P32562 (/IPI) P34331 (/IPI) Q60806 (/IPI) Q9H4B4 (/IPI) Q9N2L7 (/IPI) Q9NYY3 (/IPI)
(6 more)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
10 P53351 (/IDA) P53351 (/IDA) Q60806 (/IDA) Q9H4B4 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9R012 (/IDA)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
6 P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P34331 (/IDA)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
6 Q9H4B4 (/TAS) Q9NYY3 (/TAS) Q9NYY3 (/TAS) Q9NYY3 (/TAS) Q9NYY3 (/TAS) Q9NYY3 (/TAS)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
6 P32562 (/IPI) P32562 (/IPI) P32562 (/IPI) P32562 (/IPI) P32562 (/IPI) Q9R012 (/IPI)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
5 P32562 (/HDA) P32562 (/HDA) P32562 (/HDA) P32562 (/HDA) P32562 (/HDA)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
5 P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP)
Centromeric DNA binding GO:0019237
Interacting selectively and non-covalently with a centromere, a region of chromosome where the spindle fibers attach during mitosis and meiosis.
5 P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA)
ATP-dependent protein binding GO:0043008
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) using energy from the hydrolysis of ATP.
5 Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA)
Phosphoprotein binding GO:0051219
Interacting selectively and non-covalently with a phosphorylated protein.
5 P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
3 P53351 (/ISO) P53351 (/ISO) Q60806 (/ISO)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
3 P34331 (/ISS) Q86HN7 (/ISS) Q9R011 (/ISS)
P53 binding GO:0002039
Interacting selectively and non-covalently with one of the p53 family of proteins.
2 Q60806 (/ISS) Q9R011 (/ISS)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
2 C8VMZ9 (/ISS) C8VMZ9 (/ISS)
ATP-dependent protein binding GO:0043008
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) using energy from the hydrolysis of ATP.
2 P53351 (/ISO) P53351 (/ISO)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
2 P53351 (/ISO) P53351 (/ISO)
P53 binding GO:0002039
Interacting selectively and non-covalently with one of the p53 family of proteins.
1 Q9H4B4 (/IDA)
P53 binding GO:0002039
Interacting selectively and non-covalently with one of the p53 family of proteins.
1 Q60806 (/ISO)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
1 Q9R011 (/TAS)

There are 139 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
15 P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P34331 (/IDA) P53351 (/IDA) P53351 (/IDA) Q60806 (/IDA) Q9NYY3 (/IDA)
(5 more)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
10 Q5R4L1 (/ISS) Q5R4L1 (/ISS) Q60806 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9R011 (/ISS) Q9R012 (/ISS)
Ras protein signal transduction GO:0007265
A series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state.
9 P53351 (/ISS) P53351 (/ISS) Q5R4L1 (/ISS) Q5R4L1 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS)
Rap protein signal transduction GO:0032486
A series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state.
9 P53351 (/ISS) P53351 (/ISS) Q5R4L1 (/ISS) Q5R4L1 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS)
Long-term synaptic potentiation GO:0060291
A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse.
9 P53351 (/ISS) P53351 (/ISS) Q5R4L1 (/ISS) Q5R4L1 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS)
Long-term synaptic depression GO:0060292
A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse.
9 P53351 (/ISS) P53351 (/ISS) Q5R4L1 (/ISS) Q5R4L1 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS)
Mitotic cell cycle checkpoint GO:0007093
A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.
8 Q5R4L1 (/ISS) Q5R4L1 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9R012 (/ISS)
Memory GO:0007613
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
8 Q5R4L1 (/ISS) Q5R4L1 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9R012 (/ISS)
G1/S transition of mitotic cell cycle GO:0000082
The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
7 P53351 (/ISS) P53351 (/ISS) Q5R4L1 (/ISS) Q5R4L1 (/ISS) Q60806 (/ISS) Q9R011 (/ISS) Q9R012 (/ISS)
Regulation of synaptic plasticity GO:0048167
A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
7 Q5R4L1 (/ISS) Q5R4L1 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS)
G1/S transition of mitotic cell cycle GO:0000082
The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
6 Q9H4B4 (/IMP) Q9NYY3 (/IMP) Q9NYY3 (/IMP) Q9NYY3 (/IMP) Q9NYY3 (/IMP) Q9NYY3 (/IMP)
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle.
6 Q9H4B4 (/TAS) Q9NYY3 (/TAS) Q9NYY3 (/TAS) Q9NYY3 (/TAS) Q9NYY3 (/TAS) Q9NYY3 (/TAS)
Resolution of meiotic recombination intermediates GO:0000712
The cleavage and rejoining of intermediates, such as Holliday junctions, formed during meiotic recombination to produce two intact molecules in which genetic material has been exchanged.
5 P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
5 P32562 (/HDA) P32562 (/HDA) P32562 (/HDA) P32562 (/HDA) P32562 (/HDA)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
5 P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
5 P32562 (/IPI) P32562 (/IPI) P32562 (/IPI) P32562 (/IPI) P32562 (/IPI)
Mitotic spindle organization GO:0007052
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
5 Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA)
Mitotic spindle organization GO:0007052
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
5 P53351 (/ISS) P53351 (/ISS) Q5R4L1 (/ISS) Q5R4L1 (/ISS) Q9R012 (/ISS)
Exit from mitosis GO:0010458
The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
5 P32562 (/IGI) P32562 (/IGI) P32562 (/IGI) P32562 (/IGI) P32562 (/IGI)
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
5 Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA)
Positive regulation of mitotic spindle pole body separation GO:0010696
Any process that increases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.
5 P32562 (/IGI) P32562 (/IGI) P32562 (/IGI) P32562 (/IGI) P32562 (/IGI)
Positive regulation of mitotic spindle pole body separation GO:0010696
Any process that increases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.
5 P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP)
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
5 Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA)
Positive regulation of Rho protein signal transduction GO:0035025
Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction.
5 P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP)
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
5 Q9NYY3 (/HMP) Q9NYY3 (/HMP) Q9NYY3 (/HMP) Q9NYY3 (/HMP) Q9NYY3 (/HMP)
Positive regulation of protein catabolic process GO:0045732
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
5 Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA)
Regulation of centriole replication GO:0046599
Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole.
5 Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA)
Regulation of centriole replication GO:0046599
Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole.
5 Q9NYY3 (/IMP) Q9NYY3 (/IMP) Q9NYY3 (/IMP) Q9NYY3 (/IMP) Q9NYY3 (/IMP)
Regulation of centriole replication GO:0046599
Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole.
5 P53351 (/ISS) P53351 (/ISS) Q5R4L1 (/ISS) Q5R4L1 (/ISS) Q9R012 (/ISS)
Synaptonemal complex disassembly GO:0070194
The controlled breakdown of a synaptonemal complex.
5 P32562 (/IGI) P32562 (/IGI) P32562 (/IGI) P32562 (/IGI) P32562 (/IGI)
Spindle assembly involved in meiosis GO:0090306
The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis.
5 P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP)
Positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly GO:0110083
Any process that activates or increases the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.
5 P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP)
Regulation of protein localization to mitotic spindle pole body GO:1902542
Any process that modulates the frequency, rate or extent of protein localization to mitotic spindle pole body.
5 P32562 (/IGI) P32562 (/IGI) P32562 (/IGI) P32562 (/IGI) P32562 (/IGI)
Regulation of nucleus organization GO:1903353
Any process that modulates the frequency, rate or extent of nucleus organization.
5 P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP)
G1/S transition of mitotic cell cycle GO:0000082
The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
3 P53351 (/ISO) P53351 (/ISO) Q60806 (/ISO)
Signal transduction involved in filamentous growth GO:0001402
Relaying of environmental signals promoting filamentous growth.
3 Q5ABG0 (/IMP) Q5ABG0 (/IMP) Q5ABG0 (/IMP)
Sprouting angiogenesis GO:0002040
The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation.
3 A6H8T5 (/IMP) A8WHV5 (/IMP) D9IWE4 (/IMP)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
3 Q5ABG0 (/IMP) Q5ABG0 (/IMP) Q5ABG0 (/IMP)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
3 Q5ABG0 (/IMP) Q5ABG0 (/IMP) Q5ABG0 (/IMP)
Filamentous growth of a population of unicellular organisms in response to starvation GO:0036170
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
3 Q5ABG0 (/IMP) Q5ABG0 (/IMP) Q5ABG0 (/IMP)
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
3 Q5ABG0 (/IMP) Q5ABG0 (/IMP) Q5ABG0 (/IMP)
Filamentous growth of a population of unicellular organisms GO:0044182
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.
3 Q5ABG0 (/IMP) Q5ABG0 (/IMP) Q5ABG0 (/IMP)
Regulation of synaptic plasticity GO:0048167
A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
3 P53351 (/IMP) P53351 (/IMP) Q9R012 (/IMP)
Mitotic spindle elongation GO:0000022
The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B.
2 C8VMZ9 (/IMP) C8VMZ9 (/IMP)
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
2 C8VMZ9 (/IMP) C8VMZ9 (/IMP)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 Q60806 (/ISS) Q9R011 (/ISS)
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
2 P53351 (/IMP) P53351 (/IMP)
Response to reactive oxygen species GO:0000302
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
2 Q60806 (/ISS) Q9R011 (/ISS)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
2 P53351 (/ISO) P53351 (/ISO)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
2 C8VMZ9 (/ISS) C8VMZ9 (/ISS)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
2 Q9H4B4 (/TAS) Q9R011 (/TAS)
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
2 Q60806 (/ISS) Q9R011 (/ISS)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
2 Q60806 (/IMP) Q9H4B4 (/IMP)
Mitotic spindle organization GO:0007052
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
2 P53351 (/ISO) P53351 (/ISO)
Chromosome segregation GO:0007059
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
2 C8VMZ9 (/IMP) C8VMZ9 (/IMP)
Mitotic cell cycle checkpoint GO:0007093
A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.
2 P53351 (/IMP) P53351 (/IMP)
Ras protein signal transduction GO:0007265
A series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state.
2 P53351 (/ISO) P53351 (/ISO)
Memory GO:0007613
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
2 P53351 (/IMP) P53351 (/IMP)
Response to radiation GO:0009314
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
2 Q60806 (/ISS) Q9R011 (/ISS)
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
2 P53351 (/ISO) P53351 (/ISO)
Negative regulation of angiogenesis GO:0016525
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
2 P53351 (/IMP) P53351 (/IMP)
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
2 P53351 (/ISO) P53351 (/ISO)
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
2 C8VMZ9 (/IMP) C8VMZ9 (/IMP)
Cytoplasmic microtubule organization GO:0031122
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.
2 Q60806 (/ISS) Q9R011 (/ISS)
Positive regulation of protein binding GO:0032092
Any process that activates or increases the frequency, rate or extent of protein binding.
2 P53351 (/ISO) P53351 (/ISO)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436
Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2 P53351 (/ISO) P53351 (/ISO)
Rap protein signal transduction GO:0032486
A series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state.
2 P53351 (/ISO) P53351 (/ISO)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
2 P53351 (/IMP) P53351 (/IMP)
Protein kinase B signaling GO:0043491
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.
2 Q9H4B4 (/ISS) Q9R011 (/ISS)
Asexual sporulation resulting in formation of a cellular spore GO:0043936
The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
2 C8VMZ9 (/IMP) C8VMZ9 (/IMP)
Mitotic G1/S transition checkpoint GO:0044819
A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase as part of a mitotic cell cycle.
2 Q9H4B4 (/ISS) Q9R011 (/ISS)
Positive regulation of protein catabolic process GO:0045732
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2 P53351 (/ISO) P53351 (/ISO)
Regulation of centriole replication GO:0046599
Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole.
2 P53351 (/ISO) P53351 (/ISO)
Regulation of synaptic plasticity GO:0048167
A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
2 P53351 (/ISO) P53351 (/ISO)
Regulation of synaptic plasticity GO:0048167
A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
2 Q9R011 (/TAS) Q9R012 (/TAS)
Regulation of cell division GO:0051302
Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.
2 Q60806 (/ISS) Q9R011 (/ISS)
Long-term synaptic potentiation GO:0060291
A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse.
2 P53351 (/ISO) P53351 (/ISO)
Long-term synaptic depression GO:0060292
A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse.
2 P53351 (/ISO) P53351 (/ISO)
Negative regulation of dendritic spine development GO:0061000
Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
2 P53351 (/ISO) P53351 (/ISO)
Negative regulation of apoptotic process in bone marrow cell GO:0071866
Any process that stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.
2 P53351 (/IMP) P53351 (/IMP)
Positive regulation of cell migration involved in sprouting angiogenesis GO:0090050
Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.
2 P53351 (/IMP) P53351 (/IMP)
Golgi disassembly GO:0090166
A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance.
2 Q60806 (/ISS) Q9R011 (/ISS)
Positive regulation of intracellular protein transport GO:0090316
Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells.
2 Q60806 (/ISS) Q9R011 (/ISS)
Negative regulation of cellular senescence GO:2000773
Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence.
2 P53351 (/IMP) P53351 (/IMP)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia GO:2000777
Any positive regulation of proteasomal ubiquitin-dependent protein catabolic process that is involved in a cellular response to hypoxia.
2 Q60806 (/ISS) Q9R011 (/ISS)
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
1 Q9H4B4 (/TAS)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
1 Q9H4B4 (/IDA)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
1 Q60806 (/ISO)
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
1 Q86HN7 (/ISS)
Response to reactive oxygen species GO:0000302
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
1 Q9H4B4 (/IDA)
Response to reactive oxygen species GO:0000302
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
1 Q60806 (/ISO)
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
1 Q9H4B4 (/TAS)
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
1 Q9H4B4 (/IDA)
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
1 Q60806 (/ISO)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
1 Q9H4B4 (/IDA)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
1 Q60806 (/ISO)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
1 Q9R011 (/ISS)
Mitotic spindle organization GO:0007052
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
1 P34331 (/IMP)
Mitotic nuclear envelope disassembly GO:0007077
The cell cycle process in which the controlled breakdown of the nuclear envelope during mitotic cell division occurs.
1 P34331 (/IMP)
Mitotic nuclear envelope disassembly GO:0007077
The cell cycle process in which the controlled breakdown of the nuclear envelope during mitotic cell division occurs.
1 P34331 (/TAS)
Mitotic cell cycle checkpoint GO:0007093
A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.
1 Q9H4B4 (/TAS)
Centrosome cycle GO:0007098
The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.
1 P34331 (/IMP)
Endomitotic cell cycle GO:0007113
A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.
1 Q9H4B4 (/TAS)
Female meiosis II GO:0007147
The cell cycle process in which the second meiotic division occurs in the female germline.
1 P34331 (/IMP)
Ras protein signal transduction GO:0007265
A series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state.
1 Q9R012 (/IDA)
Response to radiation GO:0009314
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
1 Q9H4B4 (/IDA)
Response to radiation GO:0009314
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
1 Q60806 (/ISO)
Cytoplasmic microtubule organization GO:0031122
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.
1 Q9H4B4 (/IMP)
Cytoplasmic microtubule organization GO:0031122
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.
1 Q60806 (/ISO)
Positive regulation of protein binding GO:0032092
Any process that activates or increases the frequency, rate or extent of protein binding.
1 Q9R012 (/IDA)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436
Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
1 Q9R012 (/IMP)
Regulation of cytokinesis GO:0032465
Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.
1 Q9H4B4 (/IMP)
Regulation of cytokinesis GO:0032465
Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.
1 Q60806 (/ISO)
Regulation of cytokinesis GO:0032465
Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.
1 Q9H4B4 (/TAS)
Rap protein signal transduction GO:0032486
A series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state.
1 Q9R012 (/IDA)
Polar body extrusion after meiotic divisions GO:0040038
The cell cycle process in which two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes.
1 P34331 (/IMP)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q9H4B4 (/IDA)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q60806 (/ISO)
Protein kinase B signaling GO:0043491
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.
1 Q60806 (/IMP)
Mitotic G1/S transition checkpoint GO:0044819
A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase as part of a mitotic cell cycle.
1 Q60806 (/IMP)
Meiotic chromosome segregation GO:0045132
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle.
1 P34331 (/IMP)
Regulation of synaptic plasticity GO:0048167
A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
1 Q9R012 (/IDA)
Regulation of long-term neuronal synaptic plasticity GO:0048169
A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.
1 Q9R011 (/NAS)
Regulation of cell division GO:0051302
Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.
1 Q9H4B4 (/IDA)
Regulation of cell division GO:0051302
Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.
1 Q60806 (/ISO)
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
1 P34331 (/IMP)
Long-term synaptic potentiation GO:0060291
A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse.
1 Q9R012 (/IDA)
Long-term synaptic depression GO:0060292
A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse.
1 Q9R012 (/IDA)
Regulation of meiosis I GO:0060631
Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
1 Q9N2L7 (/IMP)
Negative regulation of dendritic spine development GO:0061000
Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
1 Q9R012 (/IMP)
Golgi disassembly GO:0090166
A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance.
1 Q9H4B4 (/IDA)
Golgi disassembly GO:0090166
A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance.
1 Q60806 (/ISO)
Positive regulation of intracellular protein transport GO:0090316
Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells.
1 Q9H4B4 (/IMP)
Positive regulation of intracellular protein transport GO:0090316
Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells.
1 Q60806 (/ISO)
Regulation of signal transduction by p53 class mediator GO:1901796
Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.
1 Q9H4B4 (/TAS)
Positive regulation of chaperone-mediated autophagy GO:1904716
Any process that activates or increases the frequency, rate or extent of chaperone-mediated autophagy.
1 Q9H4B4 (/IDA)
Positive regulation of chaperone-mediated autophagy GO:1904716
Any process that activates or increases the frequency, rate or extent of chaperone-mediated autophagy.
1 Q60806 (/ISO)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia GO:2000777
Any positive regulation of proteasomal ubiquitin-dependent protein catabolic process that is involved in a cellular response to hypoxia.
1 Q9H4B4 (/IDA)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia GO:2000777
Any positive regulation of proteasomal ubiquitin-dependent protein catabolic process that is involved in a cellular response to hypoxia.
1 Q60806 (/ISO)

There are 34 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
9 C8VMZ9 (/IDA) C8VMZ9 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P34331 (/IDA) Q9H4B4 (/IDA)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
9 P53351 (/ISS) P53351 (/ISS) Q5R4L1 (/ISS) Q5R4L1 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS) Q9NYY3 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
8 P34331 (/IDA) Q9H4B4 (/IDA) Q9N2L7 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
8 P34331 (/IDA) Q86HN7 (/IDA) Q9H4B4 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA)
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
8 P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) Q5ABG0 (/IDA) Q5ABG0 (/IDA) Q5ABG0 (/IDA)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
7 P53351 (/ISS) P53351 (/ISS) Q5R4L1 (/ISS) Q5R4L1 (/ISS) Q60806 (/ISS) Q9R011 (/ISS) Q9R012 (/ISS)
Spindle pole GO:0000922
Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
6 P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) Q86HN7 (/IDA)
Centriole GO:0005814
A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
5 Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA) Q9NYY3 (/IDA)
Centriole GO:0005814
A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
5 P53351 (/ISS) P53351 (/ISS) Q5R4L1 (/ISS) Q5R4L1 (/ISS) Q9R012 (/ISS)
Spindle pole body GO:0005816
The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.
5 C8VMZ9 (/IDA) C8VMZ9 (/IDA) Q5ABG0 (/IDA) Q5ABG0 (/IDA) Q5ABG0 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 Q9NYY3 (/TAS) Q9NYY3 (/TAS) Q9NYY3 (/TAS) Q9NYY3 (/TAS) Q9NYY3 (/TAS)
Nuclear chromosome GO:0000228
A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.
3 Q5ABG0 (/IDA) Q5ABG0 (/IDA) Q5ABG0 (/IDA)
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
3 P53351 (/IDA) P53351 (/IDA) Q60806 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P53351 (/ISO) P53351 (/ISO) Q60806 (/ISO)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
3 P53351 (/ISO) P53351 (/ISO) Q60806 (/ISO)
Spindle GO:0005819
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
3 Q5ABG0 (/IDA) Q5ABG0 (/IDA) Q5ABG0 (/IDA)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
3 P53351 (/ISO) P53351 (/ISO) Q60806 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q60806 (/ISS) Q9R011 (/ISS)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
2 Q60806 (/ISS) Q9R011 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q60806 (/ISS) Q9R011 (/ISS)
Golgi stack GO:0005795
The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack.
2 Q60806 (/ISS) Q9R011 (/ISS)
Centriole GO:0005814
A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
2 P53351 (/ISO) P53351 (/ISO)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
2 Q9R011 (/IDA) Q9R012 (/IDA)
Condensed chromosome GO:0000793
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
1 P34331 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q60806 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9N2L7 (/NAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q9H4B4 (/TAS)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 Q9H4B4 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 Q60806 (/ISO)
Golgi stack GO:0005795
The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack.
1 Q9H4B4 (/IDA)
Golgi stack GO:0005795
The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack.
1 Q60806 (/ISO)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 Q9R011 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 Q60806 (/ISO)
Spindle midzone GO:0051233
The area in the center of the spindle where the spindle microtubules from opposite poles overlap.
1 P34331 (/IDA)