The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphorylase Kinase; domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 27: Putative Cyclin-dependent kinase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 35 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
28 P00546 (/IPI) P00546 (/IPI) P00546 (/IPI) P00546 (/IPI) P00546 (/IPI) P00546 (/IPI) P00546 (/IPI) P00546 (/IPI) P00546 (/IPI) P06493 (/IPI)
(18 more)
Cyclin-dependent protein serine/threonine kinase activity GO:0004693
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
24 P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P06493 (/IDA)
(14 more)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
22 P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P06493 (/IDA)
(12 more)
Cyclin-dependent protein serine/threonine kinase activity GO:0004693
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
22 P11440 (/ISS) P13863 (/ISS) P23572 (/ISS) P23572 (/ISS) P23572 (/ISS) P23572 (/ISS) P23572 (/ISS) P24033 (/ISS) P34556 (/ISS) P35567 (/ISS)
(12 more)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
10 P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P23572 (/IDA) P23572 (/IDA) P23572 (/IDA) P23572 (/IDA) P23572 (/IDA)
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
9 P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
9 P00546 (/HDA) P00546 (/HDA) P00546 (/HDA) P00546 (/HDA) P00546 (/HDA) P00546 (/HDA) P00546 (/HDA) P00546 (/HDA) P00546 (/HDA)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
9 P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA)
Cyclin binding GO:0030332
Interacting selectively and non-covalently with cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis.
8 P06493 (/IPI) P06493 (/IPI) P06493 (/IPI) P06493 (/IPI) P06493 (/IPI) P39951 (/IPI) P39951 (/IPI) P39951 (/IPI)
Histone kinase activity GO:0035173
Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes.
8 P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P39951 (/IDA) P39951 (/IDA) P39951 (/IDA)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
6 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P13863 (/TAS)
Cyclin-dependent protein serine/threonine kinase activity GO:0004693
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
6 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) Q00526 (/TAS)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
5 P06493 (/NAS) P06493 (/NAS) P06493 (/NAS) P06493 (/NAS) P06493 (/NAS)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
5 P38973 (/ISM) P38973 (/ISM) P38973 (/ISM) P38973 (/ISM) P38973 (/ISM)
Cyclin-dependent protein serine/threonine kinase activity GO:0004693
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
5 P23572 (/IGI) P23572 (/IGI) P23572 (/IGI) P23572 (/IGI) P23572 (/IGI)
Cyclin-dependent protein serine/threonine kinase activity GO:0004693
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
5 P06493 (/IMP) P06493 (/IMP) P06493 (/IMP) P06493 (/IMP) P06493 (/IMP)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
5 P38973 (/ISM) P38973 (/ISM) P38973 (/ISM) P38973 (/ISM) P38973 (/ISM)
RNA polymerase II CTD heptapeptide repeat kinase activity GO:0008353
Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA polymerase II); phosphorylation occurs on residues in the carboxy-terminal domain (CTD) repeats.
5 P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA)
Cyclin binding GO:0030332
Interacting selectively and non-covalently with cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis.
5 P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA)
Cyclin-dependent protein kinase activity GO:0097472
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
5 P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
4 P11440 (/ISS) P39951 (/ISS) P39951 (/ISS) P39951 (/ISS)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 P11440 (/IDA)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
1 P11440 (/ISO)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
1 P11440 (/ISO)
Cyclin-dependent protein serine/threonine kinase activity GO:0004693
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
1 P11440 (/ISO)
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
1 P34117 (/IPI)
RNA polymerase II CTD heptapeptide repeat kinase activity GO:0008353
Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA polymerase II); phosphorylation occurs on residues in the carboxy-terminal domain (CTD) repeats.
1 P11440 (/ISO)
Kinase activity GO:0016301
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
1 P11440 (/IDA)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
1 P34556 (/IPI)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
1 A8XA58 (/ISS)
Cyclin binding GO:0030332
Interacting selectively and non-covalently with cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis.
1 P11440 (/ISO)
Hsp70 protein binding GO:0030544
Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
1 P11440 (/IPI)
Histone kinase activity GO:0035173
Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes.
1 P11440 (/ISO)
Cyclin-dependent protein kinase activity GO:0097472
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
1 P11440 (/ISO)

There are 173 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
17 P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P11440 (/IDA) P23572 (/IDA) P23572 (/IDA) P23572 (/IDA) P23572 (/IDA)
(7 more)
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
17 P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P06493 (/IDA)
(7 more)
Peptidyl-threonine phosphorylation GO:0018107
The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
14 P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P06493 (/IDA)
(4 more)
Peptidyl-threonine phosphorylation GO:0018107
The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
14 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P06493 (/IMP)
(4 more)
Regulation of circadian rhythm GO:0042752
Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
13 P11440 (/ISS) P13863 (/ISS) P24033 (/ISS) P35567 (/ISS) P35567 (/ISS) P39951 (/ISS) P39951 (/ISS) P39951 (/ISS) P48734 (/ISS) P48734 (/ISS)
(3 more)
Positive regulation of mitotic cell cycle GO:0045931
Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.
13 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P39951 (/IMP)
(3 more)
Golgi disassembly GO:0090166
A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance.
11 P06493 (/ISS) P06493 (/ISS) P06493 (/ISS) P06493 (/ISS) P06493 (/ISS) P11440 (/ISS) P48734 (/ISS) P48734 (/ISS) P48734 (/ISS) P48734 (/ISS)
(1 more)
Positive regulation of meiotic cell cycle GO:0051446
Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle.
10 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P34556 (/IMP)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Meiotic DNA double-strand break processing GO:0000706
The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis.
9 P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI)
DNA double-strand break processing GO:0000729
The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Double-strand break repair via nonhomologous end joining GO:0006303
The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
7-methylguanosine mRNA capping GO:0006370
Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
9 P00546 (/HDA) P00546 (/HDA) P00546 (/HDA) P00546 (/HDA) P00546 (/HDA) P00546 (/HDA) P00546 (/HDA) P00546 (/HDA) P00546 (/HDA)
Post-Golgi vesicle-mediated transport GO:0006892
The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Synaptonemal complex assembly GO:0007130
The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Regulation of budding cell apical bud growth GO:0010568
Any process that modulates the frequency, rate or extent of growth at the tip of a bud, in a cell that reproduces by budding.
9 P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI)
Regulation of budding cell apical bud growth GO:0010568
Any process that modulates the frequency, rate or extent of growth at the tip of a bud, in a cell that reproduces by budding.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Regulation of double-strand break repair via homologous recombination GO:0010569
Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Regulation of filamentous growth GO:0010570
Any process that modulates the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Positive regulation of nuclear cell cycle DNA replication GO:0010571
Any process that activates or increases the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.
9 P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA)
Positive regulation of nuclear cell cycle DNA replication GO:0010571
Any process that activates or increases the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Positive regulation of mitotic spindle pole body separation GO:0010696
Any process that increases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.
9 P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI)
Positive regulation of mitotic spindle pole body separation GO:0010696
Any process that increases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Positive regulation of triglyceride catabolic process GO:0010898
Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.
9 P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI)
Positive regulation of triglyceride catabolic process GO:0010898
Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
9 P11440 (/ISS) P39951 (/ISS) P39951 (/ISS) P39951 (/ISS) P48734 (/ISS) P48734 (/ISS) P48734 (/ISS) P48734 (/ISS) Q5RCH1 (/ISS)
Peptidyl-threonine phosphorylation GO:0018107
The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
9 P11440 (/ISS) P39951 (/ISS) P39951 (/ISS) P39951 (/ISS) P48734 (/ISS) P48734 (/ISS) P48734 (/ISS) P48734 (/ISS) Q5RCH1 (/ISS)
Regulation of telomere maintenance via telomerase GO:0032210
Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase.
9 P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI)
Protein localization to nucleus GO:0034504
A process in which a protein transports or maintains the localization of another protein to the nucleus.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Cellular protein catabolic process GO:0044257
The chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
9 P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI)
Cellular protein catabolic process GO:0044257
The chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Positive regulation of glycogen catabolic process GO:0045819
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Negative regulation of sister chromatid cohesion GO:0045875
Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid cohesion.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
9 P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
9 P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
9 P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI)
Negative regulation of mitotic cell cycle GO:0045930
Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle.
9 P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Positive regulation of meiotic cell cycle GO:0051446
Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle.
9 P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA)
Negative regulation of meiotic cell cycle GO:0051447
Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Regulation of nucleosome density GO:0060303
Any process that modulates the number of nucleosomes in a given region of a chromosome.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Phosphorylation of RNA polymerase II C-terminal domain GO:0070816
The process of introducing a phosphate group on to an amino acid residue in the C-terminal domain of RNA polymerase II. Typically, this occurs during the transcription cycle and results in production of an RNA polymerase II enzyme where the carboxy-terminal domain (CTD) of the largest subunit is extensively phosphorylated, often referred to as hyperphosphorylated or the II(0) form. Specific types of phosphorylation within the CTD are usually associated with specific regions of genes, though there are exceptions. The phosphorylation state regulates the association of specific complexes such as the capping enzyme or 3'-RNA processing machinery to the elongating RNA polymerase complex.
9 P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA)
Regulation of spindle assembly GO:0090169
Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Mitotic spindle assembly GO:0090307
The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of mitosis.
9 P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI)
Positive regulation of trehalose catabolic process GO:1901319
Any process that activates or increases the frequency, rate or extent of trehalose catabolic process.
9 P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI)
Positive regulation of trehalose catabolic process GO:1901319
Any process that activates or increases the frequency, rate or extent of trehalose catabolic process.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Negative regulation of DNA replication origin binding GO:1902596
Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication origin binding.
9 P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI)
Protein localization to spindle microtubule GO:1902889
A process in which a protein is transported to, or maintained in, a location within a spindle microtubule.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Negative regulation of mitotic actomyosin contractile ring assembly GO:1903500
Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring assembly.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Regulation of cellular protein localization GO:1903827
Any process that modulates the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Regulation of protein localization to chromatin GO:1905634
Any process that modulates the frequency, rate or extent of protein localization to chromatin.
9 P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA)
Protein localization to nuclear periphery GO:1990139
A process in which a protein is transported to, or maintained in, a location within the nuclear periphery.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
Mitotic sister chromatid biorientation GO:1990758
The mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed. This is the final step in metaphase plate congression.
9 P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI) P00546 (/IGI)
Negative regulation of double-strand break repair via nonhomologous end joining GO:2001033
Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining.
9 P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP) P00546 (/IMP)
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
7 F1NBD7 (/IMP) P13863 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP)
G1/S transition of mitotic cell cycle GO:0000082
The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
5 P23572 (/IGI) P23572 (/IGI) P23572 (/IGI) P23572 (/IGI) P23572 (/IGI)
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
5 P23572 (/IGI) P23572 (/IGI) P23572 (/IGI) P23572 (/IGI) P23572 (/IGI)
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Activation of MAPK activity GO:0000187
The initiation of the activity of the inactive enzyme MAP kinase (MAPK).
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Microtubule cytoskeleton organization GO:0000226
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
5 P38973 (/TAS) P38973 (/TAS) P38973 (/TAS) P38973 (/TAS) P38973 (/TAS)
Embryonic development via the syncytial blastoderm GO:0001700
The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.
5 P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP)
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Transcription initiation from RNA polymerase II promoter GO:0006367
Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
5 P06493 (/IMP) P06493 (/IMP) P06493 (/IMP) P06493 (/IMP) P06493 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
5 P38973 (/ISM) P38973 (/ISM) P38973 (/ISM) P38973 (/ISM) P38973 (/ISM)
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Mitotic nuclear envelope disassembly GO:0007077
The cell cycle process in which the controlled breakdown of the nuclear envelope during mitotic cell division occurs.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Mitotic G2 DNA damage checkpoint GO:0007095
A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage.
5 P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP)
Centrosome cycle GO:0007098
The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Male meiotic nuclear division GO:0007140
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.
5 P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP)
Spermatogonial cell division GO:0007284
The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes).
5 P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP)
Pronuclear fusion GO:0007344
The merging of two pronuclei in a fertilized egg to fuse and produce a single zygotic genome.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Regulation of G2/M transition of mitotic cell cycle GO:0010389
Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Positive regulation of G2/M transition of mitotic cell cycle GO:0010971
Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
5 P06493 (/IMP) P06493 (/IMP) P06493 (/IMP) P06493 (/IMP) P06493 (/IMP)
Regulation of Schwann cell differentiation GO:0014038
Any process that modulates the frequency, rate or extent of Schwann cell differentiation.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Regulation of DNA-dependent DNA replication initiation GO:0030174
Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.
5 P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP)
Ovarian follicle cell development GO:0030707
The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster.
5 P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP)
Epithelial cell differentiation GO:0030855
The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.
5 P06493 (/IEP) P06493 (/IEP) P06493 (/IEP) P06493 (/IEP) P06493 (/IEP)
Anaphase-promoting complex-dependent catabolic process GO:0031145
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
5 P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP)
Protein localization to kinetochore GO:0034501
Any process in which a protein is transported to, or maintained at, the kinetochore.
5 P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA)
Regulation of circadian rhythm GO:0042752
Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
5 P06493 (/IMP) P06493 (/IMP) P06493 (/IMP) P06493 (/IMP) P06493 (/IMP)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
5 P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA)
Mitotic G2/M transition checkpoint GO:0044818
A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle.
5 P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP)
Regulation of embryonic development GO:0045995
Any process that modulates the frequency, rate or extent of embryonic development.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Germarium-derived cystoblast division GO:0048142
The four rounds of incomplete mitosis undergone by a cystoblast to form a 16-cell cyst of interconnected cells within a germarium. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells. An example of this process is found in Drosophila melanogaster.
5 P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP)
Asymmetric neuroblast division GO:0055059
The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials.
5 P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP)
Ciliary basal body-plasma membrane docking GO:0097711
The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Positive regulation of protein localization to nucleus GO:1900182
Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
5 P06493 (/IMP) P06493 (/IMP) P06493 (/IMP) P06493 (/IMP) P06493 (/IMP)
Regulation of cell cycle phase transition GO:1901987
Any process that modulates the frequency, rate or extent of cell cycle phase transition.
5 P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP) P23572 (/IMP)
Regulation of mitotic cell cycle phase transition GO:1901990
Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Positive regulation of mitochondrial ATP synthesis coupled electron transport GO:1905448
Any process that activates or increases the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.
5 P06493 (/IMP) P06493 (/IMP) P06493 (/IMP) P06493 (/IMP) P06493 (/IMP)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
4 P48734 (/ISS) P48734 (/ISS) P48734 (/ISS) P48734 (/ISS)
G1/S transition of mitotic cell cycle GO:0000082
The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
3 P43063 (/IDA) P43063 (/IDA) P43063 (/IDA)
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
3 P39951 (/IEP) P39951 (/IEP) P39951 (/IEP)
Cell aging GO:0007569
An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469).
3 P39951 (/IDA) P39951 (/IDA) P39951 (/IDA)
Response to toxic substance GO:0009636
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
3 P39951 (/IEP) P39951 (/IEP) P39951 (/IEP)
Response to organonitrogen compound GO:0010243
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
3 P39951 (/IDA) P39951 (/IDA) P39951 (/IDA)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
3 P39951 (/IMP) P39951 (/IMP) P39951 (/IMP)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
3 P39951 (/IEP) P39951 (/IEP) P39951 (/IEP)
Response to amine GO:0014075
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.
3 P39951 (/IEP) P39951 (/IEP) P39951 (/IEP)
Response to activity GO:0014823
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.
3 P39951 (/IEP) P39951 (/IEP) P39951 (/IEP)
Chromosome condensation GO:0030261
The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.
3 P39951 (/IMP) P39951 (/IMP) P39951 (/IMP)
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
3 P43063 (/IMP) P43063 (/IMP) P43063 (/IMP)
Animal organ regeneration GO:0031100
The regrowth of a lost or destroyed animal organ.
3 P39951 (/IMP) P39951 (/IMP) P39951 (/IMP)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
3 P39951 (/IEP) P39951 (/IEP) P39951 (/IEP)
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
3 P39951 (/IEP) P39951 (/IEP) P39951 (/IEP)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
3 P39951 (/IDA) P39951 (/IDA) P39951 (/IDA)
Positive regulation of DNA replication GO:0045740
Any process that activates or increases the frequency, rate or extent of DNA replication.
3 P39951 (/IMP) P39951 (/IMP) P39951 (/IMP)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
3 P39951 (/IEP) P39951 (/IEP) P39951 (/IEP)
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
3 P39951 (/IEP) P39951 (/IEP) P39951 (/IEP)
Response to axon injury GO:0048678
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus.
3 P39951 (/IEP) P39951 (/IEP) P39951 (/IEP)
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
3 P43063 (/IGI) P43063 (/IGI) P43063 (/IGI)
Ventricular cardiac muscle cell development GO:0055015
The process whose specific outcome is the progression of a ventricular cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.
3 P39951 (/IEP) P39951 (/IEP) P39951 (/IEP)
Positive regulation of cardiac muscle cell proliferation GO:0060045
Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation.
3 P39951 (/IMP) P39951 (/IMP) P39951 (/IMP)
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
3 P39951 (/IDA) P39951 (/IDA) P39951 (/IDA)
Cellular response to hydrogen peroxide GO:0070301
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
3 P39951 (/IEP) P39951 (/IEP) P39951 (/IEP)
Golgi disassembly GO:0090166
A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance.
3 P39951 (/IDA) P39951 (/IDA) P39951 (/IDA)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
2 F1NBD7 (/IDA) P13863 (/IDA)
G1/S transition of mitotic cell cycle GO:0000082
The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
1 Q00526 (/TAS)
Meiotic spindle organization GO:0000212
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle.
1 C0SW08 (/IMP)
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
1 P34556 (/IMP)
Double-strand break repair via homologous recombination GO:0000724
The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
1 P13863 (/TAS)
Oocyte maturation GO:0001556
A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.
1 P34556 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 P11440 (/ISO)
Pinocytosis GO:0006907
An endocytosis process that results in the uptake of liquid material by cells from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, called pinosomes, formed by invagination of the plasma membrane.
1 P34117 (/IMP)
Phagocytosis GO:0006909
A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.
1 P34117 (/IMP)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
1 Q00526 (/IDA)
Mitotic G2 DNA damage checkpoint GO:0007095
A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage.
1 P11440 (/IDA)
Cell aging GO:0007569
An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469).
1 P11440 (/ISO)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
1 P11440 (/IDA)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
1 Q00526 (/TAS)
Anterior/posterior axis specification, embryo GO:0008595
The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.
1 P34556 (/IGI)
Regulation of mitotic cell cycle, embryonic GO:0009794
Any process that modulates the frequency, rate or extent of replication and segregation of genetic material in the embryo.
1 Q7T3L7 (/IMP)
Response to organonitrogen compound GO:0010243
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
1 P11440 (/ISO)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 P11440 (/ISO)
Positive regulation of G2/M transition of mitotic cell cycle GO:0010971
Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
1 P11440 (/ISO)
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
1 P11440 (/ISO)
Peptidyl-threonine phosphorylation GO:0018107
The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
1 P11440 (/ISO)
Asexual reproduction GO:0019954
The biological process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process.
1 P34117 (/IMP)
Chromosome condensation GO:0030261
The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.
1 P11440 (/ISO)
Sporulation resulting in formation of a cellular spore GO:0030435
The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
1 P34117 (/IMP)
Animal organ regeneration GO:0031100
The regrowth of a lost or destroyed animal organ.
1 P11440 (/ISO)
Aggregation involved in sorocarp development GO:0031152
The process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.
1 P34117 (/IMP)
Regulation of aggregate size involved in sorocarp development GO:0031157
Any process that modulates the size of the aggregate formed during sorocarp formation.
1 P34117 (/IMP)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436
Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
1 P34556 (/IMP)
Protein localization to kinetochore GO:0034501
Any process in which a protein is transported to, or maintained at, the kinetochore.
1 P11440 (/ISO)
Regulation of circadian rhythm GO:0042752
Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
1 P11440 (/ISO)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 P11440 (/ISO)
Mitotic cell cycle phase transition GO:0044772
The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase.
1 P11440 (/IMP)
G0 to G1 transition GO:0045023
The mitotic cell cycle phase transition whose occurrence commits the cell from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression.
1 Q00526 (/TAS)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
1 P11440 (/ISO)
Positive regulation of DNA replication GO:0045740
Any process that activates or increases the frequency, rate or extent of DNA replication.
1 P11440 (/ISO)
Positive regulation of meiotic nuclear division GO:0045836
Any process that activates or increases the frequency, rate or extent of meiosis.
1 P34556 (/IMP)
Positive regulation of mitotic cell cycle GO:0045931
Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.
1 P11440 (/ISO)
Cell division GO:0051301
The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
1 P34556 (/IMP)
Cell division GO:0051301
The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
1 A8XA58 (/ISS)
Meiotic cell cycle GO:0051321
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
1 P34556 (/IMP)
Positive regulation of meiotic cell cycle GO:0051446
Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle.
1 A8XA58 (/ISS)
Positive regulation of cardiac muscle cell proliferation GO:0060045
Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation.
1 P11440 (/ISO)
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
1 P11440 (/ISO)
Positive regulation of protein serine/threonine kinase activity GO:0071902
Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity.
1 P34556 (/IMP)
Golgi disassembly GO:0090166
A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance.
1 P11440 (/ISO)
Positive regulation of protein localization to nucleus GO:1900182
Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
1 P11440 (/ISO)
Meiotic cell cycle process involved in oocyte maturation GO:1903537
Any meiotic cell cycle process that is involved in oocyte maturation.
1 C0SW08 (/IMP)
Positive regulation of meiotic cell cycle process involved in oocyte maturation GO:1904146
Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.
1 C0SW08 (/IMP)
Positive regulation of mitochondrial ATP synthesis coupled electron transport GO:1905448
Any process that activates or increases the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.
1 P11440 (/ISO)

There are 40 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
25 A0A024QZJ8 (/IDA) A0A024QZJ8 (/IDA) A0A024QZJ8 (/IDA) A0A024QZJ8 (/IDA) A0A024QZP7 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA)
(15 more)
Cyclin-dependent protein kinase holoenzyme complex GO:0000307
Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner.
14 P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P06493 (/IDA)
(4 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
14 P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P34117 (/IDA)
(4 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
10 A0A024QZJ8 (/IDA) A0A024QZJ8 (/IDA) A0A024QZJ8 (/IDA) A0A024QZJ8 (/IDA) A0A024QZP7 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
9 P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
9 P11440 (/ISS) P39951 (/ISS) P39951 (/ISS) P39951 (/ISS) P48734 (/ISS) P48734 (/ISS) P48734 (/ISS) P48734 (/ISS) Q5RCH1 (/ISS)
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
9 P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
9 P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA) P00546 (/IDA)
Mitotic spindle GO:0072686
A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
9 P11440 (/ISS) P39951 (/ISS) P39951 (/ISS) P39951 (/ISS) P48734 (/ISS) P48734 (/ISS) P48734 (/ISS) P48734 (/ISS) Q5RCH1 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
8 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P24033 (/TAS) P35567 (/TAS) P35567 (/TAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
7 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P11440 (/TAS) P13863 (/TAS)
Nuclear chromosome, telomeric region GO:0000784
The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and associated proteins.
5 P06493 (/HDA) P06493 (/HDA) P06493 (/HDA) P06493 (/HDA) P06493 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
5 P38973 (/IDA) P38973 (/IDA) P38973 (/IDA) P38973 (/IDA) P38973 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
5 P38973 (/IDA) P38973 (/IDA) P38973 (/IDA) P38973 (/IDA) P38973 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
5 P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS) P06493 (/TAS)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
5 P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA)
Spindle microtubule GO:0005876
Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.
5 P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
5 P06493 (/HDA) P06493 (/HDA) P06493 (/HDA) P06493 (/HDA) P06493 (/HDA)
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
5 P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
5 P06493 (/HDA) P06493 (/HDA) P06493 (/HDA) P06493 (/HDA) P06493 (/HDA)
Mitotic spindle GO:0072686
A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
5 P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA) P06493 (/IDA)
Cyclin B1-CDK1 complex GO:0097125
A protein complex consisting of cyclin B1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
5 P06493 (/IMP) P06493 (/IMP) P06493 (/IMP) P06493 (/IMP) P06493 (/IMP)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 P48734 (/ISS) P48734 (/ISS) P48734 (/ISS) P48734 (/ISS)
Spindle microtubule GO:0005876
Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.
4 P48734 (/ISS) P48734 (/ISS) P48734 (/ISS) P48734 (/ISS)
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
4 P48734 (/ISS) P48734 (/ISS) P48734 (/ISS) P48734 (/ISS)
Cyclin-dependent protein kinase holoenzyme complex GO:0000307
Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner.
1 P11440 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P11440 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 P34117 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P11440 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q4QC88 (/ISO)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
1 P11440 (/ISO)
Spindle pole body GO:0005816
The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.
1 Q00646 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P11440 (/ISO)
Spindle microtubule GO:0005876
Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.
1 P11440 (/ISO)
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
1 P11440 (/ISO)
Germinal vesicle GO:0042585
The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity.
1 C0SW08 (/IDA)
Endoplasmic reticulum exit site GO:0070971
An endoplasmic reticulum part at which COPII-coated vesicles are produced.
1 C0SW08 (/IDA)
Mitotic spindle GO:0072686
A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
1 P11440 (/ISO)
Cyclin B1-CDK1 complex GO:0097125
A protein complex consisting of cyclin B1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
1 P11440 (/ISO)
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