The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphorylase Kinase; domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 263: Choline kinase alpha

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 17 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Choline kinase activity GO:0004103
Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H(+).
9 B3GWD5 (/IDA) O17610 (/IDA) O54783 (/IDA) O54804 (/IDA) P35790 (/IDA) Q01134 (/IDA) Q22942 (/IDA) Q9Y259 (/IDA) Q9Y259 (/IDA)
Choline kinase activity GO:0004103
Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H(+).
5 O54783 (/ISS) O54804 (/ISS) O55229 (/ISS) O55229 (/ISS) Q01134 (/ISS)
Ethanolamine kinase activity GO:0004305
Catalysis of the reaction: ATP + ethanolamine = ADP + 2 H(+) + phosphoethanolamine.
4 P35790 (/IDA) Q01134 (/IDA) Q9Y259 (/IDA) Q9Y259 (/IDA)
Choline kinase activity GO:0004103
Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H(+).
3 O54804 (/ISO) O55229 (/ISO) O55229 (/ISO)
Ethanolamine kinase activity GO:0004305
Catalysis of the reaction: ATP + ethanolamine = ADP + 2 H(+) + phosphoethanolamine.
3 O54804 (/ISO) O55229 (/ISO) O55229 (/ISO)
Choline kinase activity GO:0004103
Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H(+).
2 O55229 (/IMP) O55229 (/IMP)
Choline kinase activity GO:0004103
Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H(+).
2 P35790 (/TAS) Q01134 (/TAS)
Ethanolamine kinase activity GO:0004305
Catalysis of the reaction: ATP + ethanolamine = ADP + 2 H(+) + phosphoethanolamine.
2 O54804 (/ISS) Q01134 (/ISS)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
2 O54804 (/ISS) Q01134 (/ISS)
Cholinesterase activity GO:0004104
Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion.
1 O54804 (/IDA)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q01134 (/IDA)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 O54804 (/ISO)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
1 P35790 (/IDA)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
1 O54804 (/ISO)
Choline binding GO:0033265
Interacting selectively and non-covalently with choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium.
1 Q01134 (/IDA)
Choline binding GO:0033265
Interacting selectively and non-covalently with choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium.
1 O54804 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 O54804 (/IPI)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphatidylethanolamine biosynthetic process GO:0006646
The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
5 O54783 (/ISS) O54804 (/ISS) O55229 (/ISS) O55229 (/ISS) Q01134 (/ISS)
Phosphatidylethanolamine biosynthetic process GO:0006646
The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
3 P35790 (/IDA) Q9Y259 (/IDA) Q9Y259 (/IDA)
Phosphatidylethanolamine biosynthetic process GO:0006646
The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
3 O54804 (/ISO) O55229 (/ISO) O55229 (/ISO)
Phosphatidylethanolamine biosynthetic process GO:0006646
The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
3 P35790 (/TAS) Q9Y259 (/TAS) Q9Y259 (/TAS)
Phosphatidylcholine biosynthetic process GO:0006656
The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
3 P35790 (/TAS) Q9Y259 (/TAS) Q9Y259 (/TAS)
CDP-choline pathway GO:0006657
The phosphatidylcholine biosynthetic process that begins with the phosphorylation of choline and ends with the combination of CDP-choline with diacylglycerol to form phosphatidylcholine.
3 B3GWD5 (/IDA) O17610 (/IDA) Q22942 (/IDA)
Phosphatidylcholine biosynthetic process GO:0006656
The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
2 O54804 (/IDA) P35790 (/IDA)
Phosphatidylcholine biosynthetic process GO:0006656
The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
2 O55229 (/IMP) O55229 (/IMP)
Phosphatidylcholine biosynthetic process GO:0006656
The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
2 O54804 (/ISS) Q01134 (/ISS)
Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
2 O55229 (/IMP) O55229 (/IMP)
Ethanolamine metabolic process GO:0006580
The chemical reactions and pathways involving ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).
1 Q01134 (/IDA)
Ethanolamine metabolic process GO:0006580
The chemical reactions and pathways involving ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).
1 O54804 (/ISO)
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
1 P35790 (/TAS)
Phosphatidylcholine biosynthetic process GO:0006656
The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
1 O54804 (/ISO)
Lipid transport GO:0006869
The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
1 P35790 (/TAS)
Response to toxic substance GO:0009636
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
1 Q01134 (/IEP)
Choline metabolic process GO:0019695
The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
1 Q01134 (/IDA)
Choline metabolic process GO:0019695
The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
1 O54804 (/ISO)
Response to 3-methylcholanthrene GO:1904681
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus.
1 Q01134 (/IEP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 P35790 (/TAS) Q9Y259 (/TAS) Q9Y259 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 B3GWD5 (/IDA) O17610 (/IDA)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
2 B3GWD5 (/IDA) O17610 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...