The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"ligand-binding face of the semaphorins, domain 2
".
FunFam 40: Integrin beta
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
2 | Q27591 (/IPI) Q27591 (/IPI) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phagocytosis GO:0006909
A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.
|
2 | Q27591 (/IMP) Q27591 (/IMP) |
|
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
|
2 | Q27591 (/TAS) Q27591 (/TAS) |
|
Cell-matrix adhesion GO:0007160
The binding of a cell to the extracellular matrix via adhesion molecules.
|
2 | Q27591 (/TAS) Q27591 (/TAS) |
|
Cell adhesion mediated by integrin GO:0033627
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.
|
2 | Q27591 (/ISS) Q27591 (/ISS) |
|
Melanotic encapsulation of foreign target GO:0035011
Formation of a multilayered, melanized sheath of cells around a foreign invader.
|
2 | Q27591 (/IMP) Q27591 (/IMP) |
|
Apoptotic cell clearance GO:0043277
The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.
|
2 | Q27591 (/IMP) Q27591 (/IMP) |
|
Negative regulation of synaptic growth at neuromuscular junction GO:0045886
Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic growth at neuromuscular junction.
|
2 | Q27591 (/IMP) Q27591 (/IMP) |
|
Muscle cell cellular homeostasis GO:0046716
The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.
|
2 | Q27591 (/IGI) Q27591 (/IGI) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integrin complex GO:0008305
A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands.
|
2 | Q27591 (/IDA) Q27591 (/IDA) |
|
Integrin complex GO:0008305
A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands.
|
2 | Q27591 (/ISS) Q27591 (/ISS) |
|
Integrin complex GO:0008305
A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands.
|
2 | Q27591 (/NAS) Q27591 (/NAS) |
|
Integrin complex GO:0008305
A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands.
|
2 | Q27591 (/TAS) Q27591 (/TAS) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q27591 (/IDA) Q27591 (/IDA) |
