The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
mini-chromosome maintenance (MCM) complex, chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: DNA helicase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 P34647 (/IPI) P97311 (/IPI) P97311 (/IPI) Q14566 (/IPI) Q14566 (/IPI) Q14566 (/IPI) Q9V461 (/IPI) Q9V461 (/IPI)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
3 Q14566 (/NAS) Q14566 (/NAS) Q14566 (/NAS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
3 Q14566 (/IPI) Q14566 (/IPI) Q14566 (/IPI)
Single-stranded DNA binding GO:0003697
Interacting selectively and non-covalently with single-stranded DNA.
2 P97311 (/IPI) P97311 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 P97311 (/ISO) P97311 (/ISO)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
5 Q14566 (/TAS) Q14566 (/TAS) Q14566 (/TAS) Q9V461 (/TAS) Q9V461 (/TAS)
G1/S transition of mitotic cell cycle GO:0000082
The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
3 Q14566 (/TAS) Q14566 (/TAS) Q14566 (/TAS)
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
3 Q14566 (/NAS) Q14566 (/NAS) Q14566 (/NAS)
Regulation of DNA-dependent DNA replication initiation GO:0030174
Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.
3 Q498J7 (/IC) Q7ZY18 (/IC) Q7ZY18 (/IC)
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
2 Q9V461 (/IMP) Q9V461 (/IMP)
DNA unwinding involved in DNA replication GO:0006268
The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.
2 Q5FWY4 (/IDA) Q5FWY4 (/IDA)
DNA unwinding involved in DNA replication GO:0006268
The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.
2 P97311 (/IPI) P97311 (/IPI)
Eggshell chorion gene amplification GO:0007307
Amplification by up to 60-fold of the loci containing the chorion gene clusters. Amplification is necessary for the rapid synthesis of chorion proteins by the follicle cells, and occurs by repeated firing of one or more origins located within each gene cluster.
2 Q9V461 (/IMP) Q9V461 (/IMP)
Eggshell chorion gene amplification GO:0007307
Amplification by up to 60-fold of the loci containing the chorion gene clusters. Amplification is necessary for the rapid synthesis of chorion proteins by the follicle cells, and occurs by repeated firing of one or more origins located within each gene cluster.
2 Q9V461 (/TAS) Q9V461 (/TAS)
Regulation of DNA-dependent DNA replication initiation GO:0030174
Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.
2 Q5FWY4 (/IDA) Q5FWY4 (/IDA)
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
1 Q29JI9 (/ISS)
DNA unwinding involved in DNA replication GO:0006268
The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.
1 Q28CM3 (/ISS)
Regulation of DNA-dependent DNA replication initiation GO:0030174
Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.
1 Q28CM3 (/ISS)

There are 14 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 P97311 (/IDA) P97311 (/IDA) Q14566 (/IDA) Q14566 (/IDA) Q14566 (/IDA) Q9V461 (/IDA) Q9V461 (/IDA)
MCM complex GO:0042555
A hexameric protein complex required for the initiation and regulation of DNA replication.
5 Q14566 (/IDA) Q14566 (/IDA) Q14566 (/IDA) Q5FWY4 (/IDA) Q5FWY4 (/IDA)
MCM complex GO:0042555
A hexameric protein complex required for the initiation and regulation of DNA replication.
5 P97311 (/ISS) P97311 (/ISS) Q28CM3 (/ISS) Q2KIZ8 (/ISS) Q6P1V8 (/ISS)
Nuclear chromosome, telomeric region GO:0000784
The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and associated proteins.
3 Q14566 (/HDA) Q14566 (/HDA) Q14566 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q14566 (/NAS) Q14566 (/NAS) Q14566 (/NAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 Q14566 (/IDA) Q14566 (/IDA) Q14566 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 Q14566 (/TAS) Q14566 (/TAS) Q14566 (/TAS)
MCM complex GO:0042555
A hexameric protein complex required for the initiation and regulation of DNA replication.
3 Q498J7 (/IPI) Q7ZY18 (/IPI) Q7ZY18 (/IPI)
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
2 Q5FWY4 (/IDA) Q5FWY4 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P97311 (/ISO) P97311 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 P97311 (/ISO) P97311 (/ISO)
MCM complex GO:0042555
A hexameric protein complex required for the initiation and regulation of DNA replication.
2 P97311 (/ISO) P97311 (/ISO)
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
1 Q28CM3 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q29JI9 (/ISS)