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CATH Superfamily 3.30.1520.10

Phox-like domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phox-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Sorting nexin 12Putative sorting nexin-16Sorting nexin 10Sorting nexin 1Non-specific serine/threonine protein kinasePutative sorting nexin-19Sorting nexin-3, variantsorting nexin-24Vacuolar morphogenesis proteinSC:2Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alphasorting nexin-14 isoform X1Sorting nexin-17 isoform1Kinesin family member 16BNeutrophil cytosol factor 1Bud emergence proteinSC:3nischarin isoform X1Neutrophil cytosol factor 4Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gammaNADPH oxidase organizer 1Sorting nexinsorting nexin-27 isoform X2Sorting nexinSH3 and PX domain-containing protein 2Brho GTPase-activating protein 32 isoform X2PX domain-containing protein kinase-like protein isoform X6Putative Sorting nexin 3Sorting nexin 13Sorting nexin 2ribosomal protein S6 kinase delta-1 isoform X1PhospholipaseSorting nexin 20Phospholipasesorting nexin 1 isoform X2sorting nexin-15 isoform X1Sorting nexin 4Sorting nexin 8Sorting nexin 25Vacuolar protein sorting-associated protein 17Sorting nexin-4 proteinHCLS1 binding protein 3Sorting nexin mvp-1PX domain containing serine/threonine kinase likeProtein kinase activator Bem1Sorting nexin mvp1SH3 and PX domain-containing protein 2BKinesin-like protein KIF16BZinc finger CCHC domain-containing protein 2sorting nexin-17 isoform X4Sorting nexinsorting nexin-16 isoform X2Vacuolar sorting protein VPS1Related to Protein scd2/ral3PhospholipasePutative SNARE complex subunit (Vam7)Uncharacterized proteinNon-specific serine/threonine protein kinasePhospholipasePhosphoinositide-binding protein, putativeSnx4pVPS9 domain protein, putativeSorting nexin 2BPhox (PX) domain-containing proteinSorting nexin 1Unplaced genomic scaffold supercont1.141, whole genome shotgun sequenceBlast:Sorting nexin-16PX domain protein (AFU_orthologue AFUA_2G07450)Related to BEM3-GTPase-activating proteinUnplaced genomic scaffold supercont1.259, whole genome shotgun sequenceAtg20pYPT35p Endosomal proteinYPR097W-like proteinPhox domain-containing proteinYKR078W-like proteinSorting nexinMdm1pSorting nexin 20Phosphoinositide-binding protein, putativeSorting nexin-17 homologPX domain protein (AFU_orthologue AFUA_3G08020)Conserved fungal proteinSorting NeXinNon-specific serine/threonine protein kinaseGG16618Serine/threonine protein kinase, putativeLiver stage antigen-like protein/ PX domainSorting nexin-4GD16870Atypical/BCR protein kinaseneutrophil cytosolic factor 1 isoform X1PX domain-containing proteinUnplaced genomic scaffold supercont1.4, whole genome shotgun sequenceSorting nexin-2Vacuolar protein sorting-associated protein vps17Kinesin family member 16BRho GTPase-activating protein 33PX domain containing proteinPX domain containing protein, putativeRho GTPase-activating protein 33Differentiation inhibitory kinaseUncharacterized protein, isoform BUncharacterized proteinSNX6 isoform 6Predicted proteinUncharacterized proteinYALI0B01056pVacuolar protein sorting-associated protein 17Phosphoinositide-binding protein, putativeSorting nexin 7Vacuolar protein sorting-associated protein 17PhospholipaseUncharacterized proteinUncharacterized proteinRho GTPase-activating protein (RhoGAP), putativeBud emergence protein, putativeRibosomal protein S6 kinase C1Uncharacterized proteinUncharacterized proteinSorting nexinProbable serine/threonine-protein kinase DDB_G0272282Uncharacterized proteinUncharacterized proteinUncharacterized proteinPhosphatidylinositol 3-kinase piki-1Uncharacterized proteinAER438CpRho GTPase activator (Bem3), putative (AFU_orthologue AFUA_6G06400)YALI0C16412pUncharacterized proteinUncharacterized proteinYALI0E07601pUncharacterized proteinUncharacterized proteinUPF0507 protein YALI0E18612gPhospholipasePutative nischarin modulator of integrin alpha5 subunit actionChromosome 19, whole genome shotgun sequenceUncharacterized proteinNeutrophil cytosol factor 4Predicted proteinUncharacterized proteinPredicted proteinPX domain-containing protein C1450.12Uncharacterized proteinSorting nexin C1711.11Autophagy-related protein 20Uncharacterized proteinSorting nexin mvp1Uncharacterized proteinUncharacterized proteinSorting nexin 3Predicted proteinUncharacterized proteinSorting nexin-41Sorting nexin 1Protein CBG07900Sorting nexin 6Sorting nexin-4Uncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinSorting nexin-12Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinNon-specific serine/threonine protein kinaseVacuolar morphogenesis protein 7 homologUncharacterized proteinNon-specific serine/threonine protein kinasePredicted proteinGTPase-activating protein BEM3Protein CBR-SNX-6Uncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinPhospholipaseNon-specific serine/threonine protein kinasePredicted proteinUncharacterized proteinRibosomal protein S6 kinase C1Predicted proteinPredicted proteinNischarin-like ProteinPhospholipaseUncharacterized proteinUncharacterized proteinUncharacterized proteinPhopholipase D, putativeUncharacterized proteinNeutrophil cytosolic factor 4SH3 and PX domains 2BUncharacterized proteinUncharacterized protein
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FunFam 28: sorting nexin 1 isoform X2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 2 Q9FG38 (/IPI) Q9FG38 (/IPI)
Showing 1 to 1 of 1 entries

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein targeting to vacuole GO:0006623
The process of directing proteins towards the vacuole, usually using signals contained within the protein.
 2 Q9FG38 (/IMP) Q9FG38 (/IMP)
Golgi to vacuole transport GO:0006896
The directed movement of substances from the Golgi to the vacuole.
 2 Q9FG38 (/IDA) Q9FG38 (/IDA)
Endosome to lysosome transport GO:0008333
The directed movement of substances from endosomes to lysosomes.
 2 Q9FG38 (/TAS) Q9FG38 (/TAS)
Positive gravitropism GO:0009958
The orientation of plant parts towards gravity.
 2 Q9FG38 (/IMP) Q9FG38 (/IMP)
Auxin homeostasis GO:0010252
A homeostatic process that maintains an endogenous steady-state concentration of primary auxin, or constant level of auxin in a biological system, by a number of biochemical processes including transport, biosynthesis, catabolism and conjugation.
 2 Q9FG38 (/IDA) Q9FG38 (/IDA)
Root development GO:0048364
The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.
 2 Q9FG38 (/IMP) Q9FG38 (/IMP)
Showing 1 to 6 of 6 entries

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
 2 Q9FG38 (/IDA) Q9FG38 (/IDA)
Multivesicular body GO:0005771
A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
 2 Q9FG38 (/IDA) Q9FG38 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 2 Q9FG38 (/IDA) Q9FG38 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 2 Q9FG38 (/IDA) Q9FG38 (/IDA)
Retromer complex GO:0030904
A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35.
 2 Q9FG38 (/IDA) Q9FG38 (/IDA)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
 2 Q9FG38 (/IDA) Q9FG38 (/IDA)
Showing 1 to 6 of 6 entries
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