The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
ATP-grasp fold, A domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 12: Biotin carboxylase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Biotin carboxylase activity GO:0004075
Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein.
117 P24182 (/IDA) P24182 (/IDA) P24182 (/IDA) P24182 (/IDA) P24182 (/IDA) P24182 (/IDA) P24182 (/IDA) P24182 (/IDA) P24182 (/IDA) P24182 (/IDA)
(107 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
117 P24182 (/IPI) P24182 (/IPI) P24182 (/IPI) P24182 (/IPI) P24182 (/IPI) P24182 (/IPI) P24182 (/IPI) P24182 (/IPI) P24182 (/IPI) P24182 (/IPI)
(107 more)
Biotin carboxylase activity GO:0004075
Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein.
9 Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
117 P24182 (/IGI) P24182 (/IGI) P24182 (/IGI) P24182 (/IGI) P24182 (/IGI) P24182 (/IGI) P24182 (/IGI) P24182 (/IGI) P24182 (/IGI) P24182 (/IGI)
(107 more)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
117 P24182 (/IMP) P24182 (/IMP) P24182 (/IMP) P24182 (/IMP) P24182 (/IMP) P24182 (/IMP) P24182 (/IMP) P24182 (/IMP) P24182 (/IMP) P24182 (/IMP)
(107 more)
Negative regulation of fatty acid biosynthetic process GO:0045717
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
117 P24182 (/IMP) P24182 (/IMP) P24182 (/IMP) P24182 (/IMP) P24182 (/IMP) P24182 (/IMP) P24182 (/IMP) P24182 (/IMP) P24182 (/IMP) P24182 (/IMP)
(107 more)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
9 Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
117 P24182 (/IC) P24182 (/IC) P24182 (/IC) P24182 (/IC) P24182 (/IC) P24182 (/IC) P24182 (/IC) P24182 (/IC) P24182 (/IC) P24182 (/IC)
(107 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
117 P24182 (/IDA) P24182 (/IDA) P24182 (/IDA) P24182 (/IDA) P24182 (/IDA) P24182 (/IDA) P24182 (/IDA) P24182 (/IDA) P24182 (/IDA) P24182 (/IDA)
(107 more)
Acetyl-CoA carboxylase complex GO:0009317
A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex.
9 Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS) Q9KV62 (/ISS)
CATH-Gene3D is a Global Biodata Core Resource Learn more...