The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Muscleblind-like 1 isoform 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulatory region RNA binding GO:0001069
Interacting selectively and non-covalently with a RNA region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.
31 A0A0G2JX72 (/IDA) F1M9N4 (/IDA) F1M9N4 (/IDA) F1M9N4 (/IDA) F1M9N4 (/IDA) F1M9N4 (/IDA) F1M9N4 (/IDA) F1M9N4 (/IDA) F1M9N4 (/IDA) F1M9N4 (/IDA)
(21 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
21 Q5VZF2 (/HDA) Q5VZF2 (/HDA) Q5VZF2 (/HDA) Q5VZF2 (/HDA) Q5VZF2 (/HDA) Q5VZF2 (/HDA) Q5VZF2 (/HDA) Q5VZF2 (/HDA) Q5VZF2 (/HDA) Q5VZF2 (/HDA)
(11 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 Q86VM6 (/IPI) Q86VM6 (/IPI) Q86VM6 (/IPI) Q86VM6 (/IPI) Q9NR56 (/IPI) Q9NR56 (/IPI) Q9NR56 (/IPI) Q9NR56 (/IPI) Q9NUK0 (/IPI)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
4 Q9NR56 (/IDA) Q9NR56 (/IDA) Q9NR56 (/IDA) Q9NR56 (/IDA)
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
4 Q9NR56 (/IDA) Q9NR56 (/IDA) Q9NR56 (/IDA) Q9NR56 (/IDA)
Regulatory region RNA binding GO:0001069
Interacting selectively and non-covalently with a RNA region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.
1 Q9JKP5 (/ISO)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q9JKP5 (/ISO)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q9JKP5 (/ISS)
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
1 Q9JKP5 (/ISO)
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
1 Q9JKP5 (/ISS)

There are 26 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of RNA splicing GO:0043484
Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
21 Q5VZF2 (/IDA) Q5VZF2 (/IDA) Q5VZF2 (/IDA) Q5VZF2 (/IDA) Q5VZF2 (/IDA) Q5VZF2 (/IDA) Q5VZF2 (/IDA) Q5VZF2 (/IDA) Q5VZF2 (/IDA) Q5VZF2 (/IDA)
(11 more)
Regulation of RNA splicing GO:0043484
Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
21 Q5R4F5 (/ISS) Q5R4F5 (/ISS) Q5R4F5 (/ISS) Q5R4F5 (/ISS) Q5R4F5 (/ISS) Q5R4F5 (/ISS) Q5R4F5 (/ISS) Q5R4F5 (/ISS) Q5R4F5 (/ISS) Q5R4F5 (/ISS)
(11 more)
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
9 A0A2R8QF26 (/IMP) A5YC69 (/IMP) A5YC70 (/IMP) A5YC71 (/IMP) A9UH07 (/IMP) B7ZUV4 (/IMP) B8JIV1 (/IMP) F1Q5U6 (/IMP) F1RE65 (/IMP)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
9 A0A2R8QF26 (/IMP) A5YC69 (/IMP) A5YC70 (/IMP) A5YC71 (/IMP) A9UH07 (/IMP) B7ZUV4 (/IMP) B8JIV1 (/IMP) F1Q5U6 (/IMP) F1RE65 (/IMP)
Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
9 A0A2R8QF26 (/IMP) A5YC69 (/IMP) A5YC70 (/IMP) A5YC71 (/IMP) A9UH07 (/IMP) B7ZUV4 (/IMP) B8JIV1 (/IMP) F1Q5U6 (/IMP) F1RE65 (/IMP)
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
9 A0A2R8QF26 (/IMP) A5YC69 (/IMP) A5YC70 (/IMP) A5YC71 (/IMP) A9UH07 (/IMP) B7ZUV4 (/IMP) B8JIV1 (/IMP) F1Q5U6 (/IMP) F1RE65 (/IMP)
Muscle fiber development GO:0048747
The process whose specific outcome is the progression of the muscle fiber over time, from its formation to the mature structure. In skeletal muscle, fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
9 A0A2R8QF26 (/IMP) A5YC69 (/IMP) A5YC70 (/IMP) A5YC71 (/IMP) A9UH07 (/IMP) B7ZUV4 (/IMP) B8JIV1 (/IMP) F1Q5U6 (/IMP) F1RE65 (/IMP)
Regulation of RNA splicing GO:0043484
Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
5 Q8C181 (/ISO) Q8C181 (/ISO) Q8R003 (/ISO) Q8R003 (/ISO) Q9JKP5 (/ISO)
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
4 Q9NR56 (/ISS) Q9NR56 (/ISS) Q9NR56 (/ISS) Q9NR56 (/ISS)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
4 Q9NR56 (/ISS) Q9NR56 (/ISS) Q9NR56 (/ISS) Q9NR56 (/ISS)
RNA splicing GO:0008380
The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
4 Q9NR56 (/IDA) Q9NR56 (/IDA) Q9NR56 (/IDA) Q9NR56 (/IDA)
Embryonic limb morphogenesis GO:0030326
The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.
4 Q9NR56 (/ISS) Q9NR56 (/ISS) Q9NR56 (/ISS) Q9NR56 (/ISS)
Myoblast differentiation GO:0045445
The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.
4 Q9NR56 (/ISS) Q9NR56 (/ISS) Q9NR56 (/ISS) Q9NR56 (/ISS)
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
2 Q8C181 (/IMP) Q8C181 (/IMP)
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
2 Q8C181 (/ISO) Q8C181 (/ISO)
Negative regulation of myoblast differentiation GO:0045662
Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
2 Q8R003 (/IDA) Q8R003 (/IDA)
Alternative mRNA splicing, via spliceosome GO:0000380
The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.
1 Q9JKP5 (/IMP)
Alternative mRNA splicing, via spliceosome GO:0000380
The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.
1 Q9JKP5 (/ISO)
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
1 Q9JKP5 (/IEP)
MRNA splice site selection GO:0006376
Selection of a splice site by components of the assembling spliceosome.
1 Q9JKP5 (/IMP)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
1 Q9JKP5 (/IEP)
Skeletal muscle tissue development GO:0007519
The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.
1 Q9JKP5 (/IMP)
RNA splicing GO:0008380
The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
1 Q9JKP5 (/ISO)
RNA splicing GO:0008380
The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
1 Q9JKP5 (/ISS)
Embryonic limb morphogenesis GO:0030326
The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.
1 Q9JKP5 (/IEP)
Myoblast differentiation GO:0045445
The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.
1 Q9JKP5 (/IDA)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
47 A0A0A0MQX8 (/IDA) A0A0A0MQX8 (/IDA) A0A0A0MQX8 (/IDA) A0A0A0MQX8 (/IDA) A2A3S3 (/IDA) A2A3S3 (/IDA) A2A3S3 (/IDA) A2A3S3 (/IDA) A2A3S3 (/IDA) A2A3S3 (/IDA)
(37 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
36 A0A0G2JX72 (/IDA) F1M9N4 (/IDA) F1M9N4 (/IDA) F1M9N4 (/IDA) F1M9N4 (/IDA) F1M9N4 (/IDA) F1M9N4 (/IDA) F1M9N4 (/IDA) F1M9N4 (/IDA) F1M9N4 (/IDA)
(26 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
21 A0A0A0MQX8 (/IDA) A0A0A0MQX8 (/IDA) A0A0A0MQX8 (/IDA) A0A0A0MQX8 (/IDA) C9JCX1 (/IDA) C9JCX1 (/IDA) C9JP00 (/IDA) C9JP00 (/IDA) C9JP00 (/IDA) C9JP00 (/IDA)
(11 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 Q9JKP5 (/IDA) Q9NR56 (/IDA) Q9NR56 (/IDA) Q9NR56 (/IDA) Q9NR56 (/IDA)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
4 Q9NR56 (/IDA) Q9NR56 (/IDA) Q9NR56 (/IDA) Q9NR56 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 Q8C181 (/ISO) Q8C181 (/ISO) Q9JKP5 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9JKP5 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9JKP5 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9JKP5 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9JKP5 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9JKP5 (/ISO)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
1 Q9JKP5 (/ISO)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
1 Q9JKP5 (/ISS)
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