The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
K Homology domain, type 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Polyribonucleotide nucleotidyltransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
31 P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI)
(21 more)
Polyribonucleotide nucleotidyltransferase activity GO:0004654
Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
28 Q2GGA4 (/ISS) Q2GJV5 (/ISS) Q2GJV5 (/ISS) Q2GJV5 (/ISS) Q2GJV5 (/ISS) Q3Z7V6 (/ISS) Q5HTK8 (/ISS) Q5HTK8 (/ISS) Q5LN23 (/ISS) Q609C6 (/ISS)
(18 more)
3'-5'-exoribonuclease activity GO:0000175
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
20 P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA)
(10 more)
Polyribonucleotide nucleotidyltransferase activity GO:0004654
Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
20 P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA)
(10 more)
Cyclic-di-GMP binding GO:0035438
Interacting selectively and non-covalently with cyclic-di-GMP, cyclic dimeric guanosine monophosphate.
20 P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA)
(10 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
20 P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI)
(10 more)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
11 Q2GGA4 (/ISS) Q2GJV5 (/ISS) Q2GJV5 (/ISS) Q2GJV5 (/ISS) Q2GJV5 (/ISS) Q3Z7V6 (/ISS) Q74CS9 (/ISS) Q81WM8 (/ISS) Q81WM8 (/ISS) Q81WM8 (/ISS)
(1 more)
3'-5'-exoribonuclease activity GO:0000175
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
2 Q8GZQ3 (/IMP) Q9S7G6 (/IMP)
Polyribonucleotide nucleotidyltransferase activity GO:0004654
Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
2 Q8GZQ3 (/IMP) Q9S7G6 (/IMP)
3'-5'-exoribonuclease activity GO:0000175
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
1 Q5LN23 (/ISS)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
20 P05055 (/IMP) P05055 (/IMP) P05055 (/IMP) P05055 (/IMP) P05055 (/IMP) P05055 (/IMP) P05055 (/IMP) P05055 (/IMP) P05055 (/IMP) P05055 (/IMP)
(10 more)
MRNA catabolic process GO:0006402
The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
18 Q2GGA4 (/ISS) Q2GJV5 (/ISS) Q2GJV5 (/ISS) Q2GJV5 (/ISS) Q2GJV5 (/ISS) Q3Z7V6 (/ISS) Q5HTK8 (/ISS) Q5HTK8 (/ISS) Q5LN23 (/ISS) Q71ZZ1 (/ISS)
(8 more)
RNA catabolic process GO:0006401
The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
10 Q609C6 (/ISS) Q83D87 (/ISS) Q83D87 (/ISS) Q83D87 (/ISS) Q9KU76 (/ISS) Q9KU76 (/ISS) Q9KU76 (/ISS) Q9KU76 (/ISS) Q9KU76 (/ISS) Q9KU76 (/ISS)
Regulation of mitochondrial mRNA stability GO:0044528
Any process that modulates the propensity of mitochondrial mRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial mRNAs.
4 Q5U1D1 (/IMP) Q8IH29 (/IMP) Q95RX7 (/IMP) Q9V9X7 (/IMP)
Mitochondrial RNA catabolic process GO:0000957
The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.
1 Q9S7G6 (/IMP)
Mitochondrial RNA processing GO:0000963
The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion.
1 Q9S7G6 (/IMP)
RNA catabolic process GO:0006401
The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
1 Q8GZQ3 (/IMP)
Negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway GO:0010323
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent).
1 Q8GZQ3 (/IMP)
Chlorophyll biosynthetic process GO:0015995
The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.
1 Q8GZQ3 (/IMP)
Cellular response to phosphate starvation GO:0016036
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.
1 Q8GZQ3 (/IMP)
Carotene biosynthetic process GO:0016120
The chemical reactions and pathways resulting in the formation of carotenes, hydrocarbon carotenoids.
1 Q8GZQ3 (/IMP)
Xanthophyll biosynthetic process GO:0016123
The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids.
1 Q8GZQ3 (/IMP)
Chloroplast RNA processing GO:0031425
The conversion of a primary RNA molecule transcribed from a chloroplast genome into one or more mature RNA molecules.
1 Q8GZQ3 (/IMP)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
29 P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA)
(19 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
21 O51745 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA)
(11 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
20 P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA)
(10 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
9 P9WI57 (/HDA) P9WI57 (/HDA) P9WI57 (/HDA) P9WI57 (/HDA) P9WI57 (/HDA) P9WI57 (/HDA) P9WI57 (/HDA) P9WI57 (/HDA) P9WI57 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
9 P9WI57 (/HDA) P9WI57 (/HDA) P9WI57 (/HDA) P9WI57 (/HDA) P9WI57 (/HDA) P9WI57 (/HDA) P9WI57 (/HDA) P9WI57 (/HDA) P9WI57 (/HDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
1 Q8GZQ3 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
1 Q8GZQ3 (/IDA)
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