The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"PurM-like, N-terminal domain
".
FunFam 2: Phosphoribosylformylglycinamidine synthase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Phosphoribosylformylglycinamidine synthase activity GO:0004642
Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H(2)O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H(+) + phosphate.
|
15 |
Q48LX3 (/ISS)
Q48LX3 (/ISS)
Q48LX3 (/ISS)
Q60B11 (/ISS)
Q886W6 (/ISS)
Q886W6 (/ISS)
Q886W6 (/ISS)
Q8EC57 (/ISS)
Q9KTN2 (/ISS)
Q9KTN2 (/ISS)
(5 more) |
Phosphoribosylformylglycinamidine synthase activity GO:0004642
Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H(2)O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H(+) + phosphate.
|
11 |
P15254 (/IMP)
P15254 (/IMP)
P15254 (/IMP)
P15254 (/IMP)
P15254 (/IMP)
P15254 (/IMP)
P15254 (/IMP)
P15254 (/IMP)
P38972 (/IMP)
P38972 (/IMP)
(1 more) |
Phosphoribosylformylglycinamidine synthase activity GO:0004642
Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H(2)O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H(+) + phosphate.
|
8 | P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
8 | P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) |
ATPase activity, coupled GO:0042623
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane.
|
8 | P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) |
Phosphoribosylformylglycinamidine synthase activity GO:0004642
Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H(2)O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H(+) + phosphate.
|
2 | Q5AUA9 (/RCA) Q5AUA9 (/RCA) |
Phosphoribosylformylglycinamidine synthase activity GO:0004642
Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H(2)O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H(+) + phosphate.
|
1 | O14228 (/ISO) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Purine ribonucleotide biosynthetic process GO:0009152
The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
|
15 |
Q48LX3 (/ISS)
Q48LX3 (/ISS)
Q48LX3 (/ISS)
Q60B11 (/ISS)
Q886W6 (/ISS)
Q886W6 (/ISS)
Q886W6 (/ISS)
Q8EC57 (/ISS)
Q9KTN2 (/ISS)
Q9KTN2 (/ISS)
(5 more) |
'de novo' IMP biosynthetic process GO:0006189
The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate.
|
11 |
P15254 (/IC)
P15254 (/IC)
P15254 (/IC)
P15254 (/IC)
P15254 (/IC)
P15254 (/IC)
P15254 (/IC)
P15254 (/IC)
P38972 (/IC)
P38972 (/IC)
(1 more) |
Glutamine metabolic process GO:0006541
The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.
|
8 | P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) |
Purine nucleotide biosynthetic process GO:0006164
The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
|
3 | P38972 (/IMP) P38972 (/IMP) P38972 (/IMP) |
Nucleobase-containing compound metabolic process GO:0006139
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
|
2 | Q5AUA9 (/RCA) Q5AUA9 (/RCA) |
'de novo' IMP biosynthetic process GO:0006189
The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate.
|
1 | O14228 (/EXP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
8 | P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
8 | P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) P15254 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | O14228 (/HDA) P38972 (/HDA) P38972 (/HDA) P38972 (/HDA) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
1 | O14228 (/HDA) |