The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
PurM-like, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Phosphoribosylformylglycinamidine cyclo-ligase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphoribosylformylglycinamidine cyclo-ligase. [EC: 6.3.3.1]
ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.
    15750 A0A023P0W7 A0A023P0W7 A0A023P0W7 A0A023P0W7 A0A023P0W7 A0A023P0W7 A0A023P0W7 A0A023P0W7 A0A023P0W7 A0A023P0W7
    (15740 more...)
    Phosphoribosylamine--glycine ligase. [EC: 6.3.4.13]
    ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)- (5-phospho-D-ribosyl)glycinamide.
    • Formerly EC 6.3.1.3.
    48 A0A0L8VR11 A0A0L8VR11 A0A0L8VR11 A0A0L8VR11 A0A0L8VR11 A0A0L8VR11 A0A1D8NPD9 A0A1D8NPD9 A6ZTV6 A6ZTV6
    (38 more...)
    Phosphoribosylglycinamide formyltransferase. [EC: 2.1.2.2]
    10-formyltetrahydrofolate + N(1)-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide.
      6 P00967 P16340 P21872 P22102 Q59A32 Q64737