The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribosome maturation protein SBDS, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: SBDS, ribosome maturation factor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
22 A5D8M6 (/ISS) P70122 (/ISS) Q3SWZ6 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS)
(12 more)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
16 B5XEK1 (/ISS) Q3SWZ6 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS)
(6 more)
RRNA binding GO:0019843
Interacting selectively and non-covalently with ribosomal RNA.
16 B5XEK1 (/ISS) Q3SWZ6 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS)
(6 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
14 Q9Y3A5 (/HDA) Q9Y3A5 (/HDA) Q9Y3A5 (/HDA) Q9Y3A5 (/HDA) Q9Y3A5 (/HDA) Q9Y3A5 (/HDA) Q9Y3A5 (/HDA) Q9Y3A5 (/HDA) Q9Y3A5 (/HDA) Q9Y3A5 (/HDA)
(4 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
14 Q9Y3A5 (/IPI) Q9Y3A5 (/IPI) Q9Y3A5 (/IPI) Q9Y3A5 (/IPI) Q9Y3A5 (/IPI) Q9Y3A5 (/IPI) Q9Y3A5 (/IPI) Q9Y3A5 (/IPI) Q9Y3A5 (/IPI) Q9Y3A5 (/IPI)
(4 more)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
14 Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA)
(4 more)
RRNA binding GO:0019843
Interacting selectively and non-covalently with ribosomal RNA.
14 Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA)
(4 more)
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
14 Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA)
(4 more)
Guanyl-nucleotide exchange factor activity GO:0005085
Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
9 Q07953 (/IDA) Q07953 (/IDA) Q07953 (/IDA) Q07953 (/IDA) Q07953 (/IDA) Q07953 (/IDA) Q07953 (/IDA) Q07953 (/IDA) Q07953 (/IDA)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
2 Q9MAR2 (/ISS) Q9MAR2 (/ISS)
Guanyl-nucleotide exchange factor activity GO:0005085
Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
1 O14179 (/ISO)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
1 P70122 (/ISO)
RRNA binding GO:0019843
Interacting selectively and non-covalently with ribosomal RNA.
1 P70122 (/ISO)
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
1 P70122 (/ISO)

There are 29 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
22 A5D8M6 (/ISS) P70122 (/ISS) Q3SWZ6 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS)
(12 more)
Mature ribosome assembly GO:0042256
The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional ribosome.
22 A5D8M6 (/ISS) P70122 (/ISS) Q3SWZ6 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS)
(12 more)
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
19 B5XEK1 (/ISS) G4MNZ9 (/ISS) G4MNZ9 (/ISS) G4MNZ9 (/ISS) Q3SWZ6 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS)
(9 more)
Mitotic spindle organization GO:0007052
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
16 B5XEK1 (/ISS) Q3SWZ6 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS)
(6 more)
Bone mineralization GO:0030282
The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
16 B5XEK1 (/ISS) Q3SWZ6 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS)
(6 more)
Leukocyte chemotaxis GO:0030595
The movement of a leukocyte in response to an external stimulus.
16 B5XEK1 (/ISS) Q3SWZ6 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS)
(6 more)
Bone marrow development GO:0048539
The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure.
16 B5XEK1 (/ISS) Q3SWZ6 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS)
(6 more)
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
14 Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP)
(4 more)
Mitotic spindle organization GO:0007052
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
14 Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA)
(4 more)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
14 Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP)
(4 more)
Bone mineralization GO:0030282
The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
14 Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP)
(4 more)
Leukocyte chemotaxis GO:0030595
The movement of a leukocyte in response to an external stimulus.
14 Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA)
(4 more)
Mature ribosome assembly GO:0042256
The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional ribosome.
14 Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA)
(4 more)
Bone marrow development GO:0048539
The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure.
14 Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP) Q9Y3A5 (/IMP)
(4 more)
Mature ribosome assembly GO:0042256
The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional ribosome.
9 Q07953 (/IMP) Q07953 (/IMP) Q07953 (/IMP) Q07953 (/IMP) Q07953 (/IMP) Q07953 (/IMP) Q07953 (/IMP) Q07953 (/IMP) Q07953 (/IMP)
Myeloid leukocyte differentiation GO:0002573
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage.
3 F8W4Y5 (/IMP) F8W5Q9 (/IMP) Q7ZW65 (/IMP)
Granulocyte differentiation GO:0030851
The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.
3 F8W4Y5 (/IMP) F8W5Q9 (/IMP) Q7ZW65 (/IMP)
Exocrine pancreas development GO:0031017
The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells.
3 F8W4Y5 (/IMP) F8W5Q9 (/IMP) Q7ZW65 (/IMP)
Ribosome biogenesis GO:0042254
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
3 F8W4Y5 (/IMP) F8W5Q9 (/IMP) Q7ZW65 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
2 Q9MAR2 (/TAS) Q9MAR2 (/TAS)
Inner cell mass cell proliferation GO:0001833
The proliferation of cells in the inner cell mass.
1 P70122 (/IMP)
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
1 P70122 (/ISO)
Mitotic spindle organization GO:0007052
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
1 P70122 (/ISO)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
1 P70122 (/ISO)
Bone mineralization GO:0030282
The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
1 P70122 (/ISO)
Leukocyte chemotaxis GO:0030595
The movement of a leukocyte in response to an external stimulus.
1 P70122 (/ISO)
Ribosome biogenesis GO:0042254
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
1 O14179 (/ISO)
Mature ribosome assembly GO:0042256
The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional ribosome.
1 P70122 (/ISO)
Bone marrow development GO:0048539
The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure.
1 P70122 (/ISO)

There are 20 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
29 A0A087X020 (/IDA) A0A0S2Z5I7 (/IDA) A0A0S2Z5I7 (/IDA) A0A0S2Z5I7 (/IDA) A0A0S2Z5I7 (/IDA) A0A0S2Z5I7 (/IDA) A0A0S2Z5I7 (/IDA) A0A0S2Z5I7 (/IDA) A0A0S2Z5I7 (/IDA) A0A0S2Z5I7 (/IDA)
(19 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
29 A0A087X020 (/IDA) A0A0S2Z5I7 (/IDA) A0A0S2Z5I7 (/IDA) A0A0S2Z5I7 (/IDA) A0A0S2Z5I7 (/IDA) A0A0S2Z5I7 (/IDA) A0A0S2Z5I7 (/IDA) A0A0S2Z5I7 (/IDA) A0A0S2Z5I7 (/IDA) A0A0S2Z5I7 (/IDA)
(19 more)
Spindle pole GO:0000922
Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
23 A5D8M6 (/ISS) B5XEK1 (/ISS) P70122 (/ISS) Q3SWZ6 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS)
(13 more)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
19 B5XEK1 (/ISS) G4MNZ9 (/ISS) G4MNZ9 (/ISS) G4MNZ9 (/ISS) Q3SWZ6 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS)
(9 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
19 B5XEK1 (/ISS) G4MNZ9 (/ISS) G4MNZ9 (/ISS) G4MNZ9 (/ISS) Q3SWZ6 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS) Q5RAZ2 (/ISS)
(9 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
15 Q86KZ5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA)
(5 more)
Spindle pole GO:0000922
Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
14 Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA)
(4 more)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
14 Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA) Q9Y3A5 (/IDA)
(4 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
10 O14179 (/HDA) Q07953 (/HDA) Q07953 (/HDA) Q07953 (/HDA) Q07953 (/HDA) Q07953 (/HDA) Q07953 (/HDA) Q07953 (/HDA) Q07953 (/HDA) Q07953 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
9 Q07953 (/HDA) Q07953 (/HDA) Q07953 (/HDA) Q07953 (/HDA) Q07953 (/HDA) Q07953 (/HDA) Q07953 (/HDA) Q07953 (/HDA) Q07953 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 G4MNZ9 (/ISS) G4MNZ9 (/ISS) G4MNZ9 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 G4MNZ9 (/ISS) G4MNZ9 (/ISS) G4MNZ9 (/ISS)
Spindle pole GO:0000922
Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
1 P70122 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P70122 (/ISO)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 O14179 (/HDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 P70122 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P70122 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O14179 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P70122 (/ISO)
Preribosome, large subunit precursor GO:0030687
A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit.
1 O14179 (/ISO)