The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: GTP cyclohydrolase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 27 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTP cyclohydrolase I activity GO:0003934
Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate.
198 P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA)
(188 more)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
194 P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA)
(184 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
194 P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA)
(184 more)
GTP cyclohydrolase I activity GO:0003934
Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate.
12 P51601 (/IMP) P51601 (/IMP) P51601 (/IMP) P51601 (/IMP) P51601 (/IMP) P51601 (/IMP) P51601 (/IMP) P51601 (/IMP) P51601 (/IMP) P51601 (/IMP)
(2 more)
GTP cyclohydrolase I activity GO:0003934
Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate.
11 Q19980 (/ISS) Q19980 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS)
(1 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 P22288 (/IPI) P30793 (/IPI) P30793 (/IPI) P30793 (/IPI) P30793 (/IPI) P30793 (/IPI) Q19980 (/IPI) Q19980 (/IPI)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
5 P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
5 P30793 (/IPI) P30793 (/IPI) P30793 (/IPI) P30793 (/IPI) P30793 (/IPI)
Mitogen-activated protein kinase binding GO:0051019
Interacting selectively and non-covalently with a mitogen-activated protein kinase.
5 P30793 (/IPI) P30793 (/IPI) P30793 (/IPI) P30793 (/IPI) P30793 (/IPI)
GTP cyclohydrolase I activity GO:0003934
Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate.
3 O13774 (/ISO) Q05915 (/ISO) Q05915 (/ISO)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
2 Q05915 (/ISO) Q05915 (/ISO)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
2 Q05915 (/ISO) Q05915 (/ISO)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
2 Q05915 (/ISO) Q05915 (/ISO)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
2 Q05915 (/ISO) Q05915 (/ISO)
GTP-dependent protein binding GO:0030742
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) when at least one of the interacting partners is in the GTP-bound state.
2 Q05915 (/ISO) Q05915 (/ISO)
Translation initiation factor binding GO:0031369
Interacting selectively and non-covalently with a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation.
2 Q05915 (/ISO) Q05915 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q05915 (/ISO) Q05915 (/ISO)
Coenzyme binding GO:0050662
Interacting selectively and non-covalently with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
2 Q05915 (/ISO) Q05915 (/ISO)
Mitogen-activated protein kinase binding GO:0051019
Interacting selectively and non-covalently with a mitogen-activated protein kinase.
2 Q05915 (/ISO) Q05915 (/ISO)
GTP cyclohydrolase activity GO:0003933
Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized.
1 P50141 (/IDA)
GTP cyclohydrolase activity GO:0003933
Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized.
1 P50141 (/IMP)
GTP cyclohydrolase I activity GO:0003934
Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate.
1 C8V749 (/RCA)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 P22288 (/IDA)
GTP-dependent protein binding GO:0030742
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) when at least one of the interacting partners is in the GTP-bound state.
1 P22288 (/IPI)
Translation initiation factor binding GO:0031369
Interacting selectively and non-covalently with a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation.
1 P22288 (/IPI)
Coenzyme binding GO:0050662
Interacting selectively and non-covalently with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
1 P22288 (/IDA)
GTP cyclohydrolase I regulator activity GO:0060308
Modulates the activity of GTP cyclohydrolase I. GTP cyclohydrolase I activity catalyzes the reaction: GTP + 2 H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.
1 P48596 (/IDA)

There are 64 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Queuosine biosynthetic process GO:0008616
The chemical reactions and pathways resulting in the formation of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.
188 P0A6T5 (/IMP) P0A6T5 (/IMP) P0A6T5 (/IMP) P0A6T5 (/IMP) P0A6T5 (/IMP) P0A6T5 (/IMP) P0A6T5 (/IMP) P0A6T5 (/IMP) P0A6T5 (/IMP) P0A6T5 (/IMP)
(178 more)
Folic acid-containing compound biosynthetic process GO:0009396
The chemical reactions and pathways resulting in the formation of folic acid and its derivatives.
10 P51601 (/IMP) P51601 (/IMP) P51601 (/IMP) P51601 (/IMP) P51601 (/IMP) P51601 (/IMP) P51601 (/IMP) P51601 (/IMP) P51601 (/IMP) P51601 (/IMP)
Folic acid-containing compound metabolic process GO:0006760
The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units.
9 Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS)
Tetrahydrobiopterin biosynthetic process GO:0006729
The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.
8 P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P48596 (/IDA) P50141 (/IDA) Q94465 (/IDA)
Tetrahydrobiopterin biosynthetic process GO:0006729
The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.
8 P30793 (/IMP) P30793 (/IMP) P30793 (/IMP) P30793 (/IMP) P30793 (/IMP) P50141 (/IMP) Q19980 (/IMP) Q19980 (/IMP)
Regulation of blood pressure GO:0008217
Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.
7 P30793 (/IMP) P30793 (/IMP) P30793 (/IMP) P30793 (/IMP) P30793 (/IMP) Q05915 (/IMP) Q05915 (/IMP)
Response to pain GO:0048265
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.
7 P30793 (/ISS) P30793 (/ISS) P30793 (/ISS) P30793 (/ISS) P30793 (/ISS) Q05915 (/ISS) Q05915 (/ISS)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
6 P22288 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA)
Nitric oxide biosynthetic process GO:0006809
The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.
5 P30793 (/NAS) P30793 (/NAS) P30793 (/NAS) P30793 (/NAS) P30793 (/NAS)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
5 P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA)
Response to interferon-gamma GO:0034341
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon.
5 P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA)
Response to tumor necrosis factor GO:0034612
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
5 P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA)
Dopamine biosynthetic process GO:0042416
The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
5 P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA)
Pteridine-containing compound biosynthetic process GO:0042559
The chemical reactions and pathways resulting in the formation of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.
5 P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA)
Neuromuscular process controlling posture GO:0050884
Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts.
5 P30793 (/IMP) P30793 (/IMP) P30793 (/IMP) P30793 (/IMP) P30793 (/IMP)
Positive regulation of nitric-oxide synthase activity GO:0051000
Any process that activates or increases the activity of the enzyme nitric-oxide synthase.
5 P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA)
Positive regulation of nitric-oxide synthase activity GO:0051000
Any process that activates or increases the activity of the enzyme nitric-oxide synthase.
5 P30793 (/IMP) P30793 (/IMP) P30793 (/IMP) P30793 (/IMP) P30793 (/IMP)
Cofactor metabolic process GO:0051186
The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
5 P30793 (/TAS) P30793 (/TAS) P30793 (/TAS) P30793 (/TAS) P30793 (/TAS)
Regulation of removal of superoxide radicals GO:2000121
Any process that modulates the frequency, rate or extent of removal of superoxide radicals.
5 P30793 (/IMP) P30793 (/IMP) P30793 (/IMP) P30793 (/IMP) P30793 (/IMP)
Dopamine biosynthetic process from tyrosine GO:0006585
The chemical reactions and pathways resulting in the formation of dopamine (3,4-dihydroxyphenylethylamine) from L-tyrosine, via the metabolic precursor 3,4-dihydroxy-L-phenylalanine (L-dopa). Dopamine is a catecholamine neurotransmitter and a metabolic precursor of norepinephrine and epinephrine.
2 Q19980 (/IMP) Q19980 (/IMP)
Tetrahydrobiopterin biosynthetic process GO:0006729
The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.
2 Q05915 (/IC) Q05915 (/IC)
Tetrahydrobiopterin biosynthetic process GO:0006729
The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.
2 Q05915 (/ISO) Q05915 (/ISO)
Tetrahydrobiopterin biosynthetic process GO:0006729
The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.
2 Q19980 (/ISS) Q19980 (/ISS)
Regulation of blood pressure GO:0008217
Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.
2 Q05915 (/ISO) Q05915 (/ISO)
Positive regulation of heart rate GO:0010460
Any process that activates or increases the frequency or rate of heart contraction.
2 Q05915 (/IMP) Q05915 (/IMP)
Regulation of lung blood pressure GO:0014916
The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure.
2 Q05915 (/IMP) Q05915 (/IMP)
Response to interferon-gamma GO:0034341
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon.
2 Q05915 (/ISO) Q05915 (/ISO)
Response to tumor necrosis factor GO:0034612
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
2 Q05915 (/ISO) Q05915 (/ISO)
Vasodilation GO:0042311
An increase in the internal diameter of blood vessels, especially arterioles or capillaries, due to relaxation of smooth muscle cells that line the vessels, and usually resulting in a decrease in blood pressure.
2 Q05915 (/ISO) Q05915 (/ISO)
Dopamine biosynthetic process GO:0042416
The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
2 Q05915 (/ISO) Q05915 (/ISO)
Melanin biosynthetic process GO:0042438
The chemical reactions and pathways resulting in the formation of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.
2 Q19980 (/IMP) Q19980 (/IMP)
Pteridine-containing compound biosynthetic process GO:0042559
The chemical reactions and pathways resulting in the formation of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.
2 Q05915 (/ISO) Q05915 (/ISO)
Negative regulation of blood pressure GO:0045776
Any process in which the force of blood traveling through the circulatory system is decreased.
2 Q05915 (/ISO) Q05915 (/ISO)
Response to pain GO:0048265
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.
2 Q05915 (/ISO) Q05915 (/ISO)
Neuromuscular process controlling posture GO:0050884
Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts.
2 Q05915 (/ISO) Q05915 (/ISO)
Positive regulation of nitric-oxide synthase activity GO:0051000
Any process that activates or increases the activity of the enzyme nitric-oxide synthase.
2 Q05915 (/ISO) Q05915 (/ISO)
Dihydrobiopterin metabolic process GO:0051066
The chemical reactions and pathways involving a dihydrobiopterin, a reduced pteridine derivative related to folic acid; it acts as an electron carrier in tyrosine biosynthesis and its quinoid form is produced by oxidation of tetrahydrobiopterin in several biological hydroxylation reactions.
2 Q05915 (/ISO) Q05915 (/ISO)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
2 Q05915 (/ISO) Q05915 (/ISO)
Protein heterooligomerization GO:0051291
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
2 Q05915 (/ISO) Q05915 (/ISO)
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
2 Q05915 (/ISO) Q05915 (/ISO)
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
2 Q05915 (/TAS) Q05915 (/TAS)
Regulation of serotonin biosynthetic process GO:1905627
Any process that modulates the frequency, rate or extent of serotonin biosynthetic process.
2 Q05915 (/NAS) Q05915 (/NAS)
Regulation of removal of superoxide radicals GO:2000121
Any process that modulates the frequency, rate or extent of removal of superoxide radicals.
2 Q05915 (/ISO) Q05915 (/ISO)
Pteridine biosynthetic process GO:0006728
The chemical reactions and pathways resulting in the formation of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.
1 P48596 (/IC)
Pteridine biosynthetic process GO:0006728
The chemical reactions and pathways resulting in the formation of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.
1 P48596 (/IMP)
Tetrahydrobiopterin biosynthetic process GO:0006729
The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.
1 P22288 (/TAS)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 Q94465 (/IDA)
Regulation of G protein-coupled receptor signaling pathway GO:0008277
Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway.
1 Q94465 (/IDA)
Larval chitin-based cuticle development GO:0008363
Synthesis and deposition of a chitin-based larval cuticle. The insect larval cuticle is a secretion from epidermal cells that is shed at each molt. An example of this is found in Drosophila melanogaster.
1 P48596 (/IMP)
Embryonic pattern specification GO:0009880
The process that results in the patterns of cell differentiation that will arise in an embryo.
1 P48596 (/IMP)
Preblastoderm mitotic cell cycle GO:0035185
The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. This is the first phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis.
1 P48596 (/IMP)
Vasodilation GO:0042311
An increase in the internal diameter of blood vessels, especially arterioles or capillaries, due to relaxation of smooth muscle cells that line the vessels, and usually resulting in a decrease in blood pressure.
1 P22288 (/IMP)
Regulation of GTP cyclohydrolase I activity GO:0043095
Any process that modulates the activity of the enzyme GTP cyclohydrolase I.
1 P48596 (/IDA)
Positive regulation of nitric oxide biosynthetic process GO:0045429
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
1 P50141 (/IDA)
Negative regulation of blood pressure GO:0045776
Any process in which the force of blood traveling through the circulatory system is decreased.
1 P22288 (/IMP)
Folic acid biosynthetic process GO:0046656
The chemical reactions and pathways resulting in the formation of folic acid, pteroylglutamic acid.
1 O13774 (/IC)
Folic acid biosynthetic process GO:0046656
The chemical reactions and pathways resulting in the formation of folic acid, pteroylglutamic acid.
1 C8V749 (/RCA)
Cuticle pigmentation GO:0048067
Establishment of a pattern of pigment in the cuticle of an organism.
1 P48596 (/IMP)
Compound eye pigmentation GO:0048072
Establishment of a pattern of pigment in the compound eye.
1 P48596 (/IMP)
Response to pain GO:0048265
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.
1 P22288 (/IDA)
Dihydrobiopterin metabolic process GO:0051066
The chemical reactions and pathways involving a dihydrobiopterin, a reduced pteridine derivative related to folic acid; it acts as an electron carrier in tyrosine biosynthesis and its quinoid form is produced by oxidation of tetrahydrobiopterin in several biological hydroxylation reactions.
1 P22288 (/IDA)
Protein heterooligomerization GO:0051291
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 P22288 (/IDA)
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
1 P22288 (/IDA)
Regulation of epithelial cell migration, open tracheal system GO:2000274
Any process that modulates the frequency, rate or extent of epithelial cell migration, open tracheal system.
1 P48596 (/IMP)

There are 21 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
198 A0A024R642 (/IDA) A0A024R642 (/IDA) A0A024R642 (/IDA) A0A024R642 (/IDA) A0A024R642 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA)
(188 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
196 P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA)
(186 more)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
194 P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA)
(184 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
11 O13774 (/HDA) P51601 (/HDA) P51601 (/HDA) P51601 (/HDA) P51601 (/HDA) P51601 (/HDA) P51601 (/HDA) P51601 (/HDA) P51601 (/HDA) P51601 (/HDA)
(1 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
10 A0A024R642 (/IDA) A0A024R642 (/IDA) A0A024R642 (/IDA) A0A024R642 (/IDA) A0A024R642 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
10 P51601 (/HDA) P51601 (/HDA) P51601 (/HDA) P51601 (/HDA) P51601 (/HDA) P51601 (/HDA) P51601 (/HDA) P51601 (/HDA) P51601 (/HDA) P51601 (/HDA)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
10 A0A024R642 (/IDA) A0A024R642 (/IDA) A0A024R642 (/IDA) A0A024R642 (/IDA) A0A024R642 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 P30793 (/TAS) P30793 (/TAS) P30793 (/TAS) P30793 (/TAS) P30793 (/TAS)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
5 P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA) P30793 (/IDA)
Neuron projection terminus GO:0044306
The specialized, terminal region of a neuron projection such as an axon or a dendrite.
5 P30793 (/TAS) P30793 (/TAS) P30793 (/TAS) P30793 (/TAS) P30793 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q05915 (/ISO) Q05915 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 Q05915 (/ISO) Q05915 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q05915 (/ISO) Q05915 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q05915 (/ISO) Q05915 (/ISO)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
2 Q05915 (/ISO) Q05915 (/ISO)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
2 Q05915 (/ISO) Q05915 (/ISO)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
2 Q05915 (/ISO) Q05915 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O13774 (/HDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q94465 (/IDA)
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
1 Q94465 (/HDA)