The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
POLO box domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 10: Serine/threonine-protein kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
5 P32562 (/HDA) P32562 (/HDA) P32562 (/HDA) P32562 (/HDA) P32562 (/HDA)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
5 P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
5 P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 P32562 (/IPI) P32562 (/IPI) P32562 (/IPI) P32562 (/IPI) P32562 (/IPI)
Centromeric DNA binding GO:0019237
Interacting selectively and non-covalently with a centromere, a region of chromosome where the spindle fibers attach during mitosis and meiosis.
5 P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
5 P32562 (/IPI) P32562 (/IPI) P32562 (/IPI) P32562 (/IPI) P32562 (/IPI)
Phosphoprotein binding GO:0051219
Interacting selectively and non-covalently with a phosphorylated protein.
5 P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA)

There are 20 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Resolution of meiotic recombination intermediates GO:0000712
The cleavage and rejoining of intermediates, such as Holliday junctions, formed during meiotic recombination to produce two intact molecules in which genetic material has been exchanged.
5 P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
5 P32562 (/HDA) P32562 (/HDA) P32562 (/HDA) P32562 (/HDA) P32562 (/HDA)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
5 P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
5 P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
5 P32562 (/IPI) P32562 (/IPI) P32562 (/IPI) P32562 (/IPI) P32562 (/IPI)
Exit from mitosis GO:0010458
The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
5 P32562 (/IGI) P32562 (/IGI) P32562 (/IGI) P32562 (/IGI) P32562 (/IGI)
Positive regulation of mitotic spindle pole body separation GO:0010696
Any process that increases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.
5 P32562 (/IGI) P32562 (/IGI) P32562 (/IGI) P32562 (/IGI) P32562 (/IGI)
Positive regulation of mitotic spindle pole body separation GO:0010696
Any process that increases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.
5 P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP)
Positive regulation of Rho protein signal transduction GO:0035025
Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction.
5 P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP)
Synaptonemal complex disassembly GO:0070194
The controlled breakdown of a synaptonemal complex.
5 P32562 (/IGI) P32562 (/IGI) P32562 (/IGI) P32562 (/IGI) P32562 (/IGI)
Spindle assembly involved in meiosis GO:0090306
The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis.
5 P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP)
Positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly GO:0110083
Any process that activates or increases the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.
5 P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP)
Regulation of protein localization to mitotic spindle pole body GO:1902542
Any process that modulates the frequency, rate or extent of protein localization to mitotic spindle pole body.
5 P32562 (/IGI) P32562 (/IGI) P32562 (/IGI) P32562 (/IGI) P32562 (/IGI)
Regulation of nucleus organization GO:1903353
Any process that modulates the frequency, rate or extent of nucleus organization.
5 P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP) P32562 (/IMP)
Signal transduction involved in filamentous growth GO:0001402
Relaying of environmental signals promoting filamentous growth.
2 Q5ABG0 (/IMP) Q5ABG0 (/IMP)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
2 Q5ABG0 (/IMP) Q5ABG0 (/IMP)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
2 Q5ABG0 (/IMP) Q5ABG0 (/IMP)
Filamentous growth of a population of unicellular organisms in response to starvation GO:0036170
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
2 Q5ABG0 (/IMP) Q5ABG0 (/IMP)
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
2 Q5ABG0 (/IMP) Q5ABG0 (/IMP)
Filamentous growth of a population of unicellular organisms GO:0044182
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.
2 Q5ABG0 (/IMP) Q5ABG0 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
7 P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) Q5ABG0 (/IDA) Q5ABG0 (/IDA)
Spindle pole GO:0000922
Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
5 P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA) P32562 (/IDA)
Nuclear chromosome GO:0000228
A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.
2 Q5ABG0 (/IDA) Q5ABG0 (/IDA)
Spindle pole body GO:0005816
The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.
2 Q5ABG0 (/IDA) Q5ABG0 (/IDA)
Spindle GO:0005819
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
2 Q5ABG0 (/IDA) Q5ABG0 (/IDA)
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