The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Phosphatidylinositol 3-kinase catalytic subunit ty...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 O88763 (/IPI) P42339 (/IPI) Q6PF93 (/IPI) Q8NEB9 (/IPI) Q8NEB9 (/IPI) Q8NEB9 (/IPI) Q8NEB9 (/IPI)
1-phosphatidylinositol-3-kinase activity GO:0016303
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+).
6 P91635 (/ISS) Q5D891 (/ISS) Q6AZN6 (/ISS) Q6AZN6 (/ISS) Q6PF93 (/ISS) Q9W1M7 (/ISS)
1-phosphatidylinositol-3-kinase activity GO:0016303
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+).
5 A0A1D8PDV7 (/IDA) O88763 (/IDA) P50520 (/IDA) P91635 (/IDA) Q9W1M7 (/IDA)
1-phosphatidylinositol-3-kinase activity GO:0016303
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+).
5 P50520 (/IMP) Q8NEB9 (/IMP) Q8NEB9 (/IMP) Q8NEB9 (/IMP) Q8NEB9 (/IMP)
Kinase activity GO:0016301
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
4 Q8NEB9 (/IDA) Q8NEB9 (/IDA) Q8NEB9 (/IDA) Q8NEB9 (/IDA)
1-phosphatidylinositol-3-kinase activity GO:0016303
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+).
4 Q8NEB9 (/TAS) Q8NEB9 (/TAS) Q8NEB9 (/TAS) Q8NEB9 (/TAS)
1-phosphatidylinositol 4-kinase activity GO:0004430
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = 1-phosphatidyl-1D-myo-inositol 4-phosphate + ADP + 2 H(+).
2 Q5B421 (/RCA) Q5B421 (/RCA)
1-phosphatidylinositol-3-kinase activity GO:0016303
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+).
2 Q5B421 (/RCA) Q5B421 (/RCA)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
1 A0A1D8PDV7 (/IDA)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
1 Q6PF93 (/IMP)
Kinase activity GO:0016301
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
1 Q6PF93 (/ISO)
1-phosphatidylinositol-3-kinase activity GO:0016303
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+).
1 Q6PF93 (/ISO)
Phosphatidylinositol 3-kinase activity GO:0035004
Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to phosphatidylinositol or one of its phosphorylated derivatives at the 3' position of the inositol ring.
1 O88763 (/IMP)
Phosphatidylinositol 3-kinase activity GO:0035004
Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to phosphatidylinositol or one of its phosphorylated derivatives at the 3' position of the inositol ring.
1 Q6PF93 (/ISO)

There are 71 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Autophagy GO:0006914
The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
7 A0A1D8PDV7 (/IMP) P91635 (/IMP) Q8NEB9 (/IMP) Q8NEB9 (/IMP) Q8NEB9 (/IMP) Q8NEB9 (/IMP) Q9W1M7 (/IMP)
Macroautophagy GO:0016236
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
6 O88763 (/ISS) Q5D891 (/ISS) Q8NEB9 (/ISS) Q8NEB9 (/ISS) Q8NEB9 (/ISS) Q8NEB9 (/ISS)
Cellular response to glucose starvation GO:0042149
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.
6 O88763 (/ISS) Q5D891 (/ISS) Q8NEB9 (/ISS) Q8NEB9 (/ISS) Q8NEB9 (/ISS) Q8NEB9 (/ISS)
Regulation of cytokinesis GO:0032465
Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.
5 O88763 (/ISS) Q5D891 (/ISS) Q6AZN6 (/ISS) Q6AZN6 (/ISS) Q6PF93 (/ISS)
Protein lipidation GO:0006497
The covalent attachment of lipid groups to an amino acid in a protein.
4 Q8NEB9 (/IMP) Q8NEB9 (/IMP) Q8NEB9 (/IMP) Q8NEB9 (/IMP)
Phosphatidylinositol biosynthetic process GO:0006661
The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
4 Q8NEB9 (/TAS) Q8NEB9 (/TAS) Q8NEB9 (/TAS) Q8NEB9 (/TAS)
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
4 A0A1D8PDV7 (/IMP) P42339 (/IMP) P91635 (/IMP) Q9W1M7 (/IMP)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
4 A0A1D8PDV7 (/IMP) P91635 (/IMP) Q6PF93 (/IMP) Q9W1M7 (/IMP)
Macroautophagy GO:0016236
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
4 Q8NEB9 (/TAS) Q8NEB9 (/TAS) Q8NEB9 (/TAS) Q8NEB9 (/TAS)
Regulation of cytokinesis GO:0032465
Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.
4 Q8NEB9 (/IMP) Q8NEB9 (/IMP) Q8NEB9 (/IMP) Q8NEB9 (/IMP)
Toll-like receptor 9 signaling pathway GO:0034162
Any series of molecular signals generated as a consequence of binding to toll-like receptor 9.
4 Q8NEB9 (/TAS) Q8NEB9 (/TAS) Q8NEB9 (/TAS) Q8NEB9 (/TAS)
Early endosome to late endosome transport GO:0045022
The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.
4 Q8NEB9 (/IMP) Q8NEB9 (/IMP) Q8NEB9 (/IMP) Q8NEB9 (/IMP)
Early endosome to late endosome transport GO:0045022
The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.
3 O88763 (/ISS) Q5D891 (/ISS) Q6PF93 (/ISS)
Phosphatidylinositol phosphorylation GO:0046854
The process of introducing one or more phosphate groups into a phosphatidylinositol, any glycerophosphoinositol having one phosphatidyl group esterified to one of the hydroxy groups of inositol.
3 A0A1D8PDV7 (/IDA) P91635 (/IDA) Q9W1M7 (/IDA)
Autophagosome assembly GO:0000045
The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.
2 O88763 (/IMP) Q6PF93 (/IMP)
Phospholipid metabolic process GO:0006644
The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.
2 Q5B421 (/RCA) Q5B421 (/RCA)
Autophagy GO:0006914
The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
2 P91635 (/IGI) Q9W1M7 (/IGI)
Regulation of autophagy GO:0010506
Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
2 P91635 (/IMP) Q9W1M7 (/IMP)
Phosphatidylinositol 3-kinase signaling GO:0014065
A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.
2 A5PJQ9 (/IMP) F1MTL5 (/IMP)
Neuron remodeling GO:0016322
The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development.
2 P91635 (/IMP) Q9W1M7 (/IMP)
DsRNA transport GO:0033227
The directed movement of dsRNA, double-stranded ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P91635 (/IMP) Q9W1M7 (/IMP)
Larval midgut cell programmed cell death GO:0035096
The stage-specific programmed cell death of cells of the larval midgut, during histolysis of the larval organ.
2 P91635 (/IMP) Q9W1M7 (/IMP)
Positive regulation of nurse cell apoptotic process GO:0045850
Any process that activates or increases the frequency, rate or extent of nurse cell apoptotic process.
2 P91635 (/IMP) Q9W1M7 (/IMP)
Phosphatidylinositol phosphorylation GO:0046854
The process of introducing one or more phosphate groups into a phosphatidylinositol, any glycerophosphoinositol having one phosphatidyl group esterified to one of the hydroxy groups of inositol.
2 P91635 (/ISS) Q9W1M7 (/ISS)
Positive regulation of cell maturation GO:1903431
Any process that activates or increases the frequency, rate or extent of cell maturation.
2 A5PJQ9 (/IMP) F1MTL5 (/IMP)
Autophagosome assembly GO:0000045
The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.
1 Q6PF93 (/ISO)
Nuclear division GO:0000280
The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.
1 A0A1D8PDV7 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 A0A1D8PDV7 (/IDA)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 Q6PF93 (/IMP)
Protein lipidation GO:0006497
The covalent attachment of lipid groups to an amino acid in a protein.
1 Q6PF93 (/ISO)
Vacuolar protein processing GO:0006624
Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes.
1 A0A1D8PDV7 (/IMP)
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
1 P42339 (/IDA)
Autophagy GO:0006914
The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
1 Q6PF93 (/ISO)
Endosome organization GO:0007032
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
1 O88763 (/IMP)
Endosome organization GO:0007032
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
1 Q6PF93 (/ISO)
Vacuole organization GO:0007033
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.
1 A0A1D8PDV7 (/IMP)
Vacuolar transport GO:0007034
The directed movement of substances into, out of or within a vacuole.
1 A0A1D8PDV7 (/IMP)
Establishment or maintenance of cell polarity GO:0007163
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
1 Q9W1M7 (/IGI)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
1 A0A1D8PDV7 (/IMP)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
1 P42339 (/IMP)
Epithelial structure maintenance GO:0010669
A tissue homeostatic process required for the maintenance of epithelial structure.
1 Q9W1M7 (/IGI)
Vesicle-mediated transport GO:0016192
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
1 A0A1D8PDV7 (/IMP)
Macroautophagy GO:0016236
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
1 Q6PF93 (/IMP)
Protein processing GO:0016485
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
1 O88763 (/IMP)
Protein processing GO:0016485
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
1 Q6PF93 (/ISO)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
1 A0A1D8PDV7 (/IMP)
Nuclear migration along microtubule GO:0030473
The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins.
1 A0A1D8PDV7 (/IMP)
Ascospore-type prospore membrane assembly GO:0032120
The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed.
1 P50520 (/IMP)
Regulation of cytokinesis GO:0032465
Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.
1 Q6PF93 (/ISO)
Protein localization to phagophore assembly site GO:0034497
Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS).
1 Q6PF93 (/IMP)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 A0A1D8PDV7 (/IMP)
Phosphatidylinositol-3-phosphate biosynthetic process GO:0036092
The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position.
1 P50520 (/EXP)
Phosphatidylinositol-3-phosphate biosynthetic process GO:0036092
The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position.
1 P50520 (/IDA)
Phosphatidylinositol-3-phosphate biosynthetic process GO:0036092
The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position.
1 Q6PF93 (/IMP)
Filamentous growth of a population of unicellular organisms in response to starvation GO:0036170
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
1 A0A1D8PDV7 (/IMP)
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
1 A0A1D8PDV7 (/IMP)
Cellular response to glucose starvation GO:0042149
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.
1 Q6PF93 (/IDA)
Response to leucine GO:0043201
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus.
1 O88763 (/IEP)
Early endosome to late endosome transport GO:0045022
The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.
1 Q6PF93 (/ISO)
Phosphatidylinositol-mediated signaling GO:0048015
A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
1 P50520 (/IC)
Phosphatidylinositol-mediated signaling GO:0048015
A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
1 O88763 (/IDA)
Phosphatidylinositol-mediated signaling GO:0048015
A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
1 Q6PF93 (/ISO)
Regulation of protein secretion GO:0050708
Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.
1 O88763 (/IMP)
Regulation of protein secretion GO:0050708
Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.
1 Q6PF93 (/ISO)
Microgametogenesis GO:0055046
The process whose specific outcome is the progression of the pollen grain over time, from its formation as the microspore to the mature structure.
1 P42339 (/IMP)
Cellular response to osmotic stress GO:0071470
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
1 A0A1D8PDV7 (/IMP)
Reactive oxygen species metabolic process GO:0072593
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
1 P42339 (/IMP)
Protein localization to vacuole GO:0072665
A process in which a protein is transported to, or maintained at, a location in a vacuole.
1 P50520 (/IMP)
Positive regulation of ascospore formation GO:0075296
Any process that activates, maintains or increases the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus.
1 P50520 (/IMP)
Protein localization to prospore membrane GO:1902657
A process in which a protein is transported to, or maintained in, a location within a prospore membrane.
1 P50520 (/IMP)
Regulation of early endosome to late endosome transport GO:2000641
Any process that modulates the frequency, rate or extent of early endosome to late endosome transport.
1 Q9W1M7 (/IMP)

There are 25 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphatidylinositol 3-kinase complex, class III GO:0035032
A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Additional adaptor proteins may be present. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI).
6 O88763 (/ISS) Q5D891 (/ISS) Q8NEB9 (/ISS) Q8NEB9 (/ISS) Q8NEB9 (/ISS) Q8NEB9 (/ISS)
Axoneme GO:0005930
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
5 O88763 (/ISS) Q8NEB9 (/ISS) Q8NEB9 (/ISS) Q8NEB9 (/ISS) Q8NEB9 (/ISS)
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
5 O88763 (/ISS) Q5D891 (/ISS) Q6AZN6 (/ISS) Q6AZN6 (/ISS) Q6PF93 (/ISS)
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
4 Q8NEB9 (/IDA) Q8NEB9 (/IDA) Q8NEB9 (/IDA) Q8NEB9 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 Q8NEB9 (/TAS) Q8NEB9 (/TAS) Q8NEB9 (/TAS) Q8NEB9 (/TAS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
4 Q8NEB9 (/HDA) Q8NEB9 (/HDA) Q8NEB9 (/HDA) Q8NEB9 (/HDA)
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
4 Q8NEB9 (/IDA) Q8NEB9 (/IDA) Q8NEB9 (/IDA) Q8NEB9 (/IDA)
Phagocytic vesicle membrane GO:0030670
The lipid bilayer surrounding a phagocytic vesicle.
4 Q8NEB9 (/TAS) Q8NEB9 (/TAS) Q8NEB9 (/TAS) Q8NEB9 (/TAS)
Autolysosome GO:0044754
A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases.
4 Q8NEB9 (/IDA) Q8NEB9 (/IDA) Q8NEB9 (/IDA) Q8NEB9 (/IDA)
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
3 O88763 (/ISS) Q5D891 (/ISS) Q6PF93 (/ISS)
Autophagosome membrane GO:0000421
The lipid bilayer surrounding an autophagosome, a double-membrane-bounded vesicle in which endogenous cellular material is sequestered.
2 P91635 (/IDA) Q9W1M7 (/IDA)
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
2 P91635 (/IDA) Q9W1M7 (/IDA)
Phosphatidylinositol 3-kinase complex, class III, type I GO:0034271
A class III phosphatidylinositol 3-kinase complex that is involved in autophagy. In budding yeast, this complex consists of Vps30p, Vps34p, Apg14p and Vps15p.
2 P91635 (/IDA) Q9W1M7 (/IDA)
Phosphatidylinositol 3-kinase complex, class III GO:0035032
A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Additional adaptor proteins may be present. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI).
2 P91635 (/NAS) Q9W1M7 (/NAS)
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
1 P50520 (/IDA)
Prospore membrane GO:0005628
The prospore membrane is a double-membraned structure that extends from the cytoplasmic face of the spindle pole bodies to encompass the spindle pole bodies and the four nuclear lobes that are formed during meiosis. It helps isolate the meiotic nuclei from the cytoplasm during spore formation and serves as a foundation for the formation of the spore walls. An example of this component is found in Schizosaccharomyces pombe.
1 P50520 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P50520 (/HDA)
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
1 Q6PF93 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P50520 (/HDA)
Phosphatidylinositol 3-kinase complex GO:0005942
A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too.
1 P50520 (/IC)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 P50520 (/IMP)
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
1 Q6PF93 (/ISO)
Phosphatidylinositol 3-kinase complex, class III GO:0035032
A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Additional adaptor proteins may be present. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI).
1 Q6PF93 (/IDA)
Autolysosome GO:0044754
A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases.
1 Q6PF93 (/ISO)
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
1 Q6PF93 (/IDA)
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