The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13: Transmembrane serine/threonine-protein kinase B

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
10 P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
10 P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
10 P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
10 P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI)
Acetyltransferase activator activity GO:0010698
Binds to and increases the activity of an acetyltransferase, an enzyme which catalyzes the transfer of an acetyl group to an acceptor molecule.
10 P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
10 P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
10 P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
10 P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
10 P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP)
Peptidoglycan biosynthetic process GO:0009252
The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
10 P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA)
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
10 P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA)
Positive regulation of catalytic activity GO:0043085
Any process that activates or increases the activity of an enzyme.
10 P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA)
Negative regulation of catalytic activity GO:0043086
Any process that stops or reduces the activity of an enzyme.
10 P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA)
Positive regulation of DNA binding GO:0043388
Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
10 P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA)
Negative regulation of fatty acid biosynthetic process GO:0045717
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
10 P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA)
Negative regulation of growth rate GO:0045967
Any process that reduces the rate of growth of all or part of an organism.
10 P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP)
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
10 P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA)
Response to host immune response GO:0052572
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
10 P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
10 P9WI81 (/HDA) P9WI81 (/HDA) P9WI81 (/HDA) P9WI81 (/HDA) P9WI81 (/HDA) P9WI81 (/HDA) P9WI81 (/HDA) P9WI81 (/HDA) P9WI81 (/HDA) P9WI81 (/HDA)