CATH Superfamily 3.20.70.20
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 1: Ribonucleoside-diphosphate reductase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 13 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor GO:0004748
Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.
|
12 |
P21524 (/ISS)
P21524 (/ISS)
P23921 (/ISS)
P36602 (/ISS)
P36602 (/ISS)
P48591 (/ISS)
P79732 (/ISS)
Q03604 (/ISS)
Q5R919 (/ISS)
Q9SJ20 (/ISS)
(2 more) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | P07742 (/IPI) P21524 (/IPI) P21524 (/IPI) P23921 (/IPI) P36602 (/IPI) P36602 (/IPI) |
Ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor GO:0004748
Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.
|
3 | P07742 (/IDA) P21524 (/IDA) P21524 (/IDA) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
3 | P21524 (/IPI) P21524 (/IPI) P23921 (/IPI) |
Nucleotide binding GO:0000166
Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
|
2 | P21524 (/IDA) P21524 (/IDA) |
Nucleoside diphosphate kinase activity GO:0004550
Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
|
2 | P36602 (/IMP) P36602 (/IMP) |
Ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor GO:0004748
Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.
|
2 | P21524 (/IMP) P21524 (/IMP) |
Ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor GO:0004748
Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.
|
2 | Q5A0N3 (/NAS) Q5A0N3 (/NAS) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
2 | P36602 (/ISM) P36602 (/ISM) |
CDP reductase activity GO:0051063
Catalysis of the reaction: dCDP + thioredoxin disulfide + H2O = CDP + thioredoxin.
|
2 | P36602 (/IDA) P36602 (/IDA) |
Purine nucleotide binding GO:0017076
Interacting selectively and non-covalently with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate.
|
1 | P07742 (/IDA) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | P07742 (/ISO) |
Disordered domain specific binding GO:0097718
Interacting selectively and non-covalently with a disordered domain of a protein.
|
1 | P07742 (/IPI) |
There are 24 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Deoxyribonucleotide biosynthetic process GO:0009263
The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
|
12 |
P21524 (/ISS)
P21524 (/ISS)
P23921 (/ISS)
P36602 (/ISS)
P36602 (/ISS)
P48591 (/ISS)
P79732 (/ISS)
Q03604 (/ISS)
Q5R919 (/ISS)
Q9SJ20 (/ISS)
(2 more) |
Deoxyribonucleotide biosynthetic process GO:0009263
The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
|
5 | P07742 (/IDA) P21524 (/IDA) P21524 (/IDA) P21672 (/IDA) P21672 (/IDA) |
DTTP biosynthetic process GO:0006235
The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate.
|
2 | P36602 (/IMP) P36602 (/IMP) |
DCDP biosynthetic process GO:0006240
The chemical reactions and pathways resulting in the formation of dCDP, deoxycytidine 5'-diphosphate.
|
2 | P36602 (/IDA) P36602 (/IDA) |
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
|
2 | Q5A0N3 (/IMP) Q5A0N3 (/IMP) |
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
|
2 | Q5A0N3 (/IMP) Q5A0N3 (/IMP) |
Filamentous growth of a population of unicellular organisms in response to starvation GO:0036170
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
|
2 | Q5A0N3 (/IMP) Q5A0N3 (/IMP) |
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
|
2 | Q5A0N3 (/IMP) Q5A0N3 (/IMP) |
CDP metabolic process GO:0046704
The chemical reactions and pathways involving CDP, cytidine (5'-)diphosphate.
|
2 | P36602 (/IDA) P36602 (/IDA) |
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
|
1 | Q5U2Q5 (/IEP) |
Pyrimidine nucleobase metabolic process GO:0006206
The chemical reactions and pathways involving pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.
|
1 | Q5U2Q5 (/IEP) |
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
|
1 | Q9SJ20 (/IMP) |
Activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919
Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process.
|
1 | P48591 (/IMP) |
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
|
1 | Q5U2Q5 (/IEP) |
Deoxyribonucleoside triphosphate biosynthetic process GO:0009202
The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.
|
1 | Q9SJ20 (/IMP) |
Response to ionizing radiation GO:0010212
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
|
1 | Q5U2Q5 (/IEP) |
Nucleobase-containing small molecule interconversion GO:0015949
The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.
|
1 | P23921 (/TAS) |
Cell proliferation in forebrain GO:0021846
The creation of greater cell numbers in the forebrain due to cell division of progenitor cells.
|
1 | Q5U2Q5 (/IEP) |
Tissue regeneration GO:0042246
The regrowth of lost or destroyed tissues.
|
1 | P48591 (/IMP) |
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
|
1 | Q9SJ20 (/IEP) |
Protein complex oligomerization GO:0051259
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
1 | P07742 (/IPI) |
Protein heterotetramerization GO:0051290
The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
|
1 | P07742 (/IDA) |
Protein heterotetramerization GO:0051290
The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
|
1 | P07742 (/IPI) |
Retina development in camera-type eye GO:0060041
The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
|
1 | Q5U2Q5 (/IEP) |
There are 19 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | P21524 (/IDA) P21524 (/IDA) P21672 (/IDA) P21672 (/IDA) Q5U2Q5 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | P21524 (/HDA) P21524 (/HDA) P36602 (/HDA) P36602 (/HDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | P21524 (/HDA) P21524 (/HDA) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | P21672 (/HDA) P21672 (/HDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | P36602 (/HDA) P36602 (/HDA) |
Ribonucleoside-diphosphate reductase complex GO:0005971
An enzyme complex composed of 2-4 or more subunits, which usually contains nonheme iron and requires ATP for catalysis. Catalyzes the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor.
|
2 | P21524 (/IDA) P21524 (/IDA) |
Ribonucleoside-diphosphate reductase complex GO:0005971
An enzyme complex composed of 2-4 or more subunits, which usually contains nonheme iron and requires ATP for catalysis. Catalyzes the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor.
|
2 | P36602 (/IPI) P36602 (/IPI) |
Ribonucleoside-diphosphate reductase complex GO:0005971
An enzyme complex composed of 2-4 or more subunits, which usually contains nonheme iron and requires ATP for catalysis. Catalyzes the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor.
|
2 | P21672 (/TAS) P21672 (/TAS) |
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
|
1 | Q5U2Q5 (/IDA) |
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
|
1 | P07742 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P07742 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P23921 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P07742 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P23921 (/TAS) |
Ribonucleoside-diphosphate reductase complex GO:0005971
An enzyme complex composed of 2-4 or more subunits, which usually contains nonheme iron and requires ATP for catalysis. Catalyzes the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor.
|
1 | P07742 (/IMP) |
Cell projection GO:0042995
A prolongation or process extending from a cell, e.g. a flagellum or axon.
|
1 | Q5U2Q5 (/IDA) |
Cell projection GO:0042995
A prolongation or process extending from a cell, e.g. a flagellum or axon.
|
1 | P07742 (/ISO) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
1 | Q5U2Q5 (/IDA) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
1 | P07742 (/ISO) |