The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Glycosidases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 16: Maltase-glucoamylase, intestinal

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Alpha-1,4-glucosidase activity GO:0004558
Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.
13 A0A0J9YVE6 (/IDA) A0A0J9YVJ0 (/IDA) B5THE2 (/IDA) B5THE2 (/IDA) P56526 (/IDA) P56526 (/IDA) P56526 (/IDA) P56526 (/IDA) P56526 (/IDA) P56526 (/IDA)
(3 more)
Beta-fructofuranosidase activity GO:0004564
Catalysis of the reaction: a fructofuranosylated fructofuranosyl acceptor + H2O = a non fructofuranosylated fructofuranosyl acceptor + a beta-D-fructofuranoside.
4 B5THE3 (/ISO) B5THE3 (/ISO) F8VQM5 (/ISO) F8VQM5 (/ISO)
Oligo-1,6-glucosidase activity GO:0004574
Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose. Releases a free alpha-D-glucose.
4 B5THE3 (/ISO) B5THE3 (/ISO) F8VQM5 (/ISO) F8VQM5 (/ISO)
Amylase activity GO:0016160
Catalysis of the hydrolysis of amylose or an amylose derivative.
4 A0A0J9YVE6 (/IDA) A0A0J9YVJ0 (/IDA) B5THE2 (/IDA) B5THE2 (/IDA)
Catalytic activity GO:0003824
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
2 O43451 (/TAS) O43451 (/TAS)
Beta-fructofuranosidase activity GO:0004564
Catalysis of the reaction: a fructofuranosylated fructofuranosyl acceptor + H2O = a non fructofuranosylated fructofuranosyl acceptor + a beta-D-fructofuranoside.
2 P23739 (/IDA) P23739 (/IDA)
Oligo-1,6-glucosidase activity GO:0004574
Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose. Releases a free alpha-D-glucose.
2 P23739 (/IDA) P23739 (/IDA)
Sucrose alpha-glucosidase activity GO:0004575
Catalysis of the reaction: sucrose + H2O = alpha-D-glucose + beta-D-fructose.
2 P14410 (/TAS) P14410 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P23739 (/IPI) P23739 (/IPI)
Alpha-1,4-glucosidase activity GO:0004558
Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.
1 O04931 (/IMP)
Alpha-1,4-glucosidase activity GO:0004558
Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.
1 Q1HFV4 (/RCA)
Xylan 1,4-beta-xylosidase activity GO:0009044
Catalysis of the hydrolysis of (1->4)-beta-D-xylans so as to remove successive D-xylose residues from the non-reducing termini.
1 Q9S7Y7 (/IDA)
Alpha-L-arabinofuranosidase activity GO:0046556
Catalysis of the hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.
1 Q9S7Y7 (/IDA)
Xyloglucan 1,6-alpha-xylosidase activity GO:0080176
Catalysis of the hydrolysis of xyloglucan side chains so as to remove unsubstituted D-xylose residues attached to the glucose located at the non-reducing terminus.
1 Q9S7Y7 (/IDA)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Polysaccharide digestion GO:0044245
The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested polysaccharides into components that may be easily absorbed and directed into metabolism.
4 O43451 (/TAS) O43451 (/TAS) P14410 (/TAS) P14410 (/TAS)
Cellular carbohydrate catabolic process GO:0044275
The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
3 Q1HFV4 (/IDA) Q5BET9 (/IDA) Q5BET9 (/IDA)
Starch catabolic process GO:0005983
The chemical reactions and pathways resulting in the breakdown of starch, the most important reserve polysaccharide in plants.
2 O43451 (/TAS) O43451 (/TAS)
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
2 P23739 (/IEP) P23739 (/IEP)
Response to nutrient GO:0007584
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
2 P23739 (/IEP) P23739 (/IEP)
Response to sucrose GO:0009744
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
2 P23739 (/IEP) P23739 (/IEP)
Response to fructose GO:0009750
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.
2 P23739 (/IEP) P23739 (/IEP)
Response to insulin GO:0032868
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
2 P23739 (/IEP) P23739 (/IEP)
Response to vitamin A GO:0033189
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.
2 P23739 (/IEP) P23739 (/IEP)
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
2 P23739 (/IEP) P23739 (/IEP)
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
2 O43451 (/TAS) O43451 (/TAS)
Response to glucocorticoid GO:0051384
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
2 P23739 (/IEP) P23739 (/IEP)
Maltose metabolic process GO:0000023
The chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch.
1 Q1HFV4 (/RCA)
Starch metabolic process GO:0005982
The chemical reactions and pathways involving starch, the most important reserve polysaccharide in plants. It is a glucan consisting of two components, amylose and amylopectin, which are both glucose homopolymers. Starch is synthesized as a temporary storage form of carbon and can be catabolized to produce sucrose.
1 Q1HFV4 (/IEP)
Xyloglucan metabolic process GO:0010411
The chemical reactions and pathways involving xyloglucan, the cross-linking glycan composed of (1->4)-beta-D-glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants.
1 Q9S7Y7 (/IMP)
Xylan catabolic process GO:0045493
The chemical reactions and pathways resulting in the breakdown of xylan, a polymer containing a beta-1,4-linked D-xylose backbone.
1 Q9S7Y7 (/IDA)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
1 Q9S7Y7 (/IEP)

There are 17 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Brush border GO:0005903
The dense covering of microvilli on the apical surface of a epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.
6 B5THE3 (/TAS) B5THE3 (/TAS) F8VQM5 (/TAS) F8VQM5 (/TAS) P14410 (/TAS) P14410 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 O43451 (/TAS) O43451 (/TAS) P14410 (/TAS) P14410 (/TAS)
Brush border GO:0005903
The dense covering of microvilli on the apical surface of a epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.
4 B5THE3 (/IDA) B5THE3 (/IDA) P23739 (/IDA) P23739 (/IDA)
Brush border GO:0005903
The dense covering of microvilli on the apical surface of a epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.
4 B5THE3 (/ISO) B5THE3 (/ISO) F8VQM5 (/ISO) F8VQM5 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
4 B5THE3 (/IDA) B5THE3 (/IDA) F8VQM5 (/IDA) F8VQM5 (/IDA)
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
4 B5THE3 (/ISO) B5THE3 (/ISO) F8VQM5 (/ISO) F8VQM5 (/ISO)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
4 O43451 (/HDA) O43451 (/HDA) P14410 (/HDA) P14410 (/HDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
2 P14410 (/TAS) P14410 (/TAS)
Plant-type cell wall GO:0009505
A more or less rigid stucture lying outside the cell membrane of a cell and composed of cellulose and pectin and other organic and inorganic substances.
2 Q9LYF8 (/IDA) Q9S7Y7 (/IDA)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
2 F4J6T7 (/IDA) Q9S7Y7 (/IDA)
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
2 P23739 (/IDA) P23739 (/IDA)
Apoplast GO:0048046
The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
2 Q9LYF8 (/IDA) Q9S7Y7 (/IDA)
Tertiary granule membrane GO:0070821
The lipid bilayer surrounding a tertiary granule.
2 O43451 (/TAS) O43451 (/TAS)
Ficolin-1-rich granule membrane GO:0101003
The lipid bilayer surrounding a ficolin-1-rich granule.
2 O43451 (/TAS) O43451 (/TAS)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
1 Q9S7Y7 (/IDA)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
1 Q9LYF8 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
1 Q9S7Y7 (/IDA)
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