The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 91: galactocerebrosidase precursor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Galactosylceramidase activity GO:0004336
Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine.
12 B5X3C1 (/ISS) B5X3C1 (/ISS) O02791 (/ISS) O02791 (/ISS) O02791 (/ISS) P54803 (/ISS) P54803 (/ISS) P54804 (/ISS) Q0VA39 (/ISS) Q498K0 (/ISS)
(2 more)
Galactosylceramidase activity GO:0004336
Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine.
4 F1QYH2 (/IDA) P54818 (/IDA) Q5SNX7 (/IDA) Q7ZUD5 (/IDA)
Galactosylceramidase activity GO:0004336
Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine.
2 P54803 (/TAS) P54803 (/TAS)
Galactosylceramidase activity GO:0004336
Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine.
1 P54818 (/IMP)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Galactosylceramide catabolic process GO:0006683
The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
12 B5X3C1 (/ISS) B5X3C1 (/ISS) O02791 (/ISS) O02791 (/ISS) O02791 (/ISS) P54803 (/ISS) P54803 (/ISS) P54804 (/ISS) Q0VA39 (/ISS) Q498K0 (/ISS)
(2 more)
Glycosphingolipid metabolic process GO:0006687
The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide.
2 P54803 (/TAS) P54803 (/TAS)
Galactosylceramide catabolic process GO:0006683
The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
1 P54818 (/IDA)
Galactosylceramide catabolic process GO:0006683
The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
1 P54818 (/IMP)
Myelination GO:0042552
The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
1 P54818 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
3 F1QYH2 (/IDA) Q5SNX7 (/IDA) Q7ZUD5 (/IDA)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
3 P54803 (/TAS) P54803 (/TAS) P54818 (/TAS)
Lysosomal lumen GO:0043202
The volume enclosed within the lysosomal membrane.
2 P54803 (/TAS) P54803 (/TAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 P54818 (/HDA)
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