The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Aldolase class I
".
FunFam 71: Hydroxymethylglutaryl-CoA lyase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Hydroxymethylglutaryl-CoA lyase activity GO:0004419
Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.
|
37 |
O34873 (/ISS)
O34873 (/ISS)
O34873 (/ISS)
O34873 (/ISS)
Q48IG1 (/ISS)
Q48IG1 (/ISS)
Q48IG1 (/ISS)
Q48IG1 (/ISS)
Q48IG1 (/ISS)
Q5LPR1 (/ISS)
(27 more) |
Hydroxymethylglutaryl-CoA lyase activity GO:0004419
Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.
|
8 | Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) |
Metal ion binding GO:0046872
Interacting selectively and non-covalently with any metal ion.
|
4 | O34873 (/ISS) O34873 (/ISS) O34873 (/ISS) O34873 (/ISS) |
Oxo-acid-lyase activity GO:0016833
Catalysis of the cleavage of a C-C bond by other means than by hydrolysis or oxidation, of a 3-hydroxy acid.
|
1 | A9WGE2 (/IDA) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Generation of precursor metabolites and energy GO:0006091
The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.
|
19 |
Q81Q83 (/ISS)
Q81Q83 (/ISS)
Q81Q83 (/ISS)
Q81Q83 (/ISS)
Q81Q83 (/ISS)
Q81Q83 (/ISS)
Q81Q83 (/ISS)
Q81Q83 (/ISS)
Q81Q83 (/ISS)
Q81Q83 (/ISS)
(9 more) |
Leucine catabolic process GO:0006552
The chemical reactions and pathways resulting in the breakdown of leucine, 2-amino-4-methylpentanoic acid.
|
8 | Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) |
Isoprenoid catabolic process GO:0008300
The chemical reactions and pathways resulting in the breakdown of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
|
8 | Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) |
Terpene catabolic process GO:0046247
The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units.
|
8 | Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) Q9I2A0 (/IMP) |
Glyoxylate catabolic process GO:0009436
The chemical reactions and pathways resulting in the breakdown of glyoxylate, the anion of glyoxylic acid, HOC-COOH.
|
1 | A9WGE2 (/IDA) |
Farnesyl diphosphate biosynthetic process, mevalonate pathway GO:0010142
The pathway that converts acetate, in the form of acetyl-CoA, to farnesyl diphosphate (FPP) through a series of mevalonate intermediates. Farnesyl diphosphate is an important substrate for other essential pathways, such as biosynthesis of sterols.
|
1 | Q5LPR1 (/ISS) |
Carbon fixation by 3-hydroxypropionate cycle GO:0043427
An autotrophic carbon dioxide fixation pathway by which two molecules of carbon dioxide are fixed to form glyoxylate. Acetyl coenzyme A (acetyl-CoA) is assumed to be converted to malate, and two CO2 molecules are thereby fixed. Malyl-CoA is thought to be cleaved to acetyl-CoA, the starting molecule, and glyoxylate, the carbon fixation product.
|
1 | A9WGE2 (/IDA) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.