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CATH Superfamily 3.20.20.70

Aldolase class I

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: Imidazole glycerol phosphate synthase subunit HisF

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Imidazoleglycerol-phosphate synthase activity GO:0000107
Catalysis of the reaction: phosphoribulosylformimino-AICAR-P + L-glutamine = D-erythro-imidazole-glycerol-phosphate + aminoimidazole carboxamide ribonucleotide + L-glutamate + 2 H(+).
 47 P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA)
(37 more)
Imidazoleglycerol-phosphate synthase activity GO:0000107
Catalysis of the reaction: phosphoribulosylformimino-AICAR-P + L-glutamine = D-erythro-imidazole-glycerol-phosphate + aminoimidazole carboxamide ribonucleotide + L-glutamate + 2 H(+).
 11 Q9KSW8 (/ISS) Q9KSW8 (/ISS) Q9KSW8 (/ISS) Q9KSW8 (/ISS) Q9KSW8 (/ISS) Q9KSW8 (/ISS) Q9KSW8 (/ISS) Q9KSW8 (/ISS) Q9KSW8 (/ISS) Q9KSW8 (/ISS)
(1 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 2 Q9X0C6 (/IPI) Q9X0C6 (/IPI)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Histidine biosynthetic process GO:0000105
The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
 47 P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA)
(37 more)
Histidine biosynthetic process GO:0000105
The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
 11 Q9KSW8 (/ISS) Q9KSW8 (/ISS) Q9KSW8 (/ISS) Q9KSW8 (/ISS) Q9KSW8 (/ISS) Q9KSW8 (/ISS) Q9KSW8 (/ISS) Q9KSW8 (/ISS) Q9KSW8 (/ISS) Q9KSW8 (/ISS)
(1 more)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 47 P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA)
(37 more)
Imidazoleglycerol-phosphate synthase complex GO:0009382
Complex that possesses imidazoleglycerol-phosphate synthase activity.
 47 P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA) P60664 (/IDA)
(37 more)