The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: GMP reductase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
IMP dehydrogenase activity GO:0003938
Catalysis of the reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+.
121 P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA)
(111 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
113 P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA)
(103 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
13 Q9HXM5 (/IPI) Q9HXM5 (/IPI) Q9HXM5 (/IPI) Q9HXM5 (/IPI) Q9HXM5 (/IPI) Q9HXM5 (/IPI) Q9HXM5 (/IPI) Q9HXM5 (/IPI) Q9HXM5 (/IPI) Q9HXM5 (/IPI)
(3 more)
IMP dehydrogenase activity GO:0003938
Catalysis of the reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+.
5 Q9KTW3 (/ISS) Q9KTW3 (/ISS) Q9KTW3 (/ISS) Q9KTW3 (/ISS) Q9KTW3 (/ISS)
GMP reductase activity GO:0003920
Catalysis of the reaction: IMP + NADP(+) + NH(4)(+) = GMP + 2 H(+) + NADPH.
2 Q57ZS7 (/IDA) Q57ZS7 (/IDA)
GMP reductase activity GO:0003920
Catalysis of the reaction: IMP + NADP(+) + NH(4)(+) = GMP + 2 H(+) + NADPH.
1 Q4QEB3 (/ISO)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to UV GO:0009411
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
113 P0ADG7 (/IMP) P0ADG7 (/IMP) P0ADG7 (/IMP) P0ADG7 (/IMP) P0ADG7 (/IMP) P0ADG7 (/IMP) P0ADG7 (/IMP) P0ADG7 (/IMP) P0ADG7 (/IMP) P0ADG7 (/IMP)
(103 more)
GMP biosynthetic process GO:0006177
The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate.
8 P9WKI7 (/IDA) P9WKI7 (/IDA) P9WKI7 (/IDA) P9WKI7 (/IDA) P9WKI7 (/IDA) P9WKI7 (/IDA) P9WKI7 (/IDA) P9WKI7 (/IDA)
IMP catabolic process GO:0006204
The chemical reactions and pathways resulting in the breakdown of IMP, inosine monophosphate.
8 P9WKI7 (/IDA) P9WKI7 (/IDA) P9WKI7 (/IDA) P9WKI7 (/IDA) P9WKI7 (/IDA) P9WKI7 (/IDA) P9WKI7 (/IDA) P9WKI7 (/IDA)
XMP biosynthetic process GO:0097293
The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate.
8 P9WKI7 (/IDA) P9WKI7 (/IDA) P9WKI7 (/IDA) P9WKI7 (/IDA) P9WKI7 (/IDA) P9WKI7 (/IDA) P9WKI7 (/IDA) P9WKI7 (/IDA)
Purine ribonucleotide biosynthetic process GO:0009152
The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
5 Q9KTW3 (/ISS) Q9KTW3 (/ISS) Q9KTW3 (/ISS) Q9KTW3 (/ISS) Q9KTW3 (/ISS)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
113 P0ADG7 (/HDA) P0ADG7 (/HDA) P0ADG7 (/HDA) P0ADG7 (/HDA) P0ADG7 (/HDA) P0ADG7 (/HDA) P0ADG7 (/HDA) P0ADG7 (/HDA) P0ADG7 (/HDA) P0ADG7 (/HDA)
(103 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
113 P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA) P0ADG7 (/IDA)
(103 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
8 P9WKI7 (/HDA) P9WKI7 (/HDA) P9WKI7 (/HDA) P9WKI7 (/HDA) P9WKI7 (/HDA) P9WKI7 (/HDA) P9WKI7 (/HDA) P9WKI7 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
8 P9WKI7 (/HDA) P9WKI7 (/HDA) P9WKI7 (/HDA) P9WKI7 (/HDA) P9WKI7 (/HDA) P9WKI7 (/HDA) P9WKI7 (/HDA) P9WKI7 (/HDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
2 Q57ZS7 (/IDA) Q57ZS7 (/IDA)
Glycosome GO:0020015
A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.
2 Q57ZS7 (/IDA) Q57ZS7 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 Q4QEB3 (/ISO)
Glycosome GO:0020015
A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.
1 Q4QEB3 (/ISO)
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