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CATH Superfamily 3.20.20.70

Aldolase class I

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 28: Dihydroorotate dehydrogenase (quinone)

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Dihydroorotate dehydrogenase activity GO:0004152
Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate.
 91 P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA)
(81 more)
FMN binding GO:0010181
Interacting selectively and non-covalently with flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
 91 P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA)
(81 more)
Dihydroorotate oxidase activity GO:0004158
Catalysis of the reaction: (S)-dihydroorotate + O(2) = H(2)O(2) + orotate.
 7 Q9KRZ2 (/ISS) Q9KRZ2 (/ISS) Q9KRZ2 (/ISS) Q9KRZ2 (/ISS) Q9KRZ2 (/ISS) Q9KRZ2 (/ISS) Q9KRZ2 (/ISS)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
'de novo' pyrimidine nucleobase biosynthetic process GO:0006207
The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors.
 91 P0A7E1 (/IMP) P0A7E1 (/IMP) P0A7E1 (/IMP) P0A7E1 (/IMP) P0A7E1 (/IMP) P0A7E1 (/IMP) P0A7E1 (/IMP) P0A7E1 (/IMP) P0A7E1 (/IMP) P0A7E1 (/IMP)
(81 more)
Pyrimidine ribonucleotide biosynthetic process GO:0009220
The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
 7 Q9KRZ2 (/ISS) Q9KRZ2 (/ISS) Q9KRZ2 (/ISS) Q9KRZ2 (/ISS) Q9KRZ2 (/ISS) Q9KRZ2 (/ISS) Q9KRZ2 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 91 P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA)
(81 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 91 P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA) P0A7E1 (/IDA)
(81 more)