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CATH Superfamily 3.20.20.70

Aldolase class I

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 269: Putative 2-dehydro-3-deoxy-D-gluconate aldolase Ya...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
2-dehydro-3-deoxy-D-pentonate aldolase. [EC: 4.1.2.28]
2-dehydro-3-deoxy-D-pentonate = pyruvate + glycolaldehyde.
    		 40 A0A066T2Z3 A0A066T2Z3 A0A066T2Z3 A0A066T2Z3 A0A066T2Z3 A0A066T2Z3 A0A376PKQ1 A0A376PKQ1 A0A3S0WAE7 A0A3S0WAE7
    (30 more...)
    2-dehydro-3-deoxy-D-gluconate aldolase. [EC: 4.1.2.51]
    2-dehydro-3-deoxy-D-gluconate = pyruvate + D-glyceraldehyde.
    • The enzyme from the archaeon Picrophilus torridus is involved in D-glucose and D-galactose catabolism via the nonphosphorylative variant of the Entner-Doudoroff pathway.
    • In the direction of aldol synthesis the enzyme catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate and 2-dehydro-3-deoxy-D- galactonate at a similar ratio.
    • It shows no activity with 2-dehydro-3-deoxy-D-gluconate 6-phosphate.
    • Cf. EC 4.1.2.14.
    		 4 A0A376PKQ1 A0A376PKQ1 P75682 P75682
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