The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Transaldolase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity GO:0004801
Catalysis of the reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.
1271 A0K9A9 (/ISS) A0K9A9 (/ISS) A0L002 (/ISS) A1JJD0 (/ISS) A1JJD0 (/ISS) A1JJD0 (/ISS) A1JJD0 (/ISS) A1JJD0 (/ISS) A1RMN6 (/ISS) A1RMN6 (/ISS)
(1261 more)
Sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity GO:0004801
Catalysis of the reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.
99 K0BE10 (/IDA) K0BE10 (/IDA) K0BE10 (/IDA) K0BE10 (/IDA) K0BE10 (/IDA) K0BE10 (/IDA) K0BE10 (/IDA) K0BE10 (/IDA) K0BE10 (/IDA) K0BE10 (/IDA)
(89 more)
Transferase activity, transferring aldehyde or ketonic groups GO:0016744
Catalysis of the transfer of an aldehyde or ketonic group from one compound (donor) to another (acceptor).
57 P0A870 (/IDA) P0A870 (/IDA) P0A870 (/IDA) P0A870 (/IDA) P0A870 (/IDA) P0A870 (/IDA) P0A870 (/IDA) P0A870 (/IDA) P0A870 (/IDA) P0A870 (/IDA)
(47 more)
Sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity GO:0004801
Catalysis of the reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.
2 P37837 (/TAS) P37837 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P37837 (/IPI) P37837 (/IPI)
Sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity GO:0004801
Catalysis of the reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.
1 Q93092 (/ISO)
Carbohydrate binding GO:0030246
Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
1 Q9EQS0 (/IDA)
Carbohydrate binding GO:0030246
Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
1 Q93092 (/ISO)
Monosaccharide binding GO:0048029
Interacting selectively and non-covalently with any monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H
1 Q9EQS0 (/IDA)
Monosaccharide binding GO:0048029
Interacting selectively and non-covalently with any monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H
1 Q93092 (/ISO)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pentose-phosphate shunt, non-oxidative branch GO:0009052
The branch of the pentose-phosphate shunt which does not involve oxidation reactions. It comprises a series of sugar phosphate interconversions, starting with ribulose 5-P and producing fructose 6-P and glyceraldehyde 3-P.
58 P0A870 (/IDA) P0A870 (/IDA) P0A870 (/IDA) P0A870 (/IDA) P0A870 (/IDA) P0A870 (/IDA) P0A870 (/IDA) P0A870 (/IDA) P0A870 (/IDA) P0A870 (/IDA)
(48 more)
Pentose-phosphate shunt GO:0006098
The glucose-6-phosphate catabolic process in which, coupled to NADPH synthesis, glucose-6-P is oxidized with the formation of carbon dioxide (CO2) and ribulose 5-phosphate; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses.
10 Q9KLW8 (/ISS) Q9KLW8 (/ISS) Q9KLW8 (/ISS) Q9KLW8 (/ISS) Q9KLW8 (/ISS) Q9KLW8 (/ISS) Q9KLW8 (/ISS) Q9KLW8 (/ISS) Q9KLW8 (/ISS) Q9KLW8 (/ISS)
Carbohydrate metabolic process GO:0005975
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
2 P37837 (/TAS) P37837 (/TAS)
Xylulose biosynthetic process GO:0005999
The chemical reactions and pathways resulting in the formation of xylulose, the ketopentose threo-2-pentulose.
2 P37837 (/TAS) P37837 (/TAS)
Pentose-phosphate shunt GO:0006098
The glucose-6-phosphate catabolic process in which, coupled to NADPH synthesis, glucose-6-P is oxidized with the formation of carbon dioxide (CO2) and ribulose 5-phosphate; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses.
2 P37837 (/TAS) P37837 (/TAS)
Interleukin-12-mediated signaling pathway GO:0035722
A series of molecular signals initiated by the binding of interleukin-12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2 P37837 (/TAS) P37837 (/TAS)
Fructose 6-phosphate metabolic process GO:0006002
The chemical reactions and pathways involving fructose 6-phosphate, also known as F6P. The D-enantiomer is an important intermediate in glycolysis, gluconeogenesis, and fructose metabolism.
1 Q9EQS0 (/IDA)
Fructose 6-phosphate metabolic process GO:0006002
The chemical reactions and pathways involving fructose 6-phosphate, also known as F6P. The D-enantiomer is an important intermediate in glycolysis, gluconeogenesis, and fructose metabolism.
1 Q93092 (/ISO)
Pentose-phosphate shunt GO:0006098
The glucose-6-phosphate catabolic process in which, coupled to NADPH synthesis, glucose-6-P is oxidized with the formation of carbon dioxide (CO2) and ribulose 5-phosphate; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses.
1 Q9EQS0 (/IDA)
Pentose-phosphate shunt GO:0006098
The glucose-6-phosphate catabolic process in which, coupled to NADPH synthesis, glucose-6-P is oxidized with the formation of carbon dioxide (CO2) and ribulose 5-phosphate; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses.
1 Q93092 (/ISO)
Pentose-phosphate shunt, non-oxidative branch GO:0009052
The branch of the pentose-phosphate shunt which does not involve oxidation reactions. It comprises a series of sugar phosphate interconversions, starting with ribulose 5-P and producing fructose 6-P and glyceraldehyde 3-P.
1 Q93092 (/ISO)
Glyceraldehyde-3-phosphate metabolic process GO:0019682
The chemical reactions and pathways involving glyceraldehyde-3-phosphate, an important intermediate in glycolysis.
1 Q9EQS0 (/IDA)
Glyceraldehyde-3-phosphate metabolic process GO:0019682
The chemical reactions and pathways involving glyceraldehyde-3-phosphate, an important intermediate in glycolysis.
1 Q93092 (/ISO)

There are 14 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
173 A0A140VK56 (/IDA) A0A140VK56 (/IDA) F2Z393 (/IDA) P0A867 (/IDA) P0A867 (/IDA) P0A867 (/IDA) P0A867 (/IDA) P0A867 (/IDA) P0A867 (/IDA) P0A867 (/IDA)
(163 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
57 P0A870 (/HDA) P0A870 (/HDA) P0A870 (/HDA) P0A870 (/HDA) P0A870 (/HDA) P0A870 (/HDA) P0A870 (/HDA) P0A870 (/HDA) P0A870 (/HDA) P0A870 (/HDA)
(47 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
57 P0A870 (/HDA) P0A870 (/HDA) P0A870 (/HDA) P0A870 (/HDA) P0A870 (/HDA) P0A870 (/HDA) P0A870 (/HDA) P0A870 (/HDA) P0A870 (/HDA) P0A870 (/HDA)
(47 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 A0A140VK56 (/IDA) A0A140VK56 (/IDA) F2Z393 (/IDA) P37837 (/IDA) P37837 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
5 A0A140VK56 (/IDA) A0A140VK56 (/IDA) F2Z393 (/IDA) P37837 (/IDA) P37837 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P37837 (/HDA) P37837 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P37837 (/TAS) P37837 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P37837 (/TAS) P37837 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 P37837 (/HDA) P37837 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q93092 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q93092 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q93092 (/ISO)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 Q9EQS0 (/IDA)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 Q93092 (/ISO)