The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 187: Fructose-bisphosphate aldolase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
17 Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA)
(7 more)
Fructose-bisphosphate aldolase activity GO:0004332
Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde-3-phosphate.
17 Q7KQL9 (/TAS) Q7KQL9 (/TAS) Q7KQL9 (/TAS) Q7KQL9 (/TAS) Q7KQL9 (/TAS) Q7KQL9 (/TAS) Q7KQL9 (/TAS) Q7KQL9 (/TAS) Q7KQL9 (/TAS) Q7KQL9 (/TAS)
(7 more)
Fructose-bisphosphate aldolase activity GO:0004332
Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde-3-phosphate.
5 B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 B9PW35 (/IPI) B9PW35 (/IPI) B9PW35 (/IPI) B9PW35 (/IPI) B9PW35 (/IPI)
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
5 B9PW35 (/IPI) B9PW35 (/IPI) B9PW35 (/IPI) B9PW35 (/IPI) B9PW35 (/IPI)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
17 Q7KQL9 (/TAS) Q7KQL9 (/TAS) Q7KQL9 (/TAS) Q7KQL9 (/TAS) Q7KQL9 (/TAS) Q7KQL9 (/TAS) Q7KQL9 (/TAS) Q7KQL9 (/TAS) Q7KQL9 (/TAS) Q7KQL9 (/TAS)
(7 more)
Actin polymerization or depolymerization GO:0008154
Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.
17 Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA)
(7 more)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
5 B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP)
Entry into host cell GO:0030260
The invasion by an organism of a cell of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
5 B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP)
Fructose 1,6-bisphosphate metabolic process GO:0030388
The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.
5 B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP)
Symbiont process GO:0044403
A process carried out by symbiont gene products that enables the interaction between two organisms living together in more or less intimate association. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts.
5 B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP)
Adhesion of symbiont to host cell GO:0044650
The attachment of a symbiont to a host cell via adhesion molecules, general stickiness etc., either directly or indirectly.
5 B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP)
Positive regulation of ATP biosynthetic process GO:2001171
Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process.
5 B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
17 Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA) Q7KQL9 (/IDA)
(7 more)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
5 B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP)
Apical cytoplasm GO:0090651
The region of the cytoplasm located at the apical side of the cell. Used in reference to animal polarized epithelial cells.
5 B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP) B9PW35 (/IMP)
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