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CATH Superfamily 3.20.20.70

Aldolase class I

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: GMP reductase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GMP reductase activity GO:0003920
Catalysis of the reaction: IMP + NADP(+) + NH(4)(+) = GMP + 2 H(+) + NADPH.
 101 P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA)
(91 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 101 P60560 (/IPI) P60560 (/IPI) P60560 (/IPI) P60560 (/IPI) P60560 (/IPI) P60560 (/IPI) P60560 (/IPI) P60560 (/IPI) P60560 (/IPI) P60560 (/IPI)
(91 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 100 P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA)
(90 more)
GMP reductase activity GO:0003920
Catalysis of the reaction: IMP + NADP(+) + NH(4)(+) = GMP + 2 H(+) + NADPH.
 10 Q32L93 (/ISS) Q99L27 (/ISS) Q9KMW9 (/ISS) Q9KMW9 (/ISS) Q9KMW9 (/ISS) Q9KMW9 (/ISS) Q9KMW9 (/ISS) Q9KMW9 (/ISS) Q9KMW9 (/ISS) Q9KMW9 (/ISS)
GMP reductase activity GO:0003920
Catalysis of the reaction: IMP + NADP(+) + NH(4)(+) = GMP + 2 H(+) + NADPH.
 1 Q99L27 (/ISO)
GMP reductase activity GO:0003920
Catalysis of the reaction: IMP + NADP(+) + NH(4)(+) = GMP + 2 H(+) + NADPH.
 1 P36959 (/TAS)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Purine ribonucleotide interconversion GO:0015951
The chemical reactions and pathways by which a purine ribonucleotide is synthesized from another purine ribonucleotide.
 100 P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA)
(90 more)
Nucleobase-containing small molecule interconversion GO:0015949
The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.
 8 Q9KMW9 (/ISS) Q9KMW9 (/ISS) Q9KMW9 (/ISS) Q9KMW9 (/ISS) Q9KMW9 (/ISS) Q9KMW9 (/ISS) Q9KMW9 (/ISS) Q9KMW9 (/ISS)
Purine-containing compound salvage GO:0043101
Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis.
 2 P36959 (/TAS) Q9P2T1 (/TAS)
GMP metabolic process GO:0046037
The chemical reactions and pathways involving GMP, guanosine monophosphate.
 2 Q32L93 (/ISS) Q99L27 (/ISS)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
 1 Q9Z244 (/IEP)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
 1 P36959 (/TAS)
Monocyte differentiation GO:0030224
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte.
 1 Q99L27 (/ISO)
GMP metabolic process GO:0046037
The chemical reactions and pathways involving GMP, guanosine monophosphate.
 1 Q9P2T1 (/IDA)
GMP catabolic process GO:0046038
The chemical reactions and pathways resulting in the breakdown of GMP, guanosine monophosphate.
 1 Q99L27 (/ISO)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 100 P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA) P60560 (/IDA)
(90 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 2 P36959 (/TAS) Q9P2T1 (/TAS)